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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Genxtor Injection is used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours, thus helping treat kidney cancer. Sometimes, Genxtor Injection may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite.

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Manufacturer/Marketer :

Biocon Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Genxtor Injection

Genxtor Injection belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes).

Genxtor Injection contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours. Thereby, it helps treat kidney cancer.

In some cases, Genxtor Injection may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of these side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. Genxtor Injection is not recommended for children below 18 years as the effectiveness has not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Genxtor Injection

Treatment of Renal cell cancer (Kidney cancer)

Medicinal Benefits

Genxtor Injection belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes). Genxtor Injection contains Temsirolimus, a selective inhibitor of the enzyme mTOR (mammalian target of rapamycin) that blocks tumour cell growth and division. Thereby, it helps treat kidney cancer.

Side Effects of Genxtor Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Fever
  • Loss of appetite
  • Sores or inflammation in the mouth
  • Cough

Directions for Use

Genxtor Injection will be administered by a healthcare professional who is trained and experienced in the administration of anticancer medicine; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Genxtor Injection if you are allergic to any of its components if you are allergic to sirolimus (immunosuppressant), or if you have mantle cell lymphoma or liver problems. Inform the doctor if you are allergic to or cannot use anti-histamines if you have/had a tumour in the brain or spinal cord, bruising/bleeding problems, infections, inflammation of lungs, liver or kidney problems, high cholesterol levels, diabetes, eye problems, if you are taking anticoagulants if you drink alcohol or are alcoholic if you are due to undergo any vaccination or surgery, or if you are over 65 years of age. Consult the doctor if you are pregnant or breastfeeding. Genxtor Injection is not recommended for children below 18 years as the effectiveness has not been established.

Therapeutic Class

CHEMOTHERAPY

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, whole grains and fruits in your diet.
  • Avoid fast, fried foods, processed meats, highly processed foods and beverages, and salty snacks.
  • Get optimal sleep; rest well.

Habit Forming

No

How Genxtor Injection Works

Genxtor Injection contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours. Thereby, it helps treat kidney cancer.

What if I have taken an overdose of Genxtor Injection

As Genxtor Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Genxtor Injection may cause cough, difficulty thinking clearly, fever, seizure, hallucinating (seeing things or hearing voices that do not exist), shortness of breath, new or worsening abdominal pain, panting or fast breathing, red blood in stools, diarrhea, leg pain, swelling, tenderness, redness, and understanding reality, or using good judgment.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Genxtor Injection. Please consult the doctor.

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Pregnancy

Caution

Genxtor Injection may cause fetal harm when administered to pregnant women. Genxtor Injection should not be used during pregnancy unless clearly necessary. Consult the doctor if you are pregnant, planning for pregnancy, or thinking you may be pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while using Genxtor Injection and for three weeks after the last dose.

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Driving

Safe

Genxtor Injection is unlikely to affect your ability to drive.

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Liver

Caution

Genxtor Injection is not recommended in patients with liver problems. Consult the doctor if you have/had liver problems.

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Kidney

Caution

Please consult the doctor if you have kidney impairment or any concerns regarding this. Your doctor may monitor kidney function while on treatment with this medicine.

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Children

Unsafe

Genxtor Injection is not recommended for children below 18 years as effectiveness has not been established.

Country of origin

India
Other Info - GE97060

Author Details

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FAQs

Genxtor Injection is used to treat Renal cell cancer (Kidney cancer).
Genxtor Injection works by blocking tumour cell growth and division. Thereby, it helps treat kidney cancer.
Genxtor Injection may result in immunosuppression, leading to an increased risk of infections. Wash your hands frequently and avoid contact with sick people.
Vaccination may be less effective if taken during treatment with Genxtor Injection. Also, some vaccinations should be avoided during treatment. Therefore, do not have any vaccinations without consulting the doctor.
Fertility may be compromised during treatment with Genxtor Injection. Consult the doctor if you have any concerns.

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