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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fibractiv 105 mg Tablet is used to treat raised or increased cholesterol levels or fat/oils. It contains Fenofibrate, which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases the levels of HDL (good cholesterol). Some people may experience nausea, chest pain, vomiting, diarrhoea, drowsiness, muscle pain, redness/swelling in the legs and increased liver enzymes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

FENOFIBRIC ACID

Composition :

FENOFIBRATE-105MG

Manufacturer/Marketer :

Cogentrix Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Fibractiv 105 mg Tablet

Fibractiv 105 mg Tablet is used to treat raised or increased cholesterol levels or fat/oils. Hyperlipidemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased level of bad cholesterol leads to a high risk of heart attack and stroke in future, especially for heart disease patients.

Fibractiv 105 mg Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Always take the Fibractiv 105 mg Tablet exactly as prescribed by your doctor. Some people may experience nausea, chest pain, vomiting, diarrhoea, drowsiness, muscle pain, redness/swelling in the legs and increased liver enzymes. Most of these side effects of Fibractiv 105 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Fibractiv 105 mg Tablet for as long as your doctor has prescribed it. Do not use Fibractiv 105 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using Fibractiv 105 mg Tablet if you are pregnant or breastfeeding. Fibractiv 105 mg Tablet is not recommended for children under the age of 18, as the safety and effectiveness were not established. Avoiding alcohol is recommended to rule out any possibility of side effects.

Uses of Fibractiv 105 mg Tablet

Treatment of Hyperlipidemia or High cholesterol.

Directions for Use

Swallow Fibractiv 105 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Fibractiv 105 mg Tablet contains 'fenofibrate', which is used along with a proper diet to help lower 'bad cholesterol' (LDL, TG -triglycerides) and raise 'good cholesterol' (HDL) in the blood. Fibractiv 105 mg Tablet is also used with statins to lower raised cholesterol. Besides this, Fibractiv 105 mg Tablet also helps in the treatment of raised cholesterol in diabetes and high blood pressure patients as well.

How Fibractiv 105 mg Tablet Works

Fibractiv 105 mg Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fibractiv 105 mg Tablet

  • Muscle pain

  • Stuffy/runny nose

  • Headache

  • Joint pain

  • Increased liver enzymes

What if I have taken an overdose of Fibractiv 105 mg Tablet

Do not take more than the prescribed dose of Fibractiv 105 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Before taking the Fibractiv 105 mg Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Inform your doctor if you are suffering from bladder problems, gallstones, liver disease, kidney disease, or muscle problems (like muscle pain, myopathy, or rhabdomyolysis). If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Keep your doctor informed about your health condition and all the medicines you are taking before taking Fibractiv 105 mg Tablet to rule out any side effects. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness. Fibractiv 105 mg Tablet is not recommended in children below 18 years of age.

Drug-Drug Interactions

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FenofibratePravastatin
Severe
FenofibrateDicoumarol
Severe

Drug-Drug Interactions

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FenofibratePravastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
When Fibractiv 105 mg Tablet 10's is used with pravastatin, it increases the chance of adverse effects such as liver damage and rhabdomyolysis, an uncommon but deadly illness characterised by the destruction of skeletal muscle tissue. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Co-administration of Fibractiv 105 mg Tablet 10's with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. Inform a doctor immediately, if you have unexplained muscular pain, soreness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, or yellowing of the skin or eyes, consult the doctor immediately.
FenofibrateDicoumarol
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
co-administration of Fibractiv 105 mg Tablet 10's with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.

How to manage the interaction:
Taking Fibractiv 105 mg Tablet 10's with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
FenofibrateWarfarin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
Taking Warfarin together with Fibractiv 105 mg Tablet 10's can increase the risk of bleeding.

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet 10's and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
FenofibrateSimvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
The use of Fibractiv 105 mg Tablet 10's and simvastatin can increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue), rhabdomyolysis can cause kidney damage. If you are elderly or have preexisting kidney disease, the risk may increase.

How to manage the interaction:
Co-administration of Fibractiv 105 mg Tablet 10's and simvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibratePitavastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
Taking Fibractiv 105 mg Tablet 10's with Pitavastatin can increase the risk of muscle problems like liver damage and rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Fibractiv 105 mg Tablet 10's, you can take these medicines together if prescribed by a doctor. However, if you experience unexpected bruising or bleeding, skin rash, itching, exhaustion, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without consulting a doctor.
FenofibrateMipomersen
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
Mipomersen may cause liver problems and using it with Fibractiv 105 mg Tablet 10's may increase that risk.

