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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 8, 2024 | 6:39 AM IST

Grisoclix 500mg Tablet is used to treat fungal infections of the skin like ringworm, jock itch, athlete's foot, and fungal infections of nails and hair. It contains Griseofulvin, which works by binding to the keratin (a protein that is formed in the cells of the skin, hair follicles, and nail bed) and inhibits the growth and multiplication of fungal cells. Thereby, it prevents newly grown keratin from being infected by fungal cells. The infected keratin dies and sheds from the body, leaving new healthy keratin. Some people may experience side effects such as nausea, diarrhoea, headache, and discomfort in the stomach. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type

ORAL

Return Policy

Not Returnable

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About Grisoclix 500mg Tablet

Grisoclix 500mg Tablet is used to treat fungal infections of the skin like ringworm, jock itch, athlete’s foot, and fungal infections of nails and hair. Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Grisoclix 500mg Tablet contains Griseofulvin, which works by binding to the keratin (a protein that is formed in the cells of the skin, hair follicles, and nail bed) and inhibits the growth and multiplication of fungal cells. Thereby, it prevents newly grown keratin from being infected by fungal cells. The infected keratin dies and sheds from the body, leaving new healthy keratin.

Take Grisoclix 500mg Tablet as prescribed. Your doctor will advise you on how often you need to take Grisoclix 500mg Tablet based on your medical condition. Some people may experience nausea, diarrhoea, headache, and discomfort in the stomach. Most of these side effects of Grisoclix 500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Grisoclix 500mg Tablet or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Grisoclix 500mg Tablet. Avoid or limit sun exposure while using Grisoclix 500mg Tablet as it may cause photosensitivity reactions (make the skin more sensitive to the sun’s UV rays). Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not take Grisoclix 500mg Tablet if you have porphyria (blood disorder) or liver failure.

Uses of Grisoclix 500mg Tablet

Treatment of Fungal infections of skin, hair and nails.

Medicinal Benefits

Grisoclix 500mg Tablet is an antifungal that is primarily used to treat fungal infections of the skin, nails and hair. Keratin is a protein that is formed in the cells of the skin, hair follicles and nail bed. Grisoclix 500mg Tablet binds to keratin and inhibits the growth and multiplication of fungal cells. Thereby, it prevents newly grown keratin from being infected by fungal cells. The infected keratin dies and sheds from the body, leaving new healthy keratin.

Directions for Use

Take Grisoclix 500mg Tablet with food to avoid stomach upset or as advised by the doctor. Swallow Grisoclix 500mg Tablet as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Grisoclix 500mg Tablet

  • Nausea
  • Diarrhoea
  • Headache
  • Discomfort in the stomach

Drug Warnings

If you are allergic to Griseofulvin or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Grisoclix 500mg Tablet. Avoid or limit sun exposure while using Grisoclix 500mg Tablet as it may cause photosensitivity reactions (make the skin more sensitive to the sun’s UV rays). Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have porphyria (blood disorder), Systemic Lupus Erythematosus (an autoimmune disease) or severe liver disease, inform your doctor before taking Grisoclix 500mg Tablet.

Drug Interactions

Drug-Drug Interaction: Grisoclix 500mg Tablet may interact with certain contraceptives (e.g., etonogestrel, drospirenone, norethindrone), anticoagulants (e.g., Warfarin), and photosensitizing agents (e.g., aminolevulinic acid).

Drug-Food Interaction:  Grisoclix 500mg Tablet may interact with alcohol. Therefore, avoid intake of alcohol as it may increase the risk of adverse effects such as fast heartbeat, increased sweating, flushing or redness of the face.

Drug-Disease Interaction: Do not take Grisoclix 500mg Tablet if you have porphyria (blood disorder) or liver failure. If you have Systemic Lupus Erythematosus (an autoimmune disease) or liver disease, inform your doctor before taking Grisoclix 500mg Tablet.

Drug-Drug Interactions Checker List

  • ETONOGESTREL
  • DROSPIRENONE
  • NORETHINDRONE
  • AMINOLEVULINIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected area of the skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.
  • Avoid sun exposure while using Grisoclix 500mg Tablet as it may make the skin more sensitive to sunlight. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Disease/Condition Glossary

Fungal infection: It is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). Ringworm is a common fungal infection of the skin or scalp that is contagious and causes a rash resembling a worm in a ring shape. Jock itch (also known as tinea cruris) is a fungal infection of the skin that causes an itchy, red rash in warm and moist areas of the body, such as the groin, buttocks, and inner thighs. An athlete’s foot (also known as tinea pedis) is a fungal infection that usually starts between the toes, especially in people who have extremely sweaty feet and wear tight-fitting shoes. It occurs most commonly in athletes. It causes itching, burning, or stinging sensation due to a scaly rash.

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Alcohol

Unsafe

Avoid consumption of alcohol with Grisoclix 500mg Tablet as it may increase the risk of adverse effects such as fast heartbeat, increased sweating, flushing or redness of the face.

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Pregnancy

Unsafe

Grisoclix 500mg Tablet is a Category X pregnancy drug and is unsafe for pregnant women as it may cause harm to the fetus.

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Breast Feeding

Unsafe

Grisoclix 500mg Tablet is excreted in human milk. Therefore, it is not advised for breastfeeding mothers as it may cause adverse effects in the baby.

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Driving

Caution

Grisoclix 500mg Tablet may cause dizziness, drowsiness, lack of coordination or confusion. Therefore, drive only if you alert after taking Grisoclix 500mg Tablet.

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Liver

Caution

Take Grisoclix 500mg Tablet with caution if you have liver disease. However, Grisoclix 500mg Tablet is not recommended for patients suffering from liver failure.

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Kidney

Caution

Take Grisoclix 500mg Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Grisoclix 500mg Tablet is not recommended for children below 2 years. However, for children above 2 years, Grisoclix 500mg Tablet should be used only if advised by a doctor.

Country of origin

India
Other Info - GR27831

Author Details

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FAQs

Grisoclix 500mg Tablet is used to treat fungal infections of the skin like ringworm, jock itch, athlete’s foot, and fungal infections of nails and hair.
You are not recommended to take Grisoclix 500mg Tablet with warfarin as co-administration of these two medicines may change the effects of warfarin. Please consult a doctor if you experience dizziness, unusual bleeding or bruising, blood in urine or stools, vomiting or weakness. Also, contact your doctor before using Grisoclix 500mg Tablet with other medicines so that the dose may be adjusted accordingly.
Grisoclix 500mg Tablet may damage sperm. Therefore, it is not recommended to father a child while taking Grisoclix 500mg Tablet and for 6 months after stopping treatment with Grisoclix 500mg Tablet. It is advised to use effective contraceptive measures during this period to avoid pregnancy.
Grisoclix 500mg Tablet may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn. However, if you notice any unusual sensitivity to the sun like a rash while using Grisoclix 500mg Tablet, please consult a doctor.
You are not recommended to take oral contraceptive pills with Grisoclix 500mg Tablet to prevent pregnancy as it may reduce the effect of oral contraceptive pills. Therefore, you are advised to use other contraceptive methods such as condoms to prevent pregnancy while taking Grisoclix 500mg Tablet, and for 4 weeks (in females) and 6 months (in males) after stopping treatment with Grisoclix 500mg Tablet.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil/surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop using Grisoclix 500mg Tablet without consulting your doctor as it may cause recurring infections. Therefore, take Grisoclix 500mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Grisoclix 500mg Tablet, please consult your doctor.

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