Gramoneg Oral Suspension is used to treat urinary tract infections (UTIs) caused by bacteria. Urinary tract infection is the most common infection in humans caused by microbes. It can occur in any part of the urinary tract, such as the bladder, urethra, kidneys, or ureters.

Gramoneg Oral Suspension contains Nalixic acid, an antibiotic that works by inhibiting the action of DNA gyrase (a bacterial enzyme), which is essential for repairing and replicating bacteria's genetic material (DNA). Thus, it prevents the reproduction and repair of bacteria. Thus, it kills bacteria and clears the infection.

Take Gramoneg Oral Suspension as prescribed by your doctor. You are advised to take Gramoneg Oral Suspension for as long as your doctor has prescribed it for you based on your medical condition. Sometimes, you may experience diarrhoea, dizziness, headache, nausea, or stomach pain. Most of these side effects of Gramoneg Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Gramoneg Oral Suspension or any other medicines. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gramoneg Oral Suspension. Avoid taking Gramoneg Oral Suspension if you are breastfeeding as it may be excreted in breastmilk and harm the baby. You are recommended to complete the full course of Gramoneg Oral Suspension as your doctor prescribes for effective results. You are advised to maintain a time gap of 2 hours between taking Gramoneg Oral Suspension and mineral supplements, vitamins with minerals or iron, sucralfate, didanosine, or antacids containing magnesium, calcium, and aluminium.

Gramoneg Oral Suspension contains Nalidixic acid, which is a broad-spectrum antibiotic that acts against both gram-positive bacteria and gram-negative bacteria. It is mainly active against gram-negative bacteria such as E-coli, Klebsiella pneumoniae, Enterobacter species, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri and Morganella morganii. Gramoneg Oral Suspension inhibits DNA gyrase (bacterial enzyme) action that is essential for repairing and replicating the genetic material (DNA) of bacteria. Thereby prevents reproduction and repair of bacteria. Thus, kills bacteria and clears the infection.

Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup, dosing syringe, or dropper.

• Diarrhoea
• Dizziness
• Headache
• Nausea
• Stomach pain

If you are allergic to Gramoneg Oral Suspension or any other medicines, please tell your doctor. If you have fits, porphyria (disorder in the formation of red blood pigment), kidney or liver problems, inform your doctor before taking Gramoneg Oral Suspension. If you are pregnant or planning for pregnancy, please inform your doctor before taking Gramoneg Oral Suspension. Avoid taking Gramoneg Oral Suspension if you are breastfeeding as it may be excreted in breastmilk and harm the baby. You are recommended to drink plenty of water to flush out the bacteria. You are recommended to complete the full course of Gramoneg Oral Suspension as prescribed by your doctor for effective results. You are advised to maintain a time gap of 2 hours between taking Gramoneg Oral Suspension and mineral supplements, vitamins with minerals or iron, sucralfate, didanosine, or antacids containing magnesium, calcium, and aluminium.

Drug-Drug Interactions: Gramoneg Oral Suspension may interact with a blood thinner (warfarin), bronchodilator (theophylline), antibiotics (tetracycline, chloramphenicol, nitrofurantoin), high uric acid levels lowering medicine (probenecid), anticancer drug (melphalan), immunosuppressant (cyclosporine).

Drug-Food Interactions: Gramoneg Oral Suspension may interact with caffeine. Therefore, avoid caffeine intake with Gramoneg Oral Suspension as it may increase the effects of caffeine.

Drug-Disease Interactions: If you have fits, porphyria (a disorder in the formation of red blood pigment), or liver or kidney problems, inform your doctor before taking Gramoneg Oral Suspension.

• WARFARIN
• THEOPHYLLINE
• TETRACYCLINE
• CHLORAMPHENICOL
• NITROFURANTOIN
• PROBENECID
• CYCLOSPORINE
• MELPHALAN

• Avoid alcohol, soda, coffee, tea, and artificial sweeteners, as they may cause bladder irritation.
• Drink plenty of water or other fluids daily while taking Gramoneg Oral Suspension to flush out the bacteria.
• Avoid spicy foods and citrus fruits (lemons, oranges, grapefruits) as they may irritate the bladder.
• Eat foods antioxidant-rich foods such as blueberries, cranberries, tomatoes, spinach, broccoli, and plain Greek yoghurt.
• Take probiotics after completing the entire course of Gramoneg Oral Suspension to restore some good bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
• Include fibre-rich foods, which can be easily digested by your gut bacteria and help stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.

• If Gramoneg Oral Suspension is continued for more than 2 weeks, blood tests are recommended periodically to monitor blood counts and kidney and liver function.

Urinary tract infection (UTI): It is the most common infection in humans caused by microbes and can occur in any part of the urinary tract such as the bladder, urethra, kidneys, or ureters. Most urinary tract infections are caused by bacteria, but some may be caused by fungi and rarely by viruses. Generally, urinary tract infections involve the bladder and urethra in the lower tract. It occurs mostly in women than in men. The symptoms of lower tract (bladder, urethra) infection include the increased urge to urinate, bloody urine, pain with urination, or pelvic pain in women. The symptoms of upper tract (kidneys, ureters) infection include vomiting, nausea, fever, or back pain.