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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Genfour-LP Eye Drops 5 ml is used to treat bacterial eye infections or eye discomfort. It is also used in patients who have undergone eye surgeries. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. It contains Moxifloxacin and Loteprednol, which kills bacteria and blocks the production of prostaglandins (chemical messengers making the eye red, swollen, and itchy). Thus, it prevents the spread of eye infections caused by bacteria and reduces inflammation and pain. It may cause common side effects such as redness in the eyes, blurred vision, burning or stinging sensation in the eye, and eye discomfort. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

OPHTHALMIC

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Genfour-LP Eye Drops 5 ml

Genfour-LP Eye Drops 5 ml belongs to a group of medications called 'Antibiotics and Corticosteroids' used to treat bacterial eye infections or eye discomfort. It is also used in patients who have undergone eye surgeries. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). Genfour-LP Eye Drops 5 ml is used to prevent or treat only bacterial eye infections. It does not work against infections caused by viruses and fungi.

Genfour-LP Eye Drops 5 ml contains two medicines: Moxifloxacin (antibiotic) and Loteprednol (corticosteroid). Moxifloxacin belongs to a class of drugs called fluoroquinolone antibiotics. Moxifloxacin is an antibiotic that helps treat and prevent a wide range of bacterial infections. It kills bacteria (bactericidal action) by preventing the synthesis of enzymes, namely DNA gyrase and Topoisomerase II and IV, which is essential for the growth and survival of the bacterial cell. Loteprednol belongs to the class of corticosteroids. It blocks prostaglandins' production (chemical messengers), making the eye red, swollen, and itchy. Together, Genfour-LP Eye Drops 5 ml prevents the spread of eye infections caused by bacteria and reduces inflammation and pain.

Genfour-LP Eye Drops 5 ml is available in the form of an ophthalmic solution (eye drops). Your doctor will advise on how often you take Genfour-LP Eye Drops 5 ml based on your medical condition. Some common side effects of eye drop formulation of Genfour-LP Eye Drops 5 ml include redness in the eyes, blurred vision, burning or stinging sensation in the eye, and eye discomfort. These side effects do not require medical attention and gradually resolve over time.

Please do not use Genfour-LP Eye Drops 5 ml without consulting your doctor if you have a damaged cornea, ulcers in the eye, eye infection and producing pus, open lesions in the eye, and glaucoma (a condition where the pressure inside the eye is increased). Inform your doctor if you are pregnant or breastfeeding before using Genfour-LP Eye Drops 5 ml. Avoid touching the eyedropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. If you wear contact lenses, please inform your doctor since the Genfour-LP Eye Drops 5 ml may contain additives like Benzalkonium chloride that change the lens's colour. Genfour-LP Eye Drops 5 ml sometimes may make your eye red after administration; in such cases, please avoid wearing a lens until the eye improves. Avoid driving or operating machines since the administration of eye drops of Genfour-LP Eye Drops 5 ml cause blurred vision for a while after use.

Uses of Genfour-LP Eye Drops 5 ml

Treatment of Bacterial eye infections, allergic eye conditions.

Directions for Use

Genfour-LP Eye Drops 5 ml is for ophthalmic use only. Wash your hands thoroughly before and after using Genfour-LP Eye Drops 5 ml. Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Replace the outer cap after use. Please do not touch the container’s tip to the eye, eyelids or surrounding areas as it may contaminate Genfour-LP Eye Drops 5 ml.

Medicinal Benefits

Genfour-LP Eye Drops 5 ml is a combination of two medicines: Moxifloxacin and Loteprednol. Moxifloxacin is a fluoroquinolone and broad-spectrum antibiotic. It can act against both gram-positive and gram-negative bacteria. It kills bacteria (bactericidal action) by preventing the synthesis of enzymes, namely DNA gyrase and Topoisomerase II and IV, which is essential for the growth and survival of the bacterial cell. Loteprednol is a corticosteroid with anti-inflammatory properties and acts by inhibiting the chemicals such as prostaglandins production (chemical messengers) that make the eye red, swollen, and itchy. It reduces symptoms associated with infection, such as redness and irritation of the eye, and decreases the risk of infections. Collectively, Genfour-LP Eye Drops 5 ml treats and prevents bacterial eye infections and eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. Genfour-LP Eye Drops 5 ml is used to prevent or treat only bacterial eye infections. It does not work against infections caused by viruses and fungi.

