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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:47 PM IST
Flexabenz Plus Tablet is used to relieve pain due to muscle spasms. It contains cyclobenzaprine and aceclofenac which help improve muscle movements and inhibit certain chemical messengers that cause pain. In some cases, this medicine may cause side effects such as nausea, dry mouth, stomach pain, diarrhoea, heartburn, loss of appetite, dizziness and sleepiness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Flexabenz Plus Tablet

Flexabenz Plus Tablet belongs to a class of medicine known as a pain killer. It is primarily used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain), gout, pinched vein, acute pain and chronic pain, muscle spasms. It relieves the pain and relaxes the muscles. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Flexabenz Plus Tablet is a combination of two drugs: Cyclobenzaprine (muscle relaxant) and aceclofenac (NSAID). Cyclobenzaprine is a muscle relaxant and works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins (PG). By blocking the effect of chemical messenger aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Take Flexabenz Plus Tablet as prescribed by your doctor. You are advised to take Flexabenz Plus Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, dryness in the mouth, stomach pain, diarrhea, heartburn, loss of appetite (feeling not hungry), dizziness and sleepiness. Most of these side effects of Flexabenz Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Flexabenz Plus Tablet if you are allergic to Flexabenz Plus Tablet or any of its contents. Flexabenz Plus Tablet should not be taken in the conditions like liver disease, kidney disease, asthma and high blood pressure. Flexabenz Plus Tablet may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert. If you are pregnant or breastfeeding, please inform your doctor before starting Flexabenz Plus Tablet . Flexabenz Plus Tablet should not be used in children below 18 years of age as safety and efficacy have not established.

Uses of Flexabenz Plus Tablet

Treatment of Osteoarthritis, Rheumatoid arthritis, Gouty arthritis, Pinched vein, Ankylosing spondylitis, Acute pain, Chronic low back pain, Muscle spasms.

Medicinal Benefits

Flexabenz Plus Tablet is a combination of two drugs: Cyclobenzaprine (muscle relaxant) and aceclofenac (NSAID). Flexabenz Plus Tablet is used for the treatment of osteoarthritis, rheumatoid arthritis, gout and ankylosing spondylitis, pinched vein, acute pain, chronic low back pain and muscle spasms. Cyclobenzaprine works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandin' (PG). These chemicals are produced at injury sites and cause pain and swelling. By blocking the effect of chemicals, aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thus, Flexabenz Plus Tablet relieves the pain and relax the muscles.

Directions for Use

Take Flexabenz Plus Tablet with or after food. Swallow it as a whole with a glass of water, do not chew or break it. Based on your medical condition, your doctor will decide how long you need to take Flexabenz Plus Tablet .

Storage

Store in a cool and dry place away from sunlight

Side Effects of Flexabenz Plus Tablet

  • Nausea
  • Dryness in mouth
  • Stomach pain
  • Diarrhea
  • Heartburn
  • Loss of appetite (feeling not hungry)
  • Dizziness
  • Sleepiness.

Drug Warnings

Flexabenz Plus Tablet should not be taken if you are known to be allergic to Flexabenz Plus Tablet or any other medicines. Flexabenz Plus Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Flexabenz Plus Tablet . Inform your doctor if you have thyroid disorder (hyperthyroidism), stomach ulcers, have suffered bleeding problems, clotting problems, severe heart, liver or kidney problems.  Please talk to your doctor immediately if you experience mood swings, depression or if you have any suicidal thoughts. Your doctor may advise you to undergo regular blood tests to monitor liver function. Inform your doctor before taking Flexabenz Plus Tablet if you have or had disorders of the stomach, blood circulation problem to brain, asthma, porphyria, diabetes, high blood pressure. Flexabenz Plus Tablet may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert. If you are pregnant or breastfeeding, please inform your doctor before starting Flexabenz Plus Tablet . Flexabenz Plus Tablet should not be used in children below 18 years of age as safety and efficacy have not established.

Drug Interactions

Drug-Drug Interactions: Flexabenz Plus Tablet may have interaction with heart disease (digoxin), pain killer (aspirin, morphine), blood thinner (clopidogrel), antiparkinson’s disease (selegiline), antidepressant (lithium), blood pressure-lowering medicines (captopril), water pills/diuretics (amiloride), medicines for skin disease (tacrolimus), antiallergic (chlorpheniramine), sleeping pill (zolpidem).

