Giclametose 80/0.3 Tablet is indicated in treating type 2 diabetes mellitus. Type 2 diabetes is a chronic or lifelong condition affecting how your body processes glucose. People with type 2 diabetes either do not produce enough insulin, or if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). Due to this, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. It can lead to serious complications like skin infection, eye problems (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure and even stroke.

Giclametose 80/0.3 Tablet combines three antidiabetic drugs: Voglibose, Metformin, and Gliclazide. Voglibose is an alpha-glucosidase inhibitor that prevents the breakdown of complex sugars into simple sugars such as glucose. In this way, it prevents the sudden rise in sugar levels after every meal. Gliclazide is a 'sulfonylurea' that acts by increasing the insulin released by the pancreas. On the other hand, Metformin, which is a 'biguanide', acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's response to insulin. In a nutshell, the three medicines together prevent blood glucose levels from rising to very high levels, thus keeping your Diabetes under control. Giclametose 80/0.3 Tablet act together to keep your blood sugar levels under check. The strict control of blood sugars is especially important to mention the many disabling side effects of Diabetes. Giclametose 80/0.3 Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc. 

Giclametose 80/0.3 Tablet should be taken with food to avoid an upset stomach. Giclametose 80/0.3 Tablet should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. A common side effect of Giclametose 80/0.3 Tablet is hypoglycemia (low blood glucose levels), characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. So, to avoid hypoglycemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

You should not take Giclametose 80/0.3 Tablet if you have diabetic ketoacidosis (excess acids in your blood). Giclametose 80/0.3 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Giclametose 80/0.3 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Giclametose 80/0.3 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease, are or are planning to get pregnant, or are breastfeeding.

Giclametose 80/0.3 Tablet is a combination of three anti-diabetic drugs: Voglibose, Metformin, and Gliclazide. Voglibose is an alpha-glucosidase inhibitor that prevents the breakdown of complex sugars into simple sugars such as glucose. In this way, it prevents the sudden rise in sugar levels after every meal. Gliclazide is a 'sulfonylurea' that acts by increasing the insulin released by the pancreas. On the other hand, Metformin, which is a 'biguanide', works by lowering the glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's response to insulin. In a nutshell, the three medicines prevent blood glucose levels from rising to very high levels, thus keeping your Diabetes under control. Giclametose 80/0.3 Tablet act together to keep your blood sugar levels under check. The strict control of blood sugars is especially important to mention the many disabling side effects of Diabetes. Giclametose 80/0.3 Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.

• Hypoglycemia (low blood glucose level)

• Dizziness

• Sweating

• Palpitations

• Hunger pangs

• Dry mouth and skin

Some diabetic patients taking Giclametose 80/0.3 Tablet may develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid is accumulated in the blood. So, your liver and kidney's proper functioning is required to eliminate excess lactic acid from the blood. You should not take Giclametose 80/0.3 Tablet if you have kidney disease, as measured by a blood test. Giclametose 80/0.3 Tablet may lower vitamin B12 levels, so try to have blood tests for annual blood and vitamin. Giclametose 80/0.3 Tablet , when used with or without insulin, tends to lower the blood sugar level extremely. So, the doctor may reduce the dose of insulin. Giclametose 80/0.3 Tablet may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.

Drug-Drug Interactions: Giclametose 80/0.3 Tablet may interact with insulin, high blood pressure-lowering pills (hydrochlorothiazide, amlodipine), water pills/diuretics (furosemide), heart failure-related medicines (digoxin), anti-hypertensive (metoprolol), steroids (prednisolone), thyroid hormones, etc. So, tell your doctor if you are using these drugs before taking Giclametose 80/0.3 Tablet .

Drug-Food Interactions: Taking Giclametose 80/0.3 Tablet with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) and hypoglycemia.

Drug-Disease Interactions: Giclametose 80/0.3 Tablet should be avoided in patients with vitamin B12 deficiency, kidney problems, liver problems, cardiovascular disease (heart-related issues), and low blood sugar level (hypoglycemia) as it may worsen the condition.

• ASPIRIN
• GLIPIZIDE
• LEVOTHYROXINE SODIUM
• INSULIN GLARGINE
• SITAGLIPTIN
• METOPROLOL
• FUROSEMIDE

• Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.

• Eat at regular intervals. Do not take the long gap between a meal or snack.

• Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.

• Invest in at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise weekly.

• Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).

• Replace refined carbohydrate-containing foods with whole grain foods and increase intake of fruits, veggies, and other fibre-enriched foods.

• Reduce saturated fat (or hidden fats) intake in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.

• Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress related to blood sugar changes.

• Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).

• Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.

• Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose. Consult your treating physician for advice. 

• Take short, frequent meals, and avoid prolonged fasting when taking this drug. Beware of hypoglycemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 

• Before the doctor prescribes this medicine, it is always better that your physician knows about any underlying conditions like kidney or liver disease, prior heart attack, alcohol intake, etc.

• Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (a decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).

• Try to quit smoking and reduce your intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar etc.

• Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

Diabetes Mellitus type 2 is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, excessive insulin is produced, but it fails to act on the body's organs. Symptoms of type 2 diabetes include feeling exhausted all time, feeling thirsty, having blurry vision, and having the urge to urinate (pee) more often. Complications of type 2 diabetes include skin infection, eye problems (retinopathy), nerve damage (neuropathy), delayed wound healing, diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke. Both low and high blood sugar levels can be dangerous and should be treated as soon as possible. Your H1bA1C below 5.7% is normal, 5.7-6.4% confirms the prediabetes stage, and 6.5% or greater states a diabetes condition.