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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Grafalon 5Ml Inj is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation. It contains Antithymocyte immunoglobulin, which lowers specific cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

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Prescription drug

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Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Grafalon 5Ml Inj

Grafalon 5Ml Inj belongs to the group of medicines called immunosuppressants indicated for the prevention and treatment of acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation.

Grafalon 5Ml Inj contains antithymocyte immunoglobulin, which works by preventing the white blood cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

In some cases, Grafalon 5Ml Inj may cause side effects such as fever, chills, low white blood cell count, low platelet count, blood clotting problems, and skin rash. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Grafalon 5Ml Inj. Consult the doctor Grafalon 5Ml Inj if you are pregnant. Avoid breastfeeding during treatment. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Grafalon 5Ml Inj

Prevention and treatment of Kidney transplant rejection and aplastic anaemia

Directions for Use

Grafalon 5Ml Inj will be administered by a healthcare professional; do not self-administer. It should only be used by physicians experienced in immunosuppressive therapy to treat kidney transplant patients.

Medicinal Benefits

Grafalon 5Ml Inj belongs to the group of medicines called immunosuppressants indicated for preventing and treating acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation. Grafalon 5Ml Inj contains Antithymocyte immunoglobulin, which lowers certain cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

How Grafalon 5Ml Inj Works

Grafalon 5Ml Inj contains antithymocyte immunoglobulin, which works by preventing the white blood cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Grafalon 5Ml Inj

  • Fever
  • Chills
  • Low white blood cell count
  • Low platelet count
  • Blood clotting problems
  • Skin rash

What if I have taken an overdose of Grafalon 5Ml Inj

As Grafalon 5Ml Inj is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not use Grafalon 5Ml Inj if you are allergic to any of its components. Inform the doctor if you have any active infection. Consult the doctor if you are pregnant or think you may be pregnant. Avoid/discontinue breastfeeding during treatment with Grafalon 5Ml Inj. Seek medical attention if you experience symptoms of cytokine release syndrome (fever, chills, headache, chest pain, low blood pressure, shortness of breath, fast breathing, and swelling), infusion-associated reactions (generalised rash, fast heart rate, shortness of breath, and low blood pressure), or serum sickness (rash, joint pain, fever, chills, and pain). Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
Antithymocyte GlobulinClozapine
Severe
Antithymocyte GlobulinEtanercept
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS
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Alcohol

Consult your doctor

It is not known if alcohol affects Grafalon 5Ml Inj. Please consult your doctor.

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Pregnancy

Caution

Consult the doctor if you are pregnant, think you may be pregnant or are planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Grafalon 5Ml Inj. Seek medical advice before taking this medicine if you want to breastfeed your child.

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Driving

Caution

Do not drive or operate heavy machinery after the treatment with Grafalon 5Ml Inj as it may cause side effects. ask your doctor for more information.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Grafalon 5Ml Inj.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Grafalon 5Ml Inj.

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Children

Consult your doctor

Information about the use of Grafalon 5Ml Inj in children is limited. Consult the doctor if you have any concerns.

FAQs

Grafalon 5Ml Inj is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation.
Grafalon 5Ml Inj helps to stop your body's immune system from rejecting the new kidney.
Due to immunosuppressive effects, infections have been reported during treatment with Grafalon 5Ml Inj. Careful patient monitoring and appropriate anti-infective prophylaxis are recommended. Consult the doctor immediately if you notice signs of infections such as fever, chills, pale skin, shortness of breath, tiredness, or mouth sores.
Concomitant use of Grafalon 5Ml Inj with live vaccines is not advised, as live vaccines may interfere with Grafalon 5Ml Inj treatment. Talk to the doctor if you are undergoing any vaccination.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - GRA0243

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