Drug-Food Interactions: Avoid alcohol consumption while taking Flexabenz Plus Tablet as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Flexabenz Plus Tablet may have interactions with allergy, kidney disease, asthma, ulcer and heart disease.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • ASPIRIN
  • MORPHINE
  • CLOPIDOGREL
  • SELEGILINE
  • LITHIUM
  • CAPTOPRIL
  • AMILORIDE
  • TACROLIMUS
  • CHLORPHENIRAMINE
  • ZOLPIDEM

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

Flexabenz Plus Tablet is not recommended for use in patients with a history of gastrointestinal ulcers or bleeding since it may worsen the patient's condition.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to hunched-forward posture, pain and back and joints.

Gout: It is caused due to deposits of uric acid crystals in the joints, which leads to pain and inflammation in the joints. Symptoms include pain, swelling and redness in the joints, mostly the big toe.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Flexabenz Plus Tablet as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking Flexabenz Plus Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Very-small amounts of Flexabenz Plus Tablet pass into breast milk. However, consult your doctor before taking Flexabenz Plus Tablet , your doctor will decide whether Flexabenz Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Flexabenz Plus Tablet may cause drowsiness, sleepiness, fatigue, dizziness and visual disturbance it is advisable to you do not drive unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Avoid taking Flexabenz Plus Tablet if you have severe kidney disease.

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Children

Unsafe

Flexabenz Plus Tablet should not be given to children for 18 years of age as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - FLE0162

Author Details

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FAQs

Flexabenz Plus Tablet is used to relieve pain due to muscle spasms in conditions like spondylitis, osteoarthritis, rheumatoid arthritis, gout, and pinched veins.
Flexabenz Plus Tablet is a combination of two drugs: Cyclobenzaprine (Muscle relaxant) and aceclofenac (NSAID). Cyclobenzaprine works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby helping relieve pain due to muscle spasms. Aceclofenac blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical 'prostaglandin' (PG). These chemicals are produced at injury sites and cause pain and swelling. By blocking the effect of chemicals, aceclofenac helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thus, Flexabenz Plus Tablet relieves the pain and relax the muscles.
Diarrhea might be a side-effect of Flexabenz Plus Tablet . Drink enough fluids and eat fiber-rich food if you experience diarrhea. Inform your doctor if diarrhea continues and you observe signs of dehydration, like dark colored with less urination and strong-smelling urine. Do not take anti-diarrheal medicine on your own.
Yes, the use of Flexabenz Plus Tablet can lead to dry mouth. If you feel dry mouth, drink plenty of water. If your lips are also dry you may use lip balm. Try to prevent foods that are spicy, salty and acidic (like lemons).
Flexabenz Plus Tablet is normally used for the short term and can be stopped if there is no pain. Although, it should be persisted if recommended by the doctor.
Ankylosing spondylitis is arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.
Yes, Flexabenz Plus Tablet can cause damage to the kidneys, especially with prolonged use and it is not advised if you have pre-existing kidney disease. If you have any pre-existing kidney conditions, it's important to consult your doctor before using Flexabenz Plus Tablet .
No, taking a higher than the recommended dose of Flexabenz Plus Tablet will not make it more effective and can actually increase the risk of side effects. If you are experience increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor.
Yes, Flexabenz Plus Tablet can cause sleepiness as a side effect. It's important to be cautious when taking Flexabenz Plus Tablet , especially if you need to drive, operate machinery, or perform tasks that require alertness. If you experience excessive drowsiness, it's best to avoid such activities until you know how the medication affects you.
Store Flexabenz Plus Tablet at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.
Take it with food to avoid stomach upset or as advised by your doctor. But take it at the same time every day. Swallow it whole with a glass of water and do not chew or break it.
The common side effects of Flexabenz Plus Tablet are nausea, dryness in the mouth, stomach pain, diarrhoea, heartburn, loss of appetite (feeling not hungry), dizziness and sleepiness. If any of these side effects persist or worsen, please consult your doctor.
Flexabenz Plus Tablet should not be used if you are allergic to Flexabenz Plus Tablet . Inform your doctor if you have liver disease, kidney disease, asthma, or high blood pressure. Consult your doctor before starting the Flexabenz Plus Tablet .
No, Flexabenz Plus Tablet is not recommended for children under 18 years of age. It's important to consult your doctor for appropriate medications if a child needs treatment for muscle spasms or pain.

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