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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:58 AM IST

Glimicid-M1 Tablet is used to treat type 2 diabetes. It contains Glimepiride and Metformin which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently. In some cases, this medicine may cause side effects such as stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE

Manufacturer/Marketer

Brigade Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Glimicid-M1 Tablet

Glimicid-M1 Tablet belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Glimicid-M1 Tablet is a combination of two antidiabetic drugs, namely: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Take Glimicid-M1 Tablet as prescribed by your doctor. You are advised to take Glimicid-M1 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects of Glimicid-M1 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Glimicid-M1 Tablet or any other medicines, please tell your doctor. Glimicid-M1 Tablet is not recommended for children. Avoid breastfeeding while taking Glimicid-M1 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glimicid-M1 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Glimicid-M1 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glimicid-M1 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Glimicid-M1 Tablet .

Uses of Glimicid-M1 Tablet

Treatment of Type 2 diabetes mellitus

Medicinal Benefits

Glimicid-M1 Tablet contains Glimepiride and Metformin used to treat type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin, which helps remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin, which enables these cells to remove sugar more effectively from the blood.

Directions for Use

Take Glimicid-M1 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Glimicid-M1 Tablet

  • Stomach pain
  • Nausea
  • Diarrhoea
  • Vomiting
  • Headache
  • Metallic taste

Drug Warnings

If you are allergic to Glimicid-M1 Tablet or any other medicines, please tell your doctor. Glimicid-M1 Tablet is not recommended for children. Avoid breastfeeding while taking Glimicid-M1 Tablet as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glimicid-M1 Tablet as it may harm the unborn baby. Avoid alcohol consumption with Glimicid-M1 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glimicid-M1 Tablet . Take short, frequent meals and avoid prolonged fasting while taking Glimicid-M1 Tablet . Beware of symptoms of hypoglycemia (low blood sugar), which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also consult your doctor. Make sure to carry these with you at all times, especially during long travels.

Drug Interactions

Drug-Drug Interaction: Glimicid-M1 Tablet may have interaction with antibiotics (rifampicin, trimethoprim), calcium channel blockers (verapamil), antacids (cimetidine), HIV/AIDS drugs (dolutegravir), heart-related medicine (ranolazine), anticancer drugs (vandetanib, crizotinib, olaparib), antifungals (fluconazole, miconazole), water pill (acetazolamide), antidiabetic drug (insulin), anticonvulsants (phenytoin).

Drug-Food Interaction: Glimicid-M1 Tablet may interact with alcohol. Therefore, avoid the consumption of alcohol with Glimicid-M1 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

Drug-Disease Interaction: If you have severe infections, uncontrolled diabetes, lactic acidosis or ketoacidosis (accumulation of ketone bodies in the blood), dehydration, or liver or kidney problems, inform your doctor before taking Glimicid-M1 Tablet .

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • TRIMETHOPRIM
  • VERAPAMIL
  • CIMETIDINE
  • DOLUTEGRAVIR
  • RANOLAZINE
  • VANDETANIB
  • CRIZOTINIB
  • OLAPARIB
  • FLUCONAZOLE
  • MICONAZOLE
  • ACETAZOLAMIDE
  • INSULIN
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

  • Maintain healthy body weight as obesity is also related to the onset of diabetes.

  • Maintain a low-fat and low-sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.

  • Avoid consumption of alcohol and quit smoking.

Special Advise

Regular blood tests are recommended while taking Glimicid-M1 Tablet to monitor blood sugar levels.

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increased chance of heart attack or stroke.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Glimicid-M1 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Unsafe

Glimicid-M1 Tablet is not recommended for pregnant women as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Glimicid-M1 Tablet as it may be excreted in breastmilk and cause adverse effects in the baby. Therefore, please consult a doctor before using Glimicid-M1 Tablet if you are breastfeeding.

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Driving

Caution

Glimicid-M1 Tablet may decrease alertness in some people. Therefore, drive only if you are alert after taking Glimicid-M1 Tablet .

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Liver

Caution

Take Glimicid-M1 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Glimicid-M1 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Glimicid-M1 Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

940/2, Janjar No 1264/1, Shop No 2 Ground Floor Ashrama Road, Hinkal Mysore Mysore KA 570017 IN
Other Info - GLI1078

Author Details

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FAQs

Glimicid-M1 Tablet is indicated in the treatment of type 2 diabetes mellitus.
Glimicid-M1 Tablet works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.
Glimicid-M1 Tablet may increase the risk of low blood sugar levels especially with alcohol intake, exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Glimicid-M1 Tablet on your own as discontinuing Glimicid-M1 Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimicid-M1 Tablet , please consult your doctor so that alternative medicine may be prescribed.
You are not recommended to take Glimicid-M1 Tablet with phenytoin as it may reduce the effect of Glimicid-M1 Tablet and increase blood sugar levels. However, please consult a doctor before using Glimicid-M1 Tablet with other medicines.
Include a diet rich in fruits, vegetables and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
You are advised to take Glimicid-M1 Tablet for the duration recommended by the doctor.
Store Glimicid-M1 Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Glimicid-M1 Tablet may cause lactic acidosis (builds up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Glimicid-M1 Tablet is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as noninsulin-dependent diabetes mellitus.
Side effects of Glimicid-M1 Tablet are stomach pain, nausea, diarrhoea, vomiting, headache or metallic taste. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Long-term use of Glimicid-M1 Tablet may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.
You are recommended to avoid consumption of alcohol with Glimicid-M1 Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
Glimicid-M1 Tablet should be swallowed as a whole with water; do not crush, break or chew it.
Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimicid-M1 Tablet . Avoid drinking alcohol.
Other medicines should be taken with Glimicid-M1 Tablet only if prescribed by the doctor. To prevent any interactions it is advised to consult the doctor before taking other medicines during treatment with Glimicid-M1 Tablet .

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