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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Glimsafe 2MF Tablet is used to treat type 2 diabetes. It contains Glimepiride and Metformin which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer :

Beats Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Glimsafe 2MF Tablet

Glimsafe 2MF Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Glimsafe 2MF Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Take Glimsafe 2MF Tablet as prescribed by your doctor. You are advised to take Glimsafe 2MF Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Glimsafe 2MF Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Glimsafe 2MF Tablet or any other medicines, please tell your doctor. Glimsafe 2MF Tablet is not recommended for children. Avoid breastfeeding while taking Glimsafe 2MF Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glimsafe 2MF Tablet as it may harm the unborn baby. Avoid alcohol consumption with Glimsafe 2MF Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glimsafe 2MF Tablet . Take short, frequent meals and avoid prolonged fasting while taking Glimsafe 2MF Tablet .

Uses of Glimsafe 2MF Tablet

Treatment of Type 2 diabetes mellitus

Directions for Use

Take Glimsafe 2MF Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

Glimsafe 2MF Tablet contains Glimepiride and Metformin used to treat type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

How Glimsafe 2MF Tablet Works

Glimsafe 2MF Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Glimsafe 2MF Tablet

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste

What if I have taken an overdose of Glimsafe 2MF Tablet

Take Glimsafe 2MF Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include hypoglycaemia (low blood sugar) and lactic acidosis (buildup of lactic acid in the blood). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Glimsafe 2MF Tablet or any other medicines, please tell your doctor. Glimsafe 2MF Tablet is not recommended for children. Avoid breastfeeding while taking Glimsafe 2MF Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glimsafe 2MF Tablet as it may harm the unborn baby. Avoid alcohol consumption with Glimsafe 2MF Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glimsafe 2MF Tablet . Take short, frequent meals and avoid prolonged fasting while taking Glimsafe 2MF Tablet . Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug-Drug Interactions

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GlimepirideVoriconazole
Severe
GlimepirideOfloxacin
Severe

Drug-Drug Interactions

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GlimepirideVoriconazole
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Glimsafe 2MF Tablet 10's with Voriconazole may increase the blood levels and effects of Glimsafe 2MF Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Glimsafe 2MF Tablet 10's can be taken with voriconazole if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideOfloxacin
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Ofloxacin and Glimsafe 2MF Tablet 10's can sometimes have an effect on blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Glimsafe 2MF Tablet 10's can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweat, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Keep an eye on your blood glucose level. Do not discontinue any medications without consulting a doctor.
GlimepirideDiethylstilbestrol
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Diethylstilbestrol may interfere with blood glucose control and reduce the effectiveness of Glimsafe 2MF Tablet 10's.

How to manage the interaction:
Although there is a possible interaction between Glimsafe 2MF Tablet 10's and Diethylstilbestrol, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideAmprenavir
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Amprenavir and Glimsafe 2MF Tablet 10's may interfere with blood glucose control and reduce the effectiveness of Glimsafe 2MF Tablet 10's.

How to manage the interaction:
Although taking Glimsafe 2MF Tablet 10's and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideFluconazole
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Fluconazole may increase the blood levels and effects of Glimsafe 2MF Tablet 10's may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Glimsafe 2MF Tablet 10's can be taken with fluconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideAminolevulinic acid
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Aminolevulinic acid sensitizes your skin to bright lights and combining it with other medications that can also have this effect (i.e., photosensitivity) such as Glimsafe 2MF Tablet 10's may increase the risk of a severe sunburn.

How to manage the interaction:
Taking Glimsafe 2MF Tablet 10's with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideCitalopram
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Taking Glimsafe 2MF Tablet 10's with Citalopram may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Glimsafe 2MF Tablet 10's can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideMiconazole
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Miconazole with Glimsafe 2MF Tablet 10's may increase the blood levels and effects of Glimsafe 2MF Tablet 10's leading to low blood glucose levels.

How to manage the interaction:
Although there is a possible interaction between Miconazole and Glimsafe 2MF Tablet 10's, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat Consult a doctor immediately. Do not stop using medications without a doctor's advice.
GlimepirideThioridazine
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
When Glimsafe 2MF Tablet 10's is taken with Thioridazine may interfere with blood glucose control and reduce the effectiveness of Glimsafe 2MF Tablet 10's.

How to manage the interaction:
Taking Glimsafe 2MF Tablet 10's with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideFurosemide
Severe
How does the drug interact with Glimsafe 2MF Tablet 10's:
Co-administration of Furosemide may interfere with blood glucose control and lower the effectiveness of Glimsafe 2MF Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Glimsafe 2MF Tablet 10's can be taken with furosemide if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Glimsafe 2MF Tablet Substitute

Substitutes safety advice
  • Auglimy M2 Tablet 10's

    11.40per tablet
  • Gluconorm G 2 Tablet 15's

    19.02per tablet
  • Glycomet-GP 2 Tablet 15's

    10.71per tablet
  • Gemer 2 Tablet 15's

    13.86per tablet
  • Amaryl M 2 mg Tablets 20's

    by AYUR

    19.78per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimsafe 2MF Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimsafe 2MF Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimsafe 2MF Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimsafe 2MF Tablet if you are breastfeeding.

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Driving

Caution

Glimsafe 2MF Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimsafe 2MF Tablet .

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Liver

Caution

Take Glimsafe 2MF Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimsafe 2MF Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimsafe 2MF Tablet is not recommended for children as the safety and effectiveness were not established.

FAQs

Glimsafe 2MF Tablet is indicated in the treatment of type 2 diabetes mellitus.
Glimsafe 2MF Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
Glimsafe 2MF Tablet may increase the risk of low blood sugar levels especially with alcohol intake, exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Glimsafe 2MF Tablet on your own as discontinuing Glimsafe 2MF Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimsafe 2MF Tablet , please consult your doctor so that alternative medicine may be prescribed.
You are not recommended to take Glimsafe 2MF Tablet with phenytoin as it may reduce the effect of Glimsafe 2MF Tablet and increase blood sugar levels. However, please consult a doctor before using Glimsafe 2MF Tablet with other medicines.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
You are advised to take Glimsafe 2MF Tablet for the duration recommended by the doctor.
Store Glimsafe 2MF Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glimsafe 2MF Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Glimsafe 2MF Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.
Side effects of Glimsafe 2MF Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Glimsafe 2MF Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
You are recommended to avoid consumption of alcohol with Glimsafe 2MF Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Glimsafe 2MF Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimsafe 2MF Tablet . Avoid drinking alcohol.
Other medicines should be taken with Glimsafe 2MF Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glimsafe 2MF Tablet .

Country of origin

India

Manufacturer/Marketer address

no.121,ii nd floor,alwarpet street alwarprt chennai chennai tn 600018 in
Other Info - GLI0536

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