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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:37 PM IST

Genstron 500 Injection 2 ml is used to prevent premature labour. It contains Hydroxyprogesterone, which modulates the immune response of pregnant women to prevent rejection of the embryo and allow its attachment to the uterus. It prevents miscarriage and helps lower the risk of premature birth in pregnant women who have had past premature labour. In some cases, you may experience certain common side effects such as nausea, vomiting, itching, hives (skin rashes), swelling in the face, lips, tongue, or throat, and diarrhoea.

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Genstron 500 Injection 2 ml

Genstron 500 Injection 2 ml belongs to the category of a synthetic progesterone female hormone called progestin used to prevent premature labour. Premature labour can start before 37 completed weeks of pregnancy and can be caused by premature rupture of membranes, high blood pressure during pregnancy (pre-eclampsia), and poor diet. Preterm labour symptoms include leaking fluid or bleeding from the vagina, the feeling of pressure in the pelvis, and cramps that feel like menstrual cramps regularly.

Genstron 500 Injection 2 ml contains 'Hydroxyprogesterone', a progestin (female hormones) that modulates the immune response of pregnant women to prevent rejection of the embryo and allow its attachment to the uterus. Genstron 500 Injection 2 ml prevents miscarriage and helps lower the risk of premature birth in pregnant women who have had past premature labour. Genstron 500 Injection 2 ml should be administered only to those pregnant women who are pregnant with one baby or who have had a preterm (premature) delivery of one baby in the past.

Genstron 500 Injection 2 ml will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side effects such as nausea, vomiting, itching, hives (skin rashes), swelling in the face, lips, tongue, or throat, and diarrhoea. Not everybody experiences these side effects. Most of the side effects of Genstron 500 Injection 2 ml do not require medical attention and gradually resolve over time. Talk to your doctor if you feel any discomfort while taking Genstron 500 Injection 2 ml.

Before starting Genstron 500 Injection 2 ml, please inform your doctor if you have an allergy to any medicines, have unusual vaginal bleeding related to your pregnancy, liver disease, severe hypertension (high blood pressure), or a history of breast cancer, uterus or vagina. Tell your doctor before using Genstron 500 Injection 2 ml if you have had pre-eclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, or epilepsy. Genstron 500 Injection 2 ml may cause dizziness, so be cautious while driving and operating machinery. Avoid alcohol consumption to prevent unpleasant side effects. Inform your doctor about all medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of Genstron 500 Injection 2 ml

Treatment of Premature labor.

Medicinal Benefits

Genstron 500 Injection 2 ml contains “Hydroxyprogesterone” a progestin (female hormones) that is used in pregnant women who have delivered a baby too early (preterm) in the past. It works by modulating the immune response of pregnant women to prevent the rejection of the embryo and allow its attachment to the uterus. Genstron 500 Injection 2 ml prevents miscarriage and helps lower the risk of premature birth in pregnant women who have had a past premature delivery.

Directions for Use

A healthcare professional will administer Genstron 500 Injection 2 ml. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Genstron 500 Injection 2 ml

  • Nausea
  • Vomiting
  • Itching
  • Hives (skin rashes)
  • Swelling in the face, lips, tongue, or throat
  • Diarrhea

Drug Warnings

You should not take Genstron 500 Injection 2 ml without a doctor's advice. Before starting Genstron 500 Injection 2 ml, please inform your doctor if you have an allergy to any medicines. Do not take Genstron 500 Injection 2 ml if you have unusual vaginal bleeding that is not related to your pregnancy, liver disease, severe hypertension (high blood pressure), or history of cancer of the breast, uterus or vagina. Tell your doctor before using Genstron 500 Injection 2 ml if you have had preeclampsia (high blood pressure during pregnancy), thromboembolic disorders (blood clot form in the blood), diabetes, depression, or epilepsy. Do not take Genstron 500 Injection 2 ml on your own. Genstron 500 Injection 2 ml can cause dizziness and drowsiness. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. Let your doctor know if you are a breastfeeding mother. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Genstron 500 Injection 2 ml is not recommended for children younger than 16 years old. Genstron 500 Injection 2 ml is not intended for use in the first trimester of pregnancy.

Drug Interactions

Drug-Drug interaction: This Genstron 500 Injection 2 ml interacts with pain killers (acetaminophen) anti-epilepsy medicines (primidone, phenytoin, carbamazepine), antidiabetics (metformin, glimepiride, glipizide, canagliflozin), medicines used to treat HIV (efavirenz) medicine used to treat fungal infections (griseofulvin, ketoconazole, itraconazole, posaconazole).

Drug-Food Interaction: Genstron 500 Injection 2 ml may interact with grapefruit and alcohol. 

