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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:46 PM IST
Grilinctus Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of cough. This medicine works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Common side effects include dry mouth, dry throat or nose, nausea, stomach upset, vomiting, drowsiness, headache, blurred vision, constipation, dizziness, etc.
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Prescription drug

Whats That

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Consult Doctor

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-25

About Grilinctus Syrup

Grilinctus Syrup belongs to a class of medications called 'expectorants' primarily used to treat cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum.

Grilinctus Syrup contains Dextromethorphan, Chlorpheniramine, Guaiphenesin and Ammonium chloride. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough, thereby decreasing the urge to cough. Chlorpheniramine blocks the action of histamine, which is responsible for causing allergic reactions. Guaiphenesin and Ammonium chloride increase the volume of fluid in the airways, reduce the stickiness of mucus and help to remove it from the airways. Together, Grilinctus Syrup helps provides relief from cough.

Your doctor will recommend the dose and duration of Grilinctus Syrup based on your medical condition. Some people may experience dry mouth, dry throat or nose, nausea, stomach upset, vomiting, drowsiness, headache, blurred vision, constipation, dizziness, restlessness or nervousness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or breastfeeding. Grilinctus Syrup is not recommended for children below 12 years of age. Grilinctus Syrup may cause drowsiness, so drive or operate machinery only if you are alert. Avoid alcohol consumption as it may lead to increased drowsiness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Grilinctus Syrup

Treatment of Cough

Medicinal Benefits

Grilinctus Syrup is a combination of four drugs, namely: Dextromethorphan, Chlorpheniramine, Guaiphenesin and Ammonium chloride. Dextromethorphan belongs to the class of cough suppressants; it helps decrease the urge to cough. Chlorpheniramine is an antihistamine (antiallergic drug) that provides relief from symptoms of allergy such as sneezing, stuffy/runny nose, watery eyes, itching, swelling, and congestion or stiffness. Guaifenesin and Ammonium chloride belongs to the class of irritants and expectorants that work by increasing the volume of fluid in the airways, reducing the stickiness of mucus and helps to remove it from the airways. Together, Grilinctus Syrup provides relief from cough.

Side Effects of Grilinctus Syrup

  • Dry mouth
  • Nausea
  • Vomiting
  • Stomach upset
  • Constipation
  • Drowsiness
  • Headache
  • Blurred vision
  • Dizziness
  • Restlessness or nervousness

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Grilinctus Syrup if you are allergic to any of its components. Inform your doctor if you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, lung, heart or urinary problems. 

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Drug-Drug Interactions

verifiedApollotooltip
ChlorpheniraminePotassium chloride
Critical
ChlorpheniraminePotassium citrate
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production.
  • Avoid processed or refined foods. Replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

How Grilinctus Syrup Works

Grilinctus Syrup contains Dextromethorphan, Chlorpheniramine, Guaiphenesin and Ammonium chloride. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough, thereby decreasing the urge to cough. Chlorpheniramine blocks the action of histamine, which is responsible for causing allergic reactions. Guaiphenesin and Ammonium chloride increase the volume of fluid in the airways, reduce the stickiness of mucus and help to remove it from the airways. Together, Grilinctus Syrup helps provides relief from cough.

What if I have taken an overdose of Grilinctus Syrup

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.
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Alcohol

Unsafe

Avoid consumption of alcohol with Grilinctus Syrup as it may increase adverse effects. Please consult a doctor before consuming alcohol with Grilinctus Syrup .

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Pregnancy

Caution

The safety of Grilinctus Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor. Grilinctus Syrup is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Grilinctus Syrup may impair thinking or cause blurred vision or dizziness in some people. Therefore, drive only if you are alert after taking Grilinctus Syrup .

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Liver

Caution

Take Grilinctus Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required if you have severe liver disease.

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Kidney

Caution

Take Grilinctus Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required in severe kidney disease.

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Children

Caution

Grilinctus Syrup is not recommended for children below 12 years of age. Please consult a doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

20, Dr. E. Moses Road, Mahalaxmi, Mumbai - 400 011
Other Info - GRI0002

Author Details

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FAQs

Grilinctus Syrup belongs to a class of medications called 'expectorants' primarily used to treat cough.
Grilinctus Syrup contains Dextromethorphan, Chlorpheniramine, Guaiphenesin and Ammonium chloride. Dextromethorphan blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the urge to cough. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions and helps to provide relief from symptoms of allergy. Guaiphenesin and Ammonium chloride work by increasing the volume of fluid in the airways, reducing the stickiness of mucus and helps to remove it from the airways.
Grilinctus Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Grilinctus Syrup to experience this side effect. However, to avoid dry mouth, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
You should avoid taking Grilinctus Syrup if you have high blood pressure, low blood pressure, breathing difficulty, heart problems (like tachycardia), liver disease, kidney disease and coronary artery diseases. If you have these conditions, contact a doctor before using Grilinctus Syrup .

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