How to manage the interaction:
There may be a possibility of interaction between Fibractiv 105 mg Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
FenofibrateCerivastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
When Fibractiv 105 mg Tablet 10's is used with cerivastatin, the risk of adverse effects such as liver damage and rhabdomyolysis, an uncommon but serious illness involving the breakdown of skeletal muscle tissue, increases. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet 10's and Cerivastatin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience unexplained muscular pain, soreness, or weakness while taking these drugs, inform a doctor immediately, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateNicotine
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
The combined use of Nicotine and Fibractiv 105 mg Tablet 10's can increase the blood levels and effects of nicotine. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Nicotine and Fibractiv 105 mg Tablet 10's can lead to an interaction, it can be taken if advised by a doctor. If you experience any symptoms like irritation and burning sensation in the mouth and throat, increased salivation, nausea, abdominal pain, vomiting and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting the doctor.
FenofibrateAtorvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
When atorvastatin is used with Fibractiv 105 mg Tablet 10's, it increases the risk of side effects such as liver damage, rhabdomyolosis (uncommon illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet 10's and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FenofibrateAtorvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet 10's:
Coadministration of Fibractiv 105 mg Tablet 10's with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet 10's and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eating a proper diet (such as a low-cholesterol/low-fat diet) and other lifestyle changes that may help this medication work better include exercising, losing weight if overweight and stopping smoking.

  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.

  • Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.

  • Contact your healthcare provider immediately if you notice slurred speech, confusion, severe weakness or difficulty breathing.

 

Habit Forming

No

Therapeutic Class

ANTILIPEMICS
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Alcohol

Caution

Avoid drinking alcohol as it can raise liver enzymes and liver functions test (LFT), thereby damaging your liver.

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Pregnancy

Caution

Fibractiv 105 mg Tablet is a Category C risk medicine; talk with your doctor if you’re pregnant or planning to become pregnant. Fibractiv 105 mg Tablet should be used only if the potential benefit justifies the potential risk.

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Breast Feeding

Unsafe

Fibractiv 105 mg Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Fibractiv 105 mg Tablet .

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Driving

Safe if prescribed

Fibractiv 105 mg Tablet does not impact your ability to drive or operate machinery.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function.

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Kidney

Caution

Fibractiv 105 mg Tablet should not be used in severe kidney problems, including in patients on dialysis. However, mild to moderate kidney patients can use Fibractiv 105 mg Tablet if prescribed by the doctor.

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Children

Caution

Fibractiv 105 mg Tablet is not recommended for children under the age of 18.

FAQs

Fibractiv 105 mg Tablet is used to treat raised or increased cholesterol levels or fat/oils.
Fibractiv 105 mg Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).
You should not take Fibractiv 105 mg Tablet if you are allergic to fibric acid derivative or Fibractiv 105 mg Tablet , have a severe renal impairment (including dialysis patient), have active liver disease, gallbladder disease (gallstone) or are a nursing mother.
Increased liver enzymes (like liver function tests - LFTs), rhinitis, stuffy/runny nose, nausea, indigestion, headache and back pain are some common side effects that may occur in some cases.
No, Fibractiv 105 mg Tablet does not reduce the risk of having heart problems in patients with type 2 diabetes.
Long-term complications of Fibractiv 105 mg Tablet are muscle problems (like unexplained muscle pain) and liver problems (with increased liver enzymes). So, if you experience these symptoms, please consult a doctor.
Fibractiv 105 mg Tablet raises the risk of muscle pain and a serious muscle problem called rhabdomyolysis. The risk is higher if you take the drug along with statins.
It is completely fine to use oral contraceptives with Fibractiv 105 mg Tablet as no such interactions have been found. Consult your doctor for further advice.
If you forget to take a dose of Fibractiv 105 mg Tablet , take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not take more than the prescribed dose of Fibractiv 105 mg Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Avoid drinking alcohol as Fibractiv 105 mg Tablet can raise liver enzymes, thereby damaging your liver.
Periodic monitoring of red and white blood cell counts is recommended during the first 12 months of Fibractiv 105 mg Tablet administration.
Fibractiv 105 mg Tablet may cause liver damage and inflammation after years of use.

Country of origin

India

Manufacturer/Marketer address

no.3/10, mmtc colony, nanganallur, chennai - 600061
Other Info - FIB0068

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