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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Gcolate-1 Tablet is used to treat peptic ulcers in adults and children above 12 years. It is also used to treat severe drooling caused by certain neurologic disorders (cerebral palsy) in children 3 to 16 years of age. It contains Glycopyrrolate, which decreases stomach acid and saliva production. In some cases, it may cause dry mouth, vomiting, flushing, headache, and nasal congestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Icon Life Sciences

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Gcolate-1 Tablet

Gcolate-1 Tablet belongs to the group of medications called ‘anticholinergics’ primarily used to treat peptic ulcers in adults and children above 12 years. It is also used to treat severe drooling caused by certain neurologic disorders (cerebral palsy) in children 3 to 16 years of age. Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. 

Gcolate-1 Tablet contains ‘Glycopyrrolate’, which decreases stomach acid and saliva production by blocking the activity of a certain natural substance in the body.  Thereby helps treat peptic ulcers and drooling.

You are advised to take Gcolate-1 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition.  In some cases, Gcolate-1 Tablet may cause dry mouth, vomiting, flushing, headache, and nasal congestion. Most of these side effects of Gcolate-1 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any of the components in Gcolate-1 Tablet . Consult your doctor if you are pregnant or breastfeeding. Gcolate-1 Tablet may cause sleepiness and blurred vision, do not drive or operate machinery unless you are alert. Let your doctor know if you are taking any prescription and non-prescription medications, including vitamins and herbal supplements.

Uses of Gcolate-1 Tablet

Treatment of Peptic ulcers, Drooling (excessive salivation)

Medicinal Benefits

Gcolate-1 Tablet belongs to the group of medications called ‘anticholinergics’ primarily used to treat peptic ulcers in adults and children above 12 years. It is also used to treat severe drooling caused by certain neurologic disorders (cerebral palsy) in children 3 to 16 years of age. Gcolate-1 Tablet contains ‘Glycopyrrolate’, which decreases stomach acid and saliva production by blocking the activity of a certain natural substance in the body.  Thereby helps treat peptic ulcers and drooling.

Directions for Use

Swallow it as a whole with water; do not crush or chew the tablet.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gcolate-1 Tablet

  • Dry mouth
  • Vomiting
  • Flushing
  • Constipation
  • Nasal congestion

Drug Warnings

If you are allergic to Gcolate-1 Tablet or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Gcolate-1 Tablet . Let your doctor know if you are taking any prescription and non-prescription medications, including vitamins and herbal supplements. Inform your doctor if you have autonomic neuropathy, hyperthyroidism, urination problems, a blockage in your stomach or intestines, severe constipation, ulcerative colitis, glaucoma, myasthenia gravis, bleeding problems, blood circulation problems, enlarged prostate, liver/ kidney diseases.

Drug Interactions

Drug-Drug Interaction: Gcolate-1 Tablet may interact with other anticholinergics (atropine), cholinesterase inhibitors (neostigmine, pyridostigmine), anticonvulsants (topiramate), antihistamines (diphenhydramine).

Drug-Food Interaction: No interactions found/established.

Drug-Diseases Interaction: If you have urination problems, gastrointestinal blockage, severe constipation, ulcerative colitis, glaucoma, heart and blood circulation problems, inform your doctor before taking Gcolate-1 Tablet .

Drug-Drug Interactions Checker List

  • ATROPINE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • TOPIRAMATE
  • DIPHENHYDRAMINE

Habit Forming

No

Diet & Lifestyle Advise

Peptic ulcers:

  • ​​​​​Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. 

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating to prevent acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practice relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

Disease/Condition Glossary

Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

Drooling: It is a condition in which excessive saliva flows out of the mouth involuntarily. Drooling can occur due to medical or neurological conditions such as cerebral palsy.

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Alcohol

Caution

It is not known if alcohol interacts with Gcolate-1 Tablet . Please consult your doctor.

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Pregnancy

Caution

Consult your doctor before taking Gcolate-1 Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Gcolate-1 Tablet if you are breastfeeding; your doctor will decide whether Gcolate-1 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Gcolate-1 Tablet may cause sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

If you have liver problems, please inform your doctor before taking this medicine.

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Kidney

Caution

If you have kidney problems, please inform your doctor before taking this medicine.

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Children

Caution

Tablet: It is not recommended for children as safety and effectiveness have not been established.Oral solution: It can be given to children above 3 years if prescribed by a doctor. The safety and effectiveness have not been established in children below 3 years.

Country of origin

INDIA
Other Info - GCO0006

Author Details

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FAQs

Gcolate-1 Tablet is used for the treatment of Peptic ulcers, Drooling (excessive salivation).
Dry mouth could be a side effect of Gcolate-1 Tablet . Limiting caffeine intake, avoiding smoking, and drinking water regularly, chewing sugar-free gum/candy might stimulate saliva, thereby preventing drying of the mouth.
Do not stop taking Gcolate-1 Tablet on your own. You are advised to take Gcolate-1 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be hesitant to speak with your doctor if you experience any difficulty while taking Gcolate-1 Tablet .
Gcolate-1 Tablet may cause your child to sweat less, leading to overheating and heat stroke. Avoid doing things that may cause you to overheat, such as exercising. Consult your doctor if you notice hot, red skin, fast, weak pulse, fast, shallow breathing, fever, or decreased alertness.
Gcolate-1 Tablet may cause constipation. Eat fibre rich diet and drink plenty of water.
Gcolate-1 Tablet decreases stomach acid and saliva production by blocking the activity of a certain natural substance in the body.

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