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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Glifaz 25mg Tablet is used in the treatment of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It contains Empagliflozin, which lowers kidney reabsorption of glucose and increases urine excretion of glucose. Thus, it lowers blood sugar levels. In some cases, you may experience certain common side effects such as thrush, pain or a burning sensation when you pee, peeing more than normal, and mild skin rash or itchy skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Glifaz 25mg Tablet

Glifaz 25mg Tablet is used in the treatment of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. Type 2 diabetes is a condition where the body does not make enough insulin, or the insulin that it makes does not work properly.

Glifaz 25mg Tablet contains empagliflozin, which works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme in the kidney's proximal tubules. It lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2. As a result, it lowers blood sugar levels in diabetics.

Take Glifaz 25mg Tablet as prescribed. You are advised to take Glifaz 25mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as thrush, pain or a burning feeling when you pee, peeing more than normal, and mild skin rash or itchy skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if you experience these side effects persistently.

Do not consume Glifaz 25mg Tablet if you are allergic to any component present in Glifaz 25mg Tablet. If you are pregnant or breastfeeding, consult your doctor before taking Glifaz 25mg Tablet. Avoid drinking alcohol while taking Glifaz 25mg Tablet since it may produce unpleasant side effects. There is limited information available about the use of Glifaz 25mg Tablet in children. Therefore, it is not recommended for use in children. Inform your doctor about all of the medications you are taking, as well as your medical history, to rule out any undesirable side effects or interactions.

Uses of Glifaz 25mg Tablet

Treatment of Type 2 diabetes mellitus

Medicinal Benefits

Glifaz 25mg Tablet plays a vital role in managing diabetes and achieving good control of blood sugar levels by delaying the absorption of sugar and increasing insulin sensitivity in the body. Glifaz 25mg Tablet does not cause a sudden lowering of the blood glucose level or cause significant hypoglycaemia. In the prediabetic condition, Glifaz 25mg Tablet is the only recommended treatment available. Glifaz 25mg Tablet also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of foot! Glifaz 25mg Tablet also helps to reduce your chance of having a heart attack or stroke.

Directions for Use

Swallow Glifaz 25mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Glifaz 25mg Tablet

  • Thrush (fungal infection)

  • Pain or a burning feeling when you pee

  • Peeing more than normal

  • Mild skin rash or itchy skin

Drug Warnings

If you are allergic to any of the ingredients in Glifaz 25mg Tablet, do not consume it. If you suffer heart abnormalities, diabetic ketoacidosis, skin problems, acute pancreatitis, low blood sugar levels, or kidney or liver problems, notify your doctor. If you are pregnant or breastfeeding, consult your doctor before taking Glifaz 25mg Tablet. Avoid drinking alcohol while taking Glifaz 25mg Tablet since it may produce unpleasant side effects. Inform your doctor about all the medications you are taking and your medical history to rule out any unwanted side effects.

Drug Interactions

Drug-Drug Interactions: Glifaz 25mg Tablet may interact with insulin, high blood pressure-lowering pills (hydrochlorothiazide, amlodipine), water pills/diuretics (furosemide), antibiotics used for eye infections (gatifloxacin), anti-hypertensive (metoprolol), steroids (prednisolone), thyroid hormones etc. So, tell your doctor if you are using these drugs before taking the Glifaz 25mg Tablet.

Drug-Food Interactions: Taking Glifaz 25mg Tablet with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) and hypoglycaemia.

Drug-Disease Interactions: Glifaz 25mg Tablet should be avoided in patients with vitamin B12 deficiency, kidney problems, liver problems, cardiovascular disease (heart-related issues), and low blood sugar level (hypoglycaemia) as it may worsen the condition.

Drug-Drug Interactions Checker List

  • HYDROCHLOROTHIAZIDE
  • AMLODIPINE
  • FUROSEMIDE
  • DIGOXIN
  • METOPROLOL
  • PREDNISOLONE
  • GATIFLOXACIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.

  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.

  • Follow a healthy diet and walk for at least 45minutes to complement treatment with Glifaz 25mg Tablet.

  • Maintain a healthy weight by exercising regularly.

  • Rest properly, and avoid stress by doing meditation or yoga.

Special Advise

  • Keep taking Glifaz 25mg Tablet even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose; consult your treating physician for advice. 

