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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Glucan-PG2 Tablet is used to treat type 2 diabetes. It works by reducing sugar production in the liver, delaying sugar absorption from the intestines, and removing sugar from the blood. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Lucan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Glucan-PG2 Tablet

Glucan-PG2 Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance).

Glucan-PG2 Tablet is a combination of three antidiabetic drugs, namely: Glimepiride, Metformin, and Pioglitazone. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Glucan-PG2 Tablet helps to control blood sugar levels.

Take Glucan-PG2 Tablet as prescribed by your doctor. You are advised to take Glucan-PG2 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. Most of these side effects of Glucan-PG2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Glucan-PG2 Tablet or any other medicines, please tell your doctor. Glucan-PG2 Tablet is not recommended for children. Avoid breastfeeding while taking Glucan-PG2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glucan-PG2 Tablet as it may harm the unborn baby. Glucan-PG2 Tablet should be used with caution in elderly patients. Avoid alcohol consumption with Glucan-PG2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glucan-PG2 Tablet .

Uses of Glucan-PG2 Tablet

Treatment of Type 2 diabetes mellitus

Medicinal Benefits

Glucan-PG2 Tablet contains three antidiabetic drugs (Glimepiride, Metformin and Voglibose) used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin reduces the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produces insulin. Thereby, Glucan-PG2 Tablet helps to control blood sugar levels.

Side Effects of Glucan-PG2 Tablet

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste
  • Low blood sugar

Directions for Use

Take Glucan-PG2 Tablet with food to avoid stomach upset, or take it as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Glucan-PG2 Tablet or any other medicines, please tell your doctor. Glucan-PG2 Tablet is not recommended for children. Avoid breastfeeding while taking Glucan-PG2 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glucan-PG2 Tablet as it may harm the unborn baby. Glucan-PG2 Tablet should be used with caution in elderly patients. Avoid alcohol consumption with Glucan-PG2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glucan-PG2 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Glucan-PG2 Tablet . Beware of symptoms of hypoglycemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Therapeutic Class

ANTIDIABETICS

Drug-Drug Interactions

verifiedApollotooltip
MetforminIopromide
Critical
MetforminIopamidol
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low fat and a low sugar diet. Replace carbohydrates-containing foods with whole grains, fruits and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

What if I have taken an overdose of Glucan-PG2 Tablet

Take Glucan-PG2 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include loss of consciousness, lactic acidosis (buildup of lactic acid in the blood), and pancreatitis (inflammation of the pancreas). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glucan-PG2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glucan-PG2 Tablet is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glucan-PG2 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glucan-PG2 Tablet if you are breastfeeding.

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Driving

Caution

Glucan-PG2 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glucan-PG2 Tablet .

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Liver

Caution

Take Glucan-PG2 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glucan-PG2 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glucan-PG2 Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

A-43, G/F, Kh No 115, Khirki Ext. Panchsheel Vihar, Delhi-110817, India
Other Info - GLU0694

Author Details

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FAQs

Glucan-PG2 Tablet is used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone.
Glucan-PG2 Tablet contains Glimepiride, Metformin and Pioglitazone. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Pioglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Glucan-PG2 Tablet helps to control blood sugar levels.
Glucan-PG2 Tablet may increase the risk of low blood sugar levels especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
You are not recommended to take Glucan-PG2 Tablet with pregabalin as it may cause weight gain and fluid retention that could lead to heart failure. However, please consult a doctor before using Glucan-PG2 Tablet with other medicines.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Glucan-PG2 Tablet on your own as discontinuing Glucan-PG2 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glucan-PG2 Tablet , please consult your doctor so that alternative medicine may be prescribed.
Yes, Glucan-PG2 Tablet may cause stomach upset as a side effect. Drink water/fluids in small, frequent amounts and chew the food properly while eating.
You are recommended to avoid consumption of alcohol with Glucan-PG2 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Inform the doctor if you are taking any other medicines, have any other medical conditions, and if you are pregnant or breastfeeding.
Yes, Glucan-PG2 Tablet may lead to vitamin B12 deficiency, particularly on long-term use. Consult the doctor if you experience symptoms of vitamin b12 deficiency such as headache, loss of appetite, fatigue, mental impairment, pins and needle sensation, and pale skin.
Store Glucan-PG2 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glucan-PG2 Tablet may cause side effects like stomach pain, nausea, diarrhoea, vomiting, headache, metallic taste, or low blood sugar. If the side effects persist or worsen, please consult your doctor.

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