Drug-Disease Interaction: Genstron 500 Injection 2 ml should be taken with caution in breast cancer, thromboembolism (blood clot form in blood vessels), depression, diabetes, fluid retention (excess fluid builds up within the body), and kidney or liver disease.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • PRIMIDONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • METFORMIN
  • GLIMEPIRIDE
  • GLIPIZIDE
  • CANAGLIFLOZIN
  • EFAVIRENZ
  • GRISEOFULVIN
  • KETOCONAZOLE
  • POSACONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet rich in vegetables, fruits, and whole grains to reduce the risk of preterm delivery.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil.
  • I prefer whole foods and grains to processed ones. I avoid processed foods and foods high in sugar and fat.
  • Avoid stress, as it can increase the chances of preterm delivery. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Regular physical activity and yoga keep you fit, help improve blood circulation, and regulate the oxygen supply, thereby improving your chances of carrying your baby full term.
  • Quitting smoking is the best strategy to lower the risk of premature delivery.
  • Keep your weight under control.
  • Try to avoid alcohol as it can affect your stomach and intestine and limit the absorption of the important nutrients required by your body.

Special Advise

  • You should not be treated with Genstron 500 Injection 2 ml if you are allergic to hydroxyprogesterone or castor oil.
  • Genstron 500 Injection 2 ml is not recommended for use in women less than 16 years of age.
  • Genstron 500 Injection 2 ml will not stop premature labour in the women in whom it has already begun.
  • Genstron 500 Injection 2 ml is for women pregnant with only 1 child and not for use in women who are pregnant with more than one baby (twins, triplets, etc).

Disease/Condition Glossary

Preterm labour: Preterm labour, also called premature labour, is when your baby starts getting ready for birth too early in your pregnancy. It can start before 37 completed weeks of pregnancy. Premature labour can be caused by premature rupture of membranes, high blood pressure during pregnancy (pre-eclampsia), and poor diet. Symptoms of preterm labour include leaking fluid or bleeding from the vagina, the feeling of pressure in the pelvis, and cramps that feel like menstrual cramps regularly. Few premature babies need special care and also have long-term mental and physical disabilities.

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Alcohol

Caution

There is not enough scientific data available for Genstron 500 Injection 2 ml interaction with alcohol, hence it is best to consult a doctor.

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Pregnancy

Safe if prescribed

Safe if prescribed.

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Breast Feeding

Caution

Please consult your doctor before using Genstron 500 Injection 2 ml during breastfeeding.

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Driving

Caution

It is advised to drive with caution after taking Genstron 500 Injection 2 ml as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

Genstron 500 Injection 2 ml should be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose.

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Kidney

Caution

Genstron 500 Injection 2 ml should be taken with caution, especially if you have a history of kidney liver diseases/conditions. Your doctor may have to adjust the dose.

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Children

Unsafe

Genstron 500 Injection 2 ml not indicated for use in children. Safety and effectiveness in pediatric patients less than 16 years of age have not been established.

Country of origin

India

Manufacturer/Marketer address

Jyotsna Vihar, 1162/2268, Near Sky Automobiles, Bhanpur, Cuttack-753011, Odisha, India
Other Info - GEN0531

Author Details

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FAQs

Genstron 500 Injection 2 ml is used to prevent premature labour. It prevents miscarriage and helps lower the risk of premature birth in pregnant women.
Genstron 500 Injection 2 ml may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Genstron 500 Injection 2 ml, please consult your doctor.
Genstron 500 Injection 2 ml works by modulating the immune response of pregnant women to prevent the rejection of the embryo and allow its attachment to the uterus.
Genstron 500 Injection 2 ml should be taken in the dose and duration as prescribed by the doctor.
Progesterone is an endogenous steroid and progestogen sex hormone secreted by the female reproductive part in the second half of the menstrual cycle to prepare for the release of the egg in the uterus. It is also necessary for the implantation of the fertilized egg in the uterus, for maintaining pregnancy and in hormonal replacement therapy in women deficient in progesterone.
Some of the common side effects of Genstron 500 Injection 2 ml include nausea, vomiting, itching, hives (skin rashes), swelling of the face, lips, tongue, or throat, and diarrhoea.
You should stop using Genstron 500 Injection 2 ml and tell a doctor before using Genstron 500 Injection 2 ml if you have uncontrolled high blood pressure (hypertension), unusual vaginal bleeding, liver disease, liver cancer, jaundice during pregnancy, circulation problems or bleeding problems, stroke, blood clot problems, breast cancer, uterus/cervix/vaginal cancer.
Since Genstron 500 Injection 2 ml is administered by a doctor, it's unlikely you will stop taking Genstron 500 Injection 2 ml on your own. Complete the duration of treatment as prescribed by the doctor.
Genstron 500 Injection 2 ml prevents miscarriage and helps lower the risk of premature birth in pregnant women who have had past premature labour.
You should stop using Genstron 500 Injection 2 ml if you have uncontrolled high blood pressure (hypertension), unusual vaginal bleeding, liver disease, liver cancer, jaundice during pregnancy, circulation problems or bleeding problems, stroke, blood clot problems, breast cancer, uterus/cervix/vaginal cancer.
Genstron 500 Injection 2 ml is a synthetic progesterone female hormone called progestin used to prevent premature labour.
Genstron 500 Injection 2 ml will be administered by a doctor. The doctor will determine the dose based on your condition.
Since Genstron 500 Injection 2 ml is administered by a doctor, it's unlikely for you to miss a dose. Consult the doctor if you think you have missed a dose.
You should not receive Genstron 500 Injection 2 ml if you are allergic to any of its components, if you have blood clotting problems, uncontrolled high blood pressure, or breast cancer.

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