Glafen MR 100mg/325mg Tablet is used to reduce pain and inflammation. The pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Inflammation is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful, especially as a reaction to injury or infection.

Glafen MR 100mg/325mg Tablet is composed of two medicines: Aceclofenac (pain reducer) and Paracetamol (fever reducer). Glafen MR 100mg/325mg Tablet helps in relieving pain from conditions like headaches, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Aceclofenac and Paracetamol both work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Glafen MR 100mg/325mg Tablet may cause side effects like dizziness, nausea (feeling sick), digestion problems (constipation, flatulence, diarrhoea) and skin reactions (like rashes and hives). Most of the side effects of Glafen MR 100mg/325mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Taking more than the daily prescribed dose of Glafen MR 100mg/325mg Tablet may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash, itching, gastrointestinal bleeding and/or ulcer. Use this medicine in the prescribed doses and seek immediate medical help if you experience such symptoms.

Glafen MR 100mg/325mg Tablet helps to reduce pain and inflammation caused by various complications or conditions. It significantly works on providing relief from pain for extended hours. It contains paracetamol, which is less irritant to the stomach than other painkillers. Hence, it is well tolerated by patients who have an allergy to aspirin or a risk of gastrointestinal bleeding or ulcer formation. Besides this, it does not affect bleeding time and also helps in reducing fever due to pain or swelling.

• Dizziness
• Nausea
• Digestion problems (like constipation, flatulence, diarrhoea)
• Increased liver enzymes in the blood (diagnosed through liver function test)

Taking more than the daily prescribed dose of Glafen MR 100mg/325mg Tablet may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash or itching. Most of the cases of liver injury are associated with the use of paracetamol. Gastrointestinal bleeding and ulcer formation are commonly observed with the use of Glafen MR 100mg/325mg Tablet, so the doctor may prescribe you the lowest dose available. Do not take Glafen MR 100mg/325mg Tablet if you have asthma or allergies to painkillers, heart, kidney and liver conditions. Glafen MR 100mg/325mg Tablet should not be taken during pregnancy or by breastfeeding mothers as it may affect the baby.

Drug-Drug Interaction: Glafen MR 100mg/325mg Tablet interact with cholesterol lowering drugs (cholestyramine), charcoal, medicine to stop vomiting (domperidone, metochlopramide), alcohol, anti HIV drug (zidovudine), blood thinner (warfarin), blood pressure lowering medicine, anti cancer or anti arthritis drug (methotrexate) may lead to drug toxicity or affect the working of Glafen MR 100mg/325mg Tablet. So, contact the doctor before taking these medicines.

Drug-Food Interaction: No interaction found.

Drug-Disease Interaction: Patient affected with liver disease, bleeding disorder and alcoholism should not take Glafen MR 100mg/325mg Tablet as it has a risk of causing derangement in liver functions.

• CHOLESTYRAMINE
• CHARCOAL
• DOMPERIDONE
• METOCLOPRAMIDE
• ZIDOVUDINE
• ALCOHOL
• WARFARIN
• METHOTREXATE

• Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
• Do not go for heavy exercise as it may increase your joint pain and arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
• In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• The components of Glafen MR 100mg/325mg Tablet have the tendency to cause stomach upset. Thus, it is recommended to consume Glafen MR 100mg/325mg Tablet with meals to minimize gastric side effects. If you have a diagnosis of peptic ulcer, Glafen MR 100mg/325mg Tablet is best avoided unless prescribed by your doctor.
• Paracetamol is a component of Glafen MR 100mg/325mg Tablet which can cause liver injury when in taken in large doses. Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
• Although it is generally a safe medicine to use, it should be avoided in patients with kidney disease as Glafen MR 100mg/325mg Tablet may have an adverse effect on renal functions.
• Use with caution in pregnancy and breastfeeding. Do not self-administer Glafen MR 100mg/325mg Tablet if you are pregnant or are nursing.
• Although Glafen MR 100mg/325mg Tablet provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve the best results, it is strongly recommended to remain physically active as much as your condition allows. Adopting a healthy lifestyle, coupled with a healthy diet containing high proteins, is the mainstay of the management of arthritic conditions.

Pain: It is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. When you do something that hurts your body, your brain triggers the pain response.

Inflammation: It is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful, especially as a reaction to injury or infection.