How Genfour-LP Eye Drops 5 ml Works

Genfour-LP Eye Drops 5 ml contains two medicines: Moxifloxacin (antibiotic) and Loteprednol (corticosteroid). Moxifloxacin belongs to a class of drugs called fluoroquinolone antibiotics. Moxifloxacin is an antibiotic that helps treat and prevent a wide range of bacterial infections. It kills bacteria (bactericidal action) by preventing the synthesis of enzymes, namely DNA gyrase and Topoisomerase II and IV, which is essential for the growth and survival of the bacterial cell. Loteprednol belongs to the class of corticosteroids. It blocks prostaglandins' production (chemical messengers), making the eye red, swollen, and itchy. Together, Genfour-LP Eye Drops 5 ml prevents the spread of eye infections caused by bacteria and reduces inflammation and pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Genfour-LP Eye Drops 5 ml

  • Blurred vision
  • Burning/stinging sensation in the eyes
  • Redness in the eyes
  • Watery eyes
  • Inflammation of cornea

What if I have taken an overdose of Genfour-LP Eye Drops 5 ml

Do not use Genfour-LP Eye Drops 5 ml in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you are allergic to Genfour-LP Eye Drops 5 ml or any other medicines. Before taking Genfour-LP Eye Drops 5 ml, inform your doctor if you have vision problems, severe eye pain, ulcers, glaucoma (raised pressure in the eye), eye injury, or have undergone eye surgery or any other eye drops or eye ointment. If you wear contact lenses, please inform your doctor since Genfour-LP Eye Drops 5 ml may contain additives like Benzalkonium chloride that change the lens's colour. Genfour-LP Eye Drops 5 ml sometimes may make your eye red after administration; in such cases, please avoid wearing a lens until the eye becomes better. Do not use eye drops for longer than recommended by your doctor, as it may increase the risk of cataracts (clouding of the eye) and increase the risk of a second infection. So, inform your doctor immediately if you notice any persistent visual disturbances while using this medicine. It is advised to check with your doctor before using Genfour-LP Eye Drops 5 ml if you are pregnant or breastfeeding. Avoid driving or operating machines since the administration of eye drops of Genfour-LP Eye Drops 5 ml cause blurred vision for a while after use.

Drug-Drug Interactions

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MoxifloxacinProcainamide
Critical
MoxifloxacinHalofantrine
Critical

Drug-Drug Interactions

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MoxifloxacinProcainamide
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using procainamide together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Procainamide can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
MoxifloxacinHalofantrine
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using Halofantrine together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Halofantrine is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
MoxifloxacinDisopyramide
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using Disopyramide together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Disopyramide is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting your doctor.
MoxifloxacinSotalol
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Combining Genfour-LP Eye Drops 5 ml with Sotalol can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sotalol with Genfour-LP Eye Drops 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MoxifloxacinDronedarone
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using dronedarone together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Dronedarone is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
MoxifloxacinAmiodarone
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Taking Amiodarone and Genfour-LP Eye Drops 5 ml may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone and Genfour-LP Eye Drops 5 ml is not recommended as it can lead to an interaction; it can be taken if advised by a doctor. If you get dizziness, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
MoxifloxacinQuinidine
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using quinidine together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Quinidine can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
MoxifloxacinZiprasidone
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using Genfour-LP Eye Drops 5 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Ziprasidone is not recommended as it can lead to an interaction; it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
MoxifloxacinBepridil
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Coadministration of Genfour-LP Eye Drops 5 ml with Bepridil may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Bepridil is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
MoxifloxacinSaquinavir
Critical
How does the drug interact with Genfour-LP Eye Drops 5 ml:
Using saquinavir together with Genfour-LP Eye Drops 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Genfour-LP Eye Drops 5 ml with Saquinavir can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to maintain good hygiene to keep your eyes clean and irritant-free.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • Know your allergy triggers, such as pollen, dust, and other factors.
  • Sleep for at least six to eight hours to rejuvenate your eyes naturally.
  • Wash your eyes with clean water at least two to three times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Wash your hands thoroughly, and do not touch the dropper before using drops to avoid contamination.
  • Reduce screen time (by avoiding watching tv or phone) and use sunglasses while going into the sunlight.
  • Avoid alcoholic beverages as they can make you dehydrated and affect your sleep. This effect can also affect your body’s ability to fight off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS AND CORTICOSTEROIDS

Genfour-LP Eye Drops 5 ml Substitute

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Alcohol

Caution

Do not take alcohol while using Genfour-LP Eye Drops 5 ml as it may affect your ability to fight infections.

