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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Frusimed 20mg/50mg Tablet is used to remove excess water from the body. Besides this, it also maintains the level of potassium in the bloodstream and prevents hypertension (high blood pressure due to oedema (fluid retention). It works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack, stroke or angina (chest pain) in future. Sometimes, you may experience low blood pressure (hypotension), dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness.
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ORAL

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Not Returnable

About Frusimed 20mg/50mg Tablet

Frusimed 20mg/50mg Tablet used to remove excess water from the body. Besides this, it also maintains the level of potassium in the bloodstream and prevents hypertension (high blood pressure due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, which may be accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia) and swelling in other areas of the hands or abdomen.

Frusimed 20mg/50mg Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack, stroke or angina (chest pain) in future.

You can take Frusimed 20mg/50mg Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, crush, or break it. Your doctor will advise you how often you take Frusimed 20mg/50mg Tablet based on your medical condition. Sometimes, you may experience low blood pressure (hypotension), dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness. Most of these side effects of Frusimed 20mg/50mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Frusimed 20mg/50mg Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of getting heart disease and stroke. Inform your doctor if you are suffering from any kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Frusimed 20mg/50mg Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to Frusimed 20mg/50mg Tablet. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body.

Uses of Frusimed 20mg/50mg Tablet

Treatment of Oedema (fluid overload), Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

When you take Frusimed 20mg/50mg Tablet, it helps in losing out excess fluids from the body by increasing the production of urine. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. In addition, this relieves oedema and helps you carry out your daily activities more efficiently.

How Frusimed 20mg/50mg Tablet Works

Frusimed 20mg/50mg Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack, stroke or angina (chest pain) in future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Frusimed 20mg/50mg Tablet

  • Electrolyte disturbances

  • Dehydration

  • Hyponatremia (low sodium concentration in the blood)

  • Hypochloraemia (low blood levels of chloride)

  • Hypokalaemia (low potassium levels)

  • Increased blood cholesterol

  • Increased uric acid

  • Low blood pressure (hypotension)

  • Orthostatic hypotension

  • Increased urine volume

  • Headache

  • Drowsiness/somnolence

What if I have taken an overdose of Frusimed 20mg/50mg Tablet

Do not take more than the prescribed dose of Frusimed 20mg/50mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Frusimed 20mg/50mg Tablet should not be given to the people allergic to Frusimed 20mg/50mg Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Frusimed 20mg/50mg Tablet can pass into breast milk, but its effect on the baby is not known, so it is better to tell your doctor if you are taking Frusimed 20mg/50mg Tablet and breastfeeding. Frusimed 20mg/50mg Tablet may cause vocal changes so special attention must be given to the patients using Frusimed 20mg/50mg Tablet and whose voice is significant for their work (like actors, singers, or teachers). Hypovolaemia or dehydration with electrolyte and acid-base disturbances must be corrected before using Frusimed 20mg/50mg Tablet.

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Frusimed 20mg/50mg Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Frusimed 20mg/50mg Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Frusimed 20mg/50mg Tablet:
Coadministration of Amiloride with Frusimed 20mg/50mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Frusimed 20mg/50mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
FurosemideZiprasidone
Critical
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking Ziprasidone with Frusimed 20mg/50mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Frusimed 20mg/50mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
SpironolactoneEnalapril
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking enalapril with Frusimed 20mg/50mg Tablet can increase the risk of high potassium levels in the blood.

How to manage the interaction:
Taking Enalapril with Frusimed 20mg/50mg Tablet is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, tingling in your hands and feet, or a feeling of heaviness in your legs. Do not stop taking any medication without a doctor's advice.
SpironolactoneCiclosporin
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking Frusimed 20mg/50mg Tablet with ciclosporin may increase potassium levels in the blood.

How to manage the interaction:
Although taking Frusimed 20mg/50mg Tablet and ciclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness. Do not stop using any medications without consulting a doctor.
SpironolactonePotassium chloride
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking Frusimed 20mg/50mg Tablet with Potassium chloride may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Potassium chloride with Frusimed 20mg/50mg Tablet can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneAzilsartan medoxomil
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Coadministration of Azilsartan medoxomil with Frusimed 20mg/50mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking Frusimed 20mg/50mg Tablet and Azilsartan medoxomil together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, weakness, confusion, tingling of the hands and feet, or palpitations. Do not stop using any medications without consulting a doctor.
SpironolactoneLosartan
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Coadministration of Losartan with Frusimed 20mg/50mg Tablet can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Frusimed 20mg/50mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneTizanidine
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking Frusimed 20mg/50mg Tablet with tizanidine can cause low blood pressure.

How to manage the interaction:
Although taking Frusimed 20mg/50mg Tablet and tizanidine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not discontinue any medications without consulting a doctor.
SpironolactoneBenazepril
Severe
How does the drug interact with Frusimed 20mg/50mg Tablet:
Taking Frusimed 20mg/50mg Tablet with benazepril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Frusimed 20mg/50mg Tablet and benazepril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.

  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.

  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.

  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.

  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.

  • Avoid consumption of too much salt or salty food.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise like walking improves your blood flow.

  • When possible, elevate your legs or the swollen area on a chair or pillows.

  • Avoid standing or sitting for extended periods of time.

  • Avoid chronic stress as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Alcohol

Caution

You are recommended not to consume alcohol along with Frusimed 20mg/50mg Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Frusimed 20mg/50mg Tablet must not be taken during pregnancy.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Frusimed 20mg/50mg Tablet.

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Driving

Unsafe

It is not recommended to drive after taking Frusimed 20mg/50mg Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Frusimed 20mg/50mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Frusimed 20mg/50mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Unsafe

Frusimed 20mg/50mg Tablet is not recommended for children below 12 years of age.

FAQs

Frusimed 20mg/50mg Tablet is used to treat hypertension (high blood pressure and oedema (fluid retention). It helps to remove excess water from the body.
Frusimed 20mg/50mg Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack, stroke or angina (chest pain) in future.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.
You should closely monitor your blood pressure, renal function and electrolytes within 4-6 weeks of commencing therapy. Besides this, frequent checks of the potassium level are required in patients with kidney failure and with creatinine clearance below 60 ml/min per.
If your leg (foot, ankle) or any other body's part swelling, you need to visit any physician or cardiologist who could perform an ultrasound examination of your leg veins and an ultrasound of your heart (echocardiogram-ECG).
Store Frusimed 20mg/50mg Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Do not take Frusimed 20mg/50mg Tablet if you are allergic to any of its components, have low blood pressure (less than 90 mm of Hg), have had a heart attack, or have kidney disease (with creatinine clearance less than 30 mL/min). Besides this, it is contraindicated in cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
Frusimed 20mg/50mg Tablet is a combination medicine used to treat oedema (fluid overload) and hypertension (high blood pressure).
Yes, Frusimed 20mg/50mg Tablet is safe if taken in the dose and duration prescribed by the doctor.
Frusimed 20mg/50mg Tablet may cause dizziness as a side effect. Do not drive or operate machinery if you experience dizziness.
Frusimed 20mg/50mg Tablet contains furosemide which may increase uric acid levels leading to gout. Consult the doctor if you experience sudden severe pain in a joint (usually your big toe).

Manufacturer/Marketer address

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001
Other Info - FR53516

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