Globrim 0.15% Eye Drop belongs to the class of alpha-adrenergic agonists, used alone or in combination with other medicines to lower increased eye pressure in conditions such as ocular hypertension and glaucoma. Glaucoma is an eye disease in which the optic nerve is damaged. This damaged nerve leads to an increase in eye pressure abnormally and can lead to permanent vision loss.

Globrim 0.15% Eye Drop contains Brimonidine that works by decreasing the production of aqueous humour (fluid in the eye). Thereby, Globrim 0.15% Eye Drop helps in reducing eye pressure.

Globrim 0.15% Eye Drop is for ophthalmic use only. In some cases, Globrim 0.15% Eye Drop may cause common side effects such as watery eyes, irritation, abnormal taste, and abnormal vision. Most of these side effects of Globrim 0.15% Eye Drop are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You are not recommended to stop using Globrim 0.15% Eye Drop abruptly as it may increase eye pressure. Globrim 0.15% Eye Drop is not recommended for children below 17 years as safety has not been established. Avoid alcohol consumption while using Globrim 0.15% Eye Drop. Consult your doctor if you are pregnant or planning for pregnancy before starting Globrim 0.15% Eye Drop. Globrim 0.15% Eye Drop may cause drowsiness, blurred vision or abnormal vision, so drive only if you are alert.

Globrim 0.15% Eye Drop contains Brimonidone which is primarily used in treating increased pressure of the eye in conditions such as glaucoma and ocular hypertension. Globrim 0.15% Eye Drop works by decreasing the production of aqueous humour (fluid in the eye) and reducing eye pressure.

• Watery eyes
• Irritation
• Itchy eyes
• Abnormal vision 

Do not use Globrim 0.15% Eye Drop if you are allergic to any of its ingredients, if you are taking tricyclic antidepressants or monoamine oxidase inhibitors (MAOIs), or if you are breastfeeding. Inform your doctor if you have/had depression, heart problems, light-headedness, reduced mental capacity, lowered blood supply to the brain, blood vessel disease, poor blood circulation problems, or liver/kidney problems. Globrim 0.15% Eye Drop is not recommended for children below 17years as the safety has not been established. Avoid alcohol consumption while using Globrim 0.15% Eye Drop. Consult your doctor if you are pregnant or planning for pregnancy before starting Globrim 0.15% Eye Drop. Globrim 0.15% Eye Drop may cause drowsiness, blurred vision or abnormal vision, so drive only if you are alert.

Drug-Drug Interactions: Globrim 0.15% Eye Drop may have an interaction with monoamine oxidase inhibitor (isocarboxazid, phenelzine, selegiline, tranylcypromine), antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, trimipramine), barbiturates (phenobarbital, secobarbital), heart disease medications (digoxin), medicines for mental illness ( chlorpromazine, methylphenidate, reserpine), anti-hypertensives (metoprolol, atorvastatin), and diuretics (furosemide).

Drug-Food Interactions:  Alcohol, if taken along with Globrim 0.15% Eye Drop, is known to cause excessive drowsiness and sleepiness. Therefore, avoid alcohol consumption while using Globrim 0.15% Eye Drop.

Drug-Disease Interactions: Inform your doctor if you have or ever had depression, cornea problems, liver or kidney disease, heart problems, or poor blood circulation problems. 

• ISOCARBOXAZID
• PHENELZINE
• SELEGILINE
• AMITRIPTYLINE
• CLOMIPRAMINE
• DOXEPIN
• IMIPRAMINE
• NORTRIPTYLINE
• PHENOBARBITAL
• DIGOXIN
• CHLORPROMAZINE
• METHYLPHENIDATE
• RESERPINE
• METOPROLOL
• ATORVASTATIN
• FUROSEMIDE
• TRANYLCYPROMINE
• DESIPRAMINE
• AMOXAPINE
• PROTRIPTYLINE
• TRIMIPRAMINE
• SECOBARBITAL

• Avoid intake of baked foods such as cakes, cookies, doughnuts, or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage optic nerve.
• Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
• Avoid exercises such as any position where the head is lower than the body as an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients. 

Glaucoma: Glaucoma is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms of glaucoma initially except the slow loss of vision gradually. However, some symptoms include visible rainbow-coloured circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance, or nausea.

Ocular hypertension: Ocular hypertension is a condition caused due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). This leads to the build-up of excess fluid in the eye resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.