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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:40 PM IST
Fiboxo-40 Tablet is used to prevent severe gout attacks or flares. It contains Febuxostat, which reduces the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. It may cause common side effects such as nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Composition

FEBUXOSTAT-40MG

Manufacturer/Marketer

Rejuva Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Fiboxo-40 Tablet

Fiboxo-40 Tablet belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used to prevent severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. Fiboxo-40 Tablet prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

Fiboxo-40 Tablet contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Fiboxo-40 Tablet is used to prevent gout attacks or flares.

Your doctor will advise you on how often you take off the Fiboxo-40 Tablet based on your medical condition. The common side effects of Fiboxo-40 Tablet nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Most of these side effects of Fiboxo-40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking a Fiboxo-40 Tablet of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to Fiboxo-40 Tablet or any other medicines, have a heart problem (Fiboxo-40 Tablet may cause heart problems that can lead to heart attack), or have kidney/liver disease. Some people experience more gout flare-ups when you start taking Fiboxo-40 Tablet . You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start Fiboxo-40 Tablet . The safety and effectiveness of children under 18 years of age have not been established, so Fiboxo-40 Tablet should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Fiboxo-40 Tablet .

Uses of Fiboxo-40 Tablet

Treatment of severe gout, prevention of gout attacks.

Medicinal Benefits

Fiboxo-40 Tablet is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Fiboxo-40 Tablet is used to prevent gout attacks or flares.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fiboxo-40 Tablet

  • Nausea
  • Rash
  • Dizziness
  • Diarrhoea
  • Joint pain
  • Rash,
  • Inaccurate liver function test results
  • Gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night)
  • Localized swelling due to retention of fluids in tissues (oedema)

Drug Warnings

You should avoid taking Fiboxo-40 Tablet if you are allergic to Fiboxo-40 Tablet , or have heart-related problems, as it increases the risk of a heart attack. It should be used cautiously in patients with kidney problems and blood disorders. Caution is required before taking Fiboxo-40 Tablet if you are pregnant, planning to become pregnant, or already a breastfeeding mother. The safety and effectiveness of children under 18 years of age have not been established, so Fiboxo-40 Tablet should not be given to them.

Drug Interactions

Drug-Drug Interactions: Fiboxo-40 Tablet interacts with anticancer medications (mercaptopurine, methotrexate), immunosuppressant medications (azathioprine), antidiabetic medications (rosiglitazone), and antiasthma medications (theophylline).

Drug-Food Interactions: Intake of alcohol may increase the risk of side effects, so avoid taking alcohol with Fiboxo-40 Tablet . Limit the purine-rich diet.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines,  hyperuricemia (an abnormally high level of uric acid in the blood), heart diseases, liver or kidney diseases before taking Fiboxo-40 Tablet .

Drug-Drug Interactions Checker List

  • MERCAPTOPURINE
  • METHOTREXATE
  • AZATHIOPRINE
  • THEOPHYLLINE
  • ROSIGLITAZONE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish can help in reducing inflammation in the tissue.

  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic movements like walking on a treadmill and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Avoid a high purine-rich diet, including organ meats (kidneys, liver, and sweetbreads) and oily fish (sardines, anchovies, and herring).
  • Limit meat in favour of plant-based proteins like beans and legumes.
  • Eat complex carbohydrates, such as whole-grain bread, fruits, and vegetables, rather than sugary sweets and refined carbohydrates like white bread.
  • Avoid drinking beer and alcoholic beverages and drink plenty of water or other nonalcoholic beverages.

Special Advise

  • Please consult your doctor and check your levels of uric acid two weeks after starting Fiboxo-40 Tablet . Your goal is a uric acid level in your blood that is less than 6 mg/dL.

Disease/Condition Glossary

Gout: Gout is a type of arthritis called 'gouty arthritis'. It is caused by a build-up of a naturally occurring chemical (uric acid) in your body (hyperuricemia). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation. The general signs and symptoms of gout include sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, mostly in the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain, often waking you up in the middle of the night with the sensation that your big toe is on fire.

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Alcohol

Caution

You should avoid taking alcohol while taking Fiboxo-40 Tablet because alcohol may affect Fiboxo-40 Tablet effectiveness.

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Pregnancy

Caution

Fiboxo-40 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

There is limited data on how Fiboxo-40 Tablet affects breastfeeding. Please consult your doctor before starting Fiboxo-40 Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience sleepiness, blurred vision and numbness or tingling sensation while using Fiboxo-40 Tablet . Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and any potential risks before prescribing Fiboxo-40 Tablet .

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Kidney

Caution

Fiboxo-40 Tablet should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.

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Children

Caution

Fiboxo-40 Tablet is not recommended for children below the age of 18 years. The safety and efficacy of Fiboxo-40 Tablet have not been established in children due to limited testing of this drug on children.

Country of origin

India

Manufacturer/Marketer address

516, 3rd Floor, Deep