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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:36 PM IST
Gole L 75mg/20mg Tablet SR is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. It contains Rabeprazole and Levosulpiride which work by blocking acid production and preventing the backflow of food and acid into the mouth. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Gladcare Formulations Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Gole L 75mg/20mg Tablet SR

Gole L 75mg/20mg Tablet SR is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Gole L 75mg/20mg Tablet SR is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Gole L 75mg/20mg Tablet SR helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Gole L 75mg/20mg Tablet SR for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Gole L 75mg/20mg Tablet SR may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Gole L 75mg/20mg Tablet SR may cause drowsiness and dizziness, so drive only if you are alert. Gole L 75mg/20mg Tablet SR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Gole L 75mg/20mg Tablet SR as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Gole L 75mg/20mg Tablet SR

Treatment of Gastro-oesophageal reflux disease, acidity, indigestion, heartburn, and peptic ulcers.

Medicinal Benefits

Gole L 75mg/20mg Tablet SR is a combination of two drugs: Rabeprazole and Levosulpiride. Gole L 75mg/20mg Tablet SR belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Gole L 75mg/20mg Tablet SR helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

Directions for Use

Take Gole L 75mg/20mg Tablet SR 1 hour prior to food. Swallow Gole L 75mg/20mg Tablet SR as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gole L 75mg/20mg Tablet SR

  • Headache
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Dizziness
  • Diarrhoea 

Drug Warnings

Do not take Gole L 75mg/20mg Tablet SR if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Gole L 75mg/20mg Tablet SR may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Gole L 75mg/20mg Tablet SR may cause dizziness and drowsiness, so drive only if you are alert. Gole L 75mg/20mg Tablet SR is not recommended for children as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Gole L 75mg/20mg Tablet SR may interact with a blood thinner (warfarin), anti-cancer (methotrexate), cardiac glycoside (digoxin), immunosuppressant (mycophenolate mofetil, tacrolimus), antibiotic (amoxicillin, clarithromycin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have gastrointestinal bleeding, intestinal obstruction, epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), hyperprolactinemia (high levels of prolactin), bone fractures, or hypomagnesemia (low levels of magnesium).

Drug-Drug Interactions Checker List

  • WARFARIN
  • METHOTREXATE
  • DIGOXIN
  • MYCOPHENOLATE MOFETIL
  • TACROLIMUS
  • AMOXICILLIN
  • CLARITHROMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating to prevent acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practice relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Special Advise

  • Gole L 75mg/20mg Tablet SR might cause false-positive results for secretin stimulation test, prolactin test, and tests for tetrahydrocannabinol (THC). Inform the person doing the tests that you are taking Gole L 75mg/20mg Tablet SR.

  • Regular blood tests for monitoring magnesium levels and bone density tests are advised if you are on long-term treatment with Gole L 75mg/20mg Tablet SR.

  • Inform your doctor if you are due to have Chromogranin A test.

Disease/Condition Glossary

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn, and peptic ulcers.

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. 

Stomach ulcers: Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea, and vomiting.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gole L 75mg/20mg Tablet SR. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Gole L 75mg/20mg Tablet SR may pass into breast milk. Consult your doctor if you are breastfeeding; your doctor will decide whether Gole L 75mg/20mg Tablet SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Gole L 75mg/20mg Tablet SR may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Gole L 75mg/20mg Tablet SR should not be given to children as the safety and effectiveness were not established.

Country of origin

India
Other Info - GO69147

Author Details

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FAQs

Gole L 75mg/20mg Tablet SR is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers.
Gole L 75mg/20mg Tablet SR contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents the backflow of food and acid into the mouth. Together, Gole L 75mg/20mg Tablet SR helps in providing relief from acidity.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Gole L 75mg/20mg Tablet SR contains rabeprazole which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of Gole L 75mg/20mg Tablet SR for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.
Dry mouth could be a side-effect of Gole L 75mg/20mg Tablet SR. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.
Do not take Gole L 75mg/20mg Tablet SR for longer durations unless prescribed by the doctor. Gole L 75mg/20mg Tablet SR might cause bone problems and hypomagnesemia on long-term treatment. Talk to your doctor if you do not find symptomatic relief despite taking Gole L 75mg/20mg Tablet SR for 2 weeks.
Gole L 75mg/20mg Tablet SR might cause irregular periods/abnormal menstruation. Consult your doctor if you notice abnormal bleeding patterns.
Avoid consuming alcohol along with Gole L 75mg/20mg Tablet SR as it could lead to increased drowsiness and elevate stomach acid production.
If you're experiencing frequent heartburn and stomach pain while taking Gole L 75mg/20mg Tablet SR, it's essential to consult with your doctor. They can assess your specific situation and provide the best course of action.
Gole L 75mg/20mg Tablet SR is typically used to treat excessive stomach acid production conditions. It's essential to consult with a healthcare professional to determine if Gole L 75mg/20mg Tablet SR is appropriate for your specific condition. They can assess your symptoms, medical history, and other factors to provide personalized guidance.
The best time to take Gole L 75mg/20mg Tablet SR depends on your doctor's specific instructions. However, a common recommendation is to take it before breakfast. This helps the medication effectively reduce stomach acid production throughout the day.
Gole L 75mg/20mg Tablet SR is more often used to treat gastrointestinal disorders. However, its use may be contraindicated in individuals with allergies to either the drug or its excipients, pregnant or breastfeeding women, those with gastrointestinal bleeding or obstruction, severe kidney or liver impairment, and individuals with certain medical conditions. Before using Gole L 75mg/20mg Tablet SR, it's essential to consult with a healthcare professional to assess your individual situation and determine if it's safe for you.
Gole L 75mg/20mg Tablet SR combines two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent).
The safety of Gole L 75mg/20mg Tablet SR during pregnancy and breastfeeding has not been fully established. If you are pregnant or breastfeeding, it's essential to discuss the risks and benefits of taking Gole L 75mg/20mg Tablet SR with your doctor.
Yes, dizziness can be a side effect of taking Gole L 75mg/20mg Tablet SR.
No definitive evidence suggests that using Gole L 75mg/20mg Tablet SR increases the risk of fractures. If you have concerns about your risk of fractures, it's best to discuss them with your doctor. They can assess your individual situation and provide appropriate advice.
Gole L 75mg/20mg Tablet SR may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.
It's always best to follow the specific storage and disposal instructions provided on the medication packaging or by your pharmacist. If you have any questions or concerns, don't hesitate to ask your healthcare provider.
Common side effects of Gole L 75mg/20mg Tablet SR may include headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

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