  • Take short, frequent meals, and avoid prolonged fasting when taking Glifaz 25mg Tablet. Beware of symptoms of hypoglycaemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience any of the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially during long travels.

Disease/Condition Glossary

Type 2 diabetes: Type 2 diabetes is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to insulin action. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also include neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increased chance of heart attack or stroke.

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Alcohol

Unsafe

It is advisable not to consume alcohol along with Glifaz 25mg Tablet to avoid unpleasant side effects like lactic acidosis.

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Pregnancy

Caution

Glifaz 25mg Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk. You should not take Glifaz 25mg Tablet without a doctor's advice.

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Breast Feeding

Unsafe

Glifaz 25mg Tablet is not recommended if you are breastfeeding or if you are planning to breastfeed your baby.

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Driving

Safe if prescribed

Glifaz 25mg Tablet should not affect your ability to drive or operate machinery/tools.

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Liver

Caution

Glifaz 25mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Glifaz 25mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal functions. Glifaz 25mg Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Glifaz 25mg Tablet.

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Children

Safe if prescribed

Glifaz 25mg Tablet is not recommended for children below ten years of age. The dose is to be adjusted and recommended by a child specialist only for children over ten years.

Other Info - GLIF918

Author Details

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FAQs

Glifaz 25mg Tablet is used to treat type 2 diabetes when diet and exercise alone cannot control your blood sugar levels.
Glifaz 25mg Tablet contains empagliflozin, which blocks the sodium-glucose co-transporter-2 (SGLT-2) enzyme in the kidney's proximal tubules. It lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2. As a result, it lowers blood sugar levels in diabetics.
Yes, Glifaz 25mg Tablet can cause a minor upset of the stomach. However, do not stop taking it. Discuss with your doctor in case of severe stomach upset.
If you feel thirsty after taking Glifaz 25mg Tablet, it may be because of dehydration as Glifaz 25mg Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.
If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact doctor as it can be a condition of type 2 diabetes.
In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar levels in your body. So, it is advisable to keep sugar candies with you.
Lactic acidosis is a rare but life-threatening condition when there is too much lactic acid build up in the bloodstream. Long term intake of Glifaz 25mg Tablet may lead to lactic acidosis when cells get deprived of oxygen levels. Symptoms of lactic acidosis include the burning sensation of the muscle, muscle ache, fast breathing, nausea, and stomach pain. Immediately contact the doctor about this complication.
Glifaz 25mg Tablet should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease or liver disease. It is also not advised to use this drug if you drink too much alcohol. Make sure to inform your health care professional if you are pregnant or breastfeeding.
If you have been affected by diabetes, you should have a test of HbA1c once in three months.
No. Till date there is no clinical evidence that states that Glifaz 25mg Tablet affects fertility in either men or women.
Hypoglycaemia refers to low blood sugar levels. The symptoms of hypoglycaemia include nausea, headache, irritability, hunger, sweating, dizziness.
No. Glifaz 25mg Tablet is only prescribed for treating type 2 diabetes, also called 'non-insulin-dependent diabetes.
Glifaz 25mg Tablet should be swallowed as a whole with water. Do not crush or chew it.
Glifaz 25mg Tablet should not be discontinued without a doctor's consultation. Stopping Glifaz 25mg Tablet might increase blood sugar levels.
Glifaz 25mg Tablet can be used with other diabetes medicines if prescribed by the doctor.
Taking Glifaz 25mg Tablet with other anti-diabetic medicines may cause hypoglycaemia. Symptoms include headache, excessive hunger, sweating, shaking, confusion, and fast heart rate. Carry glucose biscuits or candy and consume them if you experience these symptoms.
A haemoglobin A1C (HbA1C) test is used to diagnose type 2 diabetes and prediabetes. It helps measure the amount of blood glucose attached to haemoglobin. It is used to monitor your condition and check how well you've been able to control your blood sugar levels.
Glifaz 25mg Tablet may add to the diuretic effects of furosemide, increasing the risk of dehydration, kidney problems, and low blood pressure. This may cause headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Before starting Glifaz 25mg Tablet, consult the doctor if you are taking furosemide.
Side effects of Glifaz 25mg Tablet include thrush (genital yeast infection), passing more urine than usual, itching, rash or red skin, thirst, and constipation.

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