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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Gonablok 50 mg Capsule is used to treat endometriosis and breast cysts. It contains Danazol which works by decreasing the amount of oestrogen in the body and shrinks the tissue or stops its growth. In some cases, this medicine may cause side effects such as sore throat, hoarse voice, hair loss, excessive hair growth on the body or face, and stomach pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

DANAZOL-50MG

Manufacturer/Marketer

Win Medicare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Gonablok 50 mg Capsule

Gonablok 50 mg Capsule belongs to the class of drugs called synthetic steroids used to treat endometriosis and breast cysts. Endometriosis is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Gonablok 50 mg Capsule contains Danazol which works by suppressing the activity of ovaries. Thus, it decreases the amount of estrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

Take Gonablok 50 mg Capsule as prescribed by your doctor. You are advised to take Gonablok 50 mg Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience sore throat, hoarse voice, hair loss, excessive hair growth on the body or face, stomach pain, skin rashes, or chest pain. Most of these side effects of Gonablok 50 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Gonablok 50 mg Capsule or any other medicines, please tell your doctor. Gonablok 50 mg Capsule is contraindicated in pregnant and breastfeeding women. You are recommended to avoid or limit consumption of alcohol with Gonablok 50 mg Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Gonablok 50 mg Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Gonablok 50 mg Capsule as it may increase the effect of certain anesthetics.

Uses of Gonablok 50 mg Capsule

Treatment of Endometriosis, Breast lumps

Medicinal Benefits

Gonablok 50 mg Capsule contains Danazol which decreases the amount of estrogen in the body by suppressing the activity of ovaries. Thus, Gonablok 50 mg Capsule induces temporary menopause and shrinks the tissue outside the uterus or stops its growth. Also, Gonablok 50 mg Capsule works by inhibiting the release of hormones in the body that cause breast pain and lumps.

Directions for Use

Take Gonablok 50 mg Capsule with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gonablok 50 mg Capsule

  • Sore throat
  • Hoarse voice
  • Hair loss
  • Excessive hair growth on body or face
  • Stomach pain
  • Skin rashes
  • Chest pain

Drug Warnings

If you are allergic to Gonablok 50 mg Capsule or any other medicines, please tell your doctor. Gonablok 50 mg Capsule is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives to avoid pregnancy while taking Gonablok 50 mg Capsule as it may cause birth defects. You are recommended to avoid or limit consumption of alcohol with Gonablok 50 mg Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Gonablok 50 mg Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Gonablok 50 mg Capsule as it may increase the effect of certain anesthetics. If you have pain while moving your legs or arms, stop taking Gonablok 50 mg Capsule and consult a doctor immediately as this might be due to a blood clot.

Drug Interactions

Drug-Drug Interaction: Gonablok 50 mg Capsule may interact with blood thinners (warfarin), immunosuppressants (tacrolimus, ciclosporin), cholesterol-lowering medicines (simvastatin), medicines used to treat vitamin D deficiency (alfacalcidol), steroid hormones (progesterone, testosterone, estrogen).

Drug-Food Interaction: Gonablok 50 mg Capsule may interact with alcohol. Therefore, avoid or limit consumption of alcohol with Gonablok 50 mg Capsule as it may cause shortness of breath or make you feel sick.

Drug-Disease Interaction: If you have porphyria (a blood disorder), unusual vaginal bleeding, blood clots, liver, kidney or heart disease, high blood pressure, polycythemia (blood gets thicker), fits, diabetes, lipid disorders (blood fat problems), migraine or cancer, inform your doctor before taking Gonablok 50 mg Capsule .

Drug-Drug Interactions Checker List

  • WARFARIN
  • TACROLIMUS
  • CICLOSPORIN
  • SIMVASTATIN
  • ALFACALCIDOL
  • PROGESTERONE
  • TESTOSTERONE
  • ESTROGEN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Special Advise

  • If you are supposed to take Gonablok 50 mg Capsule for more than 6 months, your doctor may recommend an ultrasound test to check your liver condition.
  • Regular blood tests are recommended while taking Gonablok 50 mg Capsule to monitor liver functioning and blood levels.
  • Gonablok 50 mg Capsule may affect the results of certain blood tests used to check liver and thyroid function, hormone testosterone levels, sugars, fats, and protein levels in the blood. Therefore, inform your doctor that you are taking Gonablok 50 mg Capsule before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse or discomfort with bowel movements. 

Breast cysts (lumps): These lumps are non-cancerous but may be painful. Breast lumps may be caused due to milk cysts (sacs filled with milk) that may occur during breastfeeding, fibrocystic breasts (breast tissue feels lumpy), injury or mastitis (infection of breast).

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Alcohol

Unsafe

Avoid or limit alcohol consumption with Gonablok 50 mg Capsule as it may cause shortness of breath or make you feel sick.

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Pregnancy

Unsafe

Gonablok 50 mg Capsule is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Gonablok 50 mg Capsule is contraindicated in breastfeeding women as small amounts of Gonablok 50 mg Capsule may be excreted in breast milk. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Gonablok 50 mg Capsule may cause dizziness, vertigo (spinning feeling) or blurred vision. Therefore, avoid driving if you experience any of these symptoms after taking Gonablok 50 mg Capsule .

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Liver

Caution

Take Gonablok 50 mg Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Gonablok 50 mg Capsule if you have severe liver disease.

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Kidney

Caution

Take Gonablok 50 mg Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Gonablok 50 mg Capsule if you have severe kidney disease.

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Children

Caution

Please consult a doctor regarding the use of Gonablok 50 mg Capsule in children.

Country of origin

India

Manufacturer/Marketer address

1309, 14th Floor, Madi Tower, 98, Nehru Place, New Delhi, Delhi 110019
Other Info - GON0003

Author Details

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FAQs

Gonablok 50 mg Capsule contains Danazol that works by suppressing the activity of ovaries. Thus, it decreases the amount of oestrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.
You are not recommended to use a contraceptive pill with Gonablok 50 mg Capsule as it may decrease the effectiveness of hormonal contraceptives. Therefore, it is advised to use effective non-hormonal contraceptives such as Intra-Uterine Device or barrier method in conjunction with contraceptive jelly or foam. However, please consult a doctor if you have any concerns regarding this.
Gonablok 50 mg Capsule may be used to treat breast lumps when other treatments have not worked. Gonablok 50 mg Capsule inhibits the release of hormones in the body that cause breast pain and lumps.
Gonablok 50 mg Capsule may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Gonablok 50 mg Capsule and inform your doctor if you have diabetes before taking Gonablok 50 mg Capsule .
You are not recommended to take Gonablok 50 mg Capsule with simvastatin as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking Gonablok 50 mg Capsule with other medicines.
Gonablok 50 mg Capsule is not recommended for patients suffering from severe liver disease as it may worsen the condition. Therefore, inform your doctor if you have any liver disease before taking Gonablok 50 mg Capsule .
Gonablok 50 mg Capsule is used to treat endometriosis (tissue lining the uterus grows outside the uterus) and breast cysts.
Gonablok 50 mg Capsule may cause side effects such as hoarse voice, sore throat, stomach pain, hair loss, skin rashes, chest pain and excessive hair growth on face or body. If these side effects persist or worsen, please consult your doctor.

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