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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Gride-M 850 Tablet is used to treat type 2 diabetes. It contains Glimepiride and Metformin which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Gride-M 850 Tablet

Gride-M 850 Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Gride-M 850 Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Take Gride-M 850 Tablet as prescribed by your doctor. You are advised to take Gride-M 850 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Gride-M 850 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Gride-M 850 Tablet or any other medicines, please tell your doctor. Gride-M 850 Tablet is not recommended for children. Avoid breastfeeding while taking Gride-M 850 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gride-M 850 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Gride-M 850 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Gride-M 850 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Gride-M 850 Tablet .

Uses of Gride-M 850 Tablet

Treatment of Type 2 diabetes mellitus

Directions for Use

Take Gride-M 850 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

Gride-M 850 Tablet contains Glimepiride and Metformin used to treat type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

How Gride-M 850 Tablet Works

Gride-M 850 Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gride-M 850 Tablet

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste

What if I have taken an overdose of Gride-M 850 Tablet

Take Gride-M 850 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypoglycaemia (low blood sugar) and lactic acidosis (buildup of lactic acid in the blood). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Gride-M 850 Tablet or any other medicines, please tell your doctor. Gride-M 850 Tablet is not recommended for children. Avoid breastfeeding while taking Gride-M 850 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gride-M 850 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Gride-M 850 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Gride-M 850 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Gride-M 850 Tablet . Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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GlimepirideSparfloxacin
Severe
GlimepirideNorfloxacin
Severe

Drug-Drug Interactions

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GlimepirideSparfloxacin
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Sparfloxacin with Gride-M 850 Tablet 10's can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideNorfloxacin
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Norfloxacin with Gride-M 850 Tablet 10's may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlimepirideFurosemide
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Furosemide may interfere with blood glucose control and lower the effectiveness of Gride-M 850 Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with furosemide if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideThioridazine
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
When Gride-M 850 Tablet 10's is taken with Thioridazine may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet 10's.

How to manage the interaction:
Taking Gride-M 850 Tablet 10's with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideGatifloxacin
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Taking Gride-M 850 Tablet 10's with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideAmprenavir
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Amprenavir and Gride-M 850 Tablet 10's may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet 10's.

How to manage the interaction:
Although taking Gride-M 850 Tablet 10's and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideLevofloxacin
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Gride-M 850 Tablet 10's with Levofloxacin can affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Levofloxacin with Gride-M 850 Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. Consult the prescriber if you experience dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, or increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideSibutramine
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Taking Gride-M 850 Tablet 10's with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideMoxifloxacin
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Co-administration of Moxifloxacin can affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience headache, dizziness, rapid heartbeat, increased thirst, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideSulfadiazine
Severe
How does the drug interact with Gride-M 850 Tablet 10's:
Taking Gride-M 850 Tablet 10's with Sulfadiazine may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet 10's can be taken with sulfadiazine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Gride-M 850 Tablet Substitute

Substitutes safety advice
  • Glycomet GP 3/850 Tablet 10's

    9.99per tablet
  • Gepride M-3 Tablet 10's

    12.78per tablet
  • Gluconorm-G Plus 3 Tablet 15's

    by AYUR

    15.84per tablet
  • Glimisave M3 850 Tablet 15's

    by AYUR

    11.40per tablet
  • Glitaray M-3 Plus Tablet 15's

    by AYUR

    11.88per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Gride-M 850 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Gride-M 850 Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Gride-M 850 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Gride-M 850 Tablet if you are breastfeeding.

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Driving

Caution

Gride-M 850 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Gride-M 850 Tablet .

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Liver

Caution

Take Gride-M 850 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Gride-M 850 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Gride-M 850 Tablet is not recommended for children as the safety and effectiveness were not established.

FAQs

Gride-M 850 Tablet is indicated in the treatment of type 2 diabetes mellitus.
Gride-M 850 Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
Gride-M 850 Tablet may increase the risk of low blood sugar levels especially with alcohol intake, exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Gride-M 850 Tablet on your own as discontinuing Gride-M 850 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Gride-M 850 Tablet , please consult your doctor so that alternative medicine may be prescribed.
You are not recommended to take Gride-M 850 Tablet with phenytoin as it may reduce the effect of Gride-M 850 Tablet and increase blood sugar levels. However, please consult a doctor before using Gride-M 850 Tablet with other medicines.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
You are advised to take Gride-M 850 Tablet for the duration recommended by the doctor.
Store Gride-M 850 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Gride-M 850 Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Gride-M 850 Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.
Side effects of Gride-M 850 Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Gride-M 850 Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
You are recommended to avoid consumption of alcohol with Gride-M 850 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Gride-M 850 Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Gride-M 850 Tablet . Avoid drinking alcohol.
Other medicines should be taken with Gride-M 850 Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Gride-M 850 Tablet .

Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - GRI0075

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