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Pregnancy

Caution

Inform your doctor before receiving Genfour-LP Eye Drops 5 ml if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Genfour-LP Eye Drops 5 ml; your doctor will decide whether Genfour-LP Eye Drops 5 ml can be taken by breastfeeding mothers or not.

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Driving

Caution

Genfour-LP Eye Drops 5 ml may cause side effects like blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Caution

Inform your doctor before receiving the Genfour-LP Eye Drops 5 ml if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Inform your doctor before receiving the Genfour-LP Eye Drops 5 ml if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Genfour-LP Eye Drops 5 ml should be used with caution in children. It is not recommended for use in newborns.

FAQs

Genfour-LP Eye Drops 5 ml is used to treat bacterial eye infections or eye discomfort. It is also used in patients who have undergone eye surgeries. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns.
Genfour-LP Eye Drops 5 ml contains Moxifloxacin and Loteprednol. Moxifloxacin is an antibiotic that prevents bacterial cells from dividing and repairing, thereby killing the bacteria. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers), making the eye red, swollen and itchy. Collectively, Genfour-LP Eye Drops 5 ml helps relieve and treat symptoms of bacterial eye infections.
You are not recommended to stop using Genfour-LP Eye Drops 5 ml without consulting your doctor even if you feel better, as it may increase pressure in the eyes and may lead to loss of vision. Your symptoms may improve before the infection is completely cured. Therefore, use Genfour-LP Eye Drops 5 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Genfour-LP Eye Drops 5 ml, please consult your doctor.
If you are using other eye drops along with Genfour-LP Eye Drops 5 ml, maintain an interval of at least 10 minutes before administering other medicines in the same eye to avoid dilution.
Genfour-LP Eye Drops 5 ml is generally prescribed for seven days. You should take this medicine for a duration given by your doctor. Avoid prolonged use, as it may cause cataracts (clouding of the eye) and increase the second infection risk. If you use Genfour-LP Eye Drops 5 ml for longer than ten days, you may need frequent vision tests to check the pressure inside your eyes.
Genfour-LP Eye Drops 5 ml can cause blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.
Avoid prolonged use, as it may cause cataracts (clouding of the eye) and increase the risk of a second infection. Also, do not wear contact lenses while using Genfour-LP Eye Drops 5 ml.
Genfour-LP Eye Drops 5 ml is for ophthalmic use only. Wash your hands thoroughly before and after using Genfour-LP Eye Drops 5 ml. To use Genfour-LP Eye Drops 5 ml, lie down and tilt your head back. Gently pull your lower eyelid down with your index finger to create a small pocket. Place the prescribed number of drops into the pocket of your lower eyelid. Keep your eyes closed for 1-2 minutes. After use, replace the outer cap tightly. Be careful not to touch the tip of the bottle to your eye, eyelids, or surrounding areas, as this may contaminate Genfour-LP Eye Drops 5 ml.
The common side effects of Genfour-LP Eye Drops 5 ml include redness in the eyes, blurred vision, burning or stinging sensation, and eye discomfort. These side effects do not require medical attention and gradually resolve over time. If the side effects persist or worsen, please consult your doctor.
You should not use Genfour-LP Eye Drops 5 ml if you are allergic to any of its ingredients. Also, avoid using Genfour-LP Eye Drops 5 ml if you have a damaged cornea, eye ulcers, an eye infection with pus, open lesions in the eye, and glaucoma (a condition where the pressure inside the eye is higher than normal).
Avoid wearing contact lenses while using Genfour-LP Eye Drops 5 ml, as it may contain ingredients like Benzalkonium chloride, which can change the colour of your lenses. This may also increase the risk of eye irritation. If you wear contact lenses, inform your doctor before using Genfour-LP Eye Drops 5 ml.
If you suspect an overdose of Genfour-LP Eye Drops 5 ml, rinse your eyes with clean water immediately. Avoid using more drops until you have consulted your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - GEN0545

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