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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Frenin Injection 1 ml is used to treat hypotension (low blood pressure) caused by spinal anaesthesia, circulatory failure or certain other medicines. It also treats low blood pressure during surgery or after an injury.  It contains phenylephrine, which constricts and narrows blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate. Common side effects of Frenin Injection 1 ml are headache, vomiting, sweating, nervousness, tremors, shortness of breath, difficulty passing urine or irregular heartbeat.
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Composition :

PHENYLEPHRINE-10MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Frenin Injection 1 ml

Frenin Injection 1 ml belongs to a class of medications called anti-hypotensives used to treat hypotension (low blood pressure) caused by spinal anaesthesia, circulatory failure or certain other medicines. Also, it is used to treat low blood pressure during surgery or after an injury. Hypotension is a condition in which the blood flows through the blood vessels at lower than normal pressures. Low blood pressure symptoms include tiredness, dizziness, light-headedness, loss of consciousness, nausea, depression, blurry vision, or clammy (wet or sweaty) skin.

Frenin Injection 1 ml contains Phenylephrine that works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

Frenin Injection 1 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience headache, vomiting, sweating, nervousness, tremor, shortness of breath, difficulty in passing urine or irregular heartbeat. Most of these side effects of Frenin Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Phenylephrine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Frenin Injection 1 ml. Discuss with your doctor if you want to drive or operate machinery after receiving Frenin Injection 1 ml. Caution is advised when drinking alcohol while you are receiving Frenin Injection 1 ml.

Uses of Frenin Injection 1 ml

Treatment of Hypotension (low blood pressure)

Directions for Use

Frenin Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Frenin Injection 1 ml contains Phenylephrine, an anti-hypotensive agent used to treat low blood pressure caused by spinal anaesthesia, circulatory failure or certain other medicines. Also, it is used to treat low blood pressure during surgery or after an injury. It works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

How Frenin Injection 1 ml Works

Frenin Injection 1 ml contains Phenylephrine that works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Frenin Injection 1 ml

  • Headache
  • Vomiting
  • Sweating
  • Nervousness
  • Tremor
  • Shortness of breath
  • Difficulty in passing urine
  • Irregular heartbeat

What if I have taken an overdose of Frenin Injection 1 ml

Since Frenin Injection 1 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Frenin Injection 1 ml may cause feeling of fullness in the head, pounding or rapid pulse, tingling in the arms or legs, and vomiting.

Drug Warnings

Please tell your doctor if you are allergic to Phenylephrine or other medicines. If you are pregnant or breastfeeding, please inform your doctor before receiving Frenin Injection 1 ml. Discuss with your doctor if you want to drive or operate machinery after receiving Frenin Injection 1 ml. Caution is advised when drinking alcohol while you are receiving Frenin Injection 1 ml. Frenin Injection 1 ml should not be given to you if you are taking or have taken monoamine oxidase (MAO) inhibitor medicines (used for depression) in the past 14 days.

Drug-Drug Interactions

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PhenylephrinePropofol
Critical
PhenylephrineTranylcypromine
Critical

Drug-Drug Interactions

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PhenylephrinePropofol
Critical
How does the drug interact with Frenin Injection 1 ml:
Taking Frenin Injection 1 ml with Propofol may lead to increased levels of Frenin Injection 1 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Frenin Injection 1 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Frenin Injection 1 ml:
Taking Tranylcypromine with Frenin Injection 1 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Frenin Injection 1 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Selegiline with Frenin Injection 1 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Frenin Injection 1 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Frenin Injection 1 ml:
Taking Furazolidone with Frenin Injection 1 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Frenin Injection 1 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Frenin Injection 1 ml only after 14 days of stopping Furazolidone.
PhenylephrineSevoflurane
Critical
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Sevoflurane can increase the levels of Frenin Injection 1 ml and lead to side effects.

How to manage the interaction:
Taking Frenin Injection 1 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineMethoxyflurane
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Methoxyflurane can increase the side effects of Methoxyflurane.

How to manage the interaction:
There may be a possibility of interaction between Frenin Injection 1 ml and Methoxyflurane, but it can be taken if prescribed by a doctor. Do not discontinue any medications without doctor's advice.
PhenylephrineErgotamine
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Ergotamine and Frenin Injection 1 ml, can raise the risk of side effects including high blood pressure.

How to manage the interaction:
Although taking Frenin Injection 1 ml and Ergotamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of your fingers or toes, pale or cold skin, tightness in your chest, a severe headache, breathing difficulty, irregular heartbeat, vision disturbances, confusion, unclear speech, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
PhenylephrineHalothane
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Halothane may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Frenin Injection 1 ml with Halothane together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms like lightheadedness, fainting, irregular heart beat, dizziness, consult the doctor. Do not discontinue any medications without a doctor's advice.
PhenylephrineTopiramate
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Frenin Injection 1 ml.

How to manage the interaction:
Although there is a possible interaction between Frenin Injection 1 ml and Topiramate, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
PhenylephrineDoxepin
Severe
How does the drug interact with Frenin Injection 1 ml:
Taking Doxepin and Frenin Injection 1 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Doxepin and Frenin Injection 1 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms, contact your doctor immediately. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.
  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
  • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
  • Eat foods rich in folates such as beans, asparagus, lentils, leafy greens, citrus fruits, liver, and eggs.
  • Try to eat smoked fish, canned soup, pickled items, cottage cheese, and olives, as salty foods can also increase blood pressure.
  • Take frequent breaks if you exercise outdoors in extreme heat.
  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES

Frenin Injection 1 ml Substitute

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Alcohol

Caution

You are advised to be careful when drinking alcohol while you are receiving Frenin Injection 1 ml. However, if you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Frenin Injection 1 ml in pregnancy. Hence, if you are pregnant or planning for pregnancy, inform your doctor before receiving Frenin Injection 1 ml.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Frenin Injection 1 ml on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Frenin Injection 1 ml.

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Driving

Consult your doctor

Discuss with your doctor if you want to drive or operate machinery after receiving Frenin Injection 1 ml.

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Liver

Consult your doctor

If you have a pre-existing history of liver disease, inform your doctor before receiving Frenin Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Frenin Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

If you have any concerns regarding the use of Frenin Injection 1 ml in children, please consult your doctor.

FAQs

Frenin Injection 1 ml is used to treat Hypotension (low blood pressure).
Frenin Injection 1 ml contains Phenylephrine that works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.
Phenylephrine in Frenin Injection 1 ml may worsen heart failure due to constriction of blood vessels. Therefore, inform your doctor if you have heart failure or any other heart problem before receiving Frenin Injection 1 ml.
Frenin Injection 1 ml may cause a headache as a temporary side effect. However, if the condition persists or worsens, please inform your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - FRE0005

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