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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:53 PM IST
Gentrax 500 Injection 5 ml is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). It contains Ceftriaxone, which kills the bacteria and helps in treating bacterial infection. In some cases, it may cause side effects such as diarrhoea, rashes, changes in results of blood and liver tests, and abnormalities (increase/decrease) in the number of white blood cells and platelets. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Gentrax 500 Injection 5 ml

Gentrax 500 Injection 5 ml is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.

Gentrax 500 Injection 5 ml contains 'Ceftriaxone', which works by interfering with the formation of bacterial cell walls, thereby killing the bacteria. Thus, Gentrax 500 Injection 5 ml helps in treating bacterial infection.

In some cases, Gentrax 500 Injection 5 ml may cause side effects such as diarrhoea, rashes, changes in results of blood and liver tests, and abnormalities (increase/decrease) in the number of white blood cells and platelets. Although not everybody experiences these side effects, if they occur, consult your doctor.

Talk to your doctor before taking Gentrax 500 Injection 5 ml if you have/had received calcium-containing products recently, had diarrhoea after taking antibiotics, inflammation of the bowel, kidney stones, or any other illness. Do not take antacids along with Gentrax 500 Injection 5 ml; maintain a gap of 2-3 hours between both. Consult your doctor if you are pregnant or breastfeeding. Gentrax 500 Injection 5 ml may cause dizziness, so be cautious while driving. Avoid alcohol consumption to prevent unpleasant side effects.

Uses of Gentrax 500 Injection 5 ml

Treatment of Bacterial infections

Medicinal Benefits

Gentrax 500 Injection 5 ml belongs to the group of antibiotic medicines called cephalosporins used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). Gentrax 500 Injection 5 ml is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria. Gentrax 500 Injection 5 ml works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

Directions for Use

Gentrax 500 Injection 5 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gentrax 500 Injection 5 ml

  • Diarrhoea
  • Rashes
  • Changes in results of blood and liver tests
  • Abnormalities (increase/decrease) in the number of white blood cells and platelets

Drug Warnings

Before starting Gentrax 500 Injection 5 ml, please inform your doctor if you are allergic to any of the components in Gentrax 500 Injection 5 ml or against any antibiotic. Talk to your doctor if you have/had received calcium-containing products recently, had diarrhoea after taking antibiotics, inflammation of the bowel, kidney stones, or any other illness. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Gentrax 500 Injection 5 ml to prevent unpleasant side effects. Gentrax 500 Injection 5 ml may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug Interactions

Drug-Drug Interactions: Gentrax 500 Injection 5 ml may interact with a diuretic (furosemide) and antibiotic (chloramphenicol).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), hyperbilirubinemia (excess bilirubin in the blood), gall bladder disease, pancreatitis, seizures, kidney or liver disease.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Special Advise

  • Gentrax 500 Injection 5 ml might affect the result of diagnostic tests like Coombs’ test (a test for some blood problems), galactosaemia (an abnormal build-up of the sugar galactose), and glucose tests. So tell your doctor that you are taking Gentrax 500 Injection 5 ml before undergoing these tests.

  • Gentrax 500 Injection 5 ml must not be mixed or administered simultaneously with calcium-containing solutions, including total parenteral nutrition.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause illness. They can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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Alcohol

Caution

Avoid consuming alcohol while taking Gentrax 500 Injection 5 ml to prevent unpleasant side-effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Gentrax 500 Injection 5 ml only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will prescribe Gentrax 500 Injection 5 ml only if the benefits outweigh the risks.

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Driving

Caution

Gentrax 500 Injection 5 ml may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

Gentrax 500 Injection 5 ml is safe for children if prescribed by a doctor. Gentrax 500 Injection 5 ml is not recommended for a premature baby, or a newborn baby who has jaundice (yellowing of the skin or eyes).

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - GEN0614

Author Details

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FAQs

Gentrax 500 Injection 5 ml is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).
Gentrax 500 Injection 5 ml works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.
Gentrax 500 Injection 5 ml may cause dizziness, so drive only if you are alert and omit driving and operating machinery if you experience dizziness.
Diarrhoea might be a side-effect of Gentrax 500 Injection 5 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Gentrax 500 Injection 5 ml may affect the results of urine tests for sugar and blood test known as coomb’s test (antiglobulin test). Inform the person performing the tests that you are taking Gentrax 500 Injection 5 ml.
Do not take antacids along with Gentrax 500 Injection 5 ml; maintain a gap of 2-3 hours between both. However, consult your doctor before taking other medicines while on treatment with Gentrax 500 Injection 5 ml.
Yes, Gentrax 500 Injection 5 ml is generally considered safe when taken in the recommended dose and duration as directed by your doctor. However, sometimes it may cause side effects or allergic reactions in some individuals. Please let your doctor know if any of the side effects bother you.
Gentrax 500 Injection 5 ml usually starts working within a few hours after administration. However, Gentrax 500 Injection 5 ml may take a few days to show its full effect, depending on the infection being treated. If your symptoms do not improve or get worse, please consult your doctor.
Gentrax 500 Injection 5 ml should not be used by individuals who are allergic to its components or other cephalosporin antibiotics. It is also not recommended for use in newborns, especially those with jaundice (yellowing of the skin or eyes).
If you do not feel better after using Gentrax 500 Injection 5 ml, it could mean that the infection isn't responding to the antibiotic, or you might have a different type of infection that needs a different treatment. Please consult your doctor for further evaluation and to discuss possible changes to your treatment plan.
Gentrax 500 Injection 5 ml is usually eliminated from the body within 5 to 9 hours in healthy individuals. However, Gentrax 500 Injection 5 ml may stay in the body for longer depending on the individual's medical condition.
Yes, Gentrax 500 Injection 5 ml is effective against a wide range of bacterial infections, including respiratory, urinary tract, skin, and bloodstream infections.
Gentrax 500 Injection 5 ml will be administered either intravenously (IV) or intramuscularly (IM), depending on the condition being treated, by your healthcare provider. Please do not self-administer.
No, you should complete the full course of treatment with Gentrax 500 Injection 5 ml as prescribed by your doctor, even if you feel better. Please consult your doctor before stopping the medication early, as your infection may not be completely treated and the bacteria may become resistant to the antibiotics.
If you are allergic to Cefuroxime, there is a possible risk of an allergic reaction to Gentrax 500 Injection 5 ml, since both are in the same group of antibiotics (cephalosporins). Please consult your healthcare provider before taking Gentrax 500 Injection 5 ml or any other cephalosporin antibiotics to ensure safety.
Before starting Gentrax 500 Injection 5 ml, you should inform your doctor if you have recently received calcium-containing products, have had diarrhoea after taking antibiotics, or have a history of colitis (inflammation of the large intestine), malnutrition (inability to consume or digest essential nutrients), problems with vitamin K levels, or kidney or liver disease.
No, Gentrax 500 Injection 5 ml should only be administered by a healthcare professional, as it requires proper injection technique and monitoring for potential side effects. Please do not administer Gentrax 500 Injection 5 ml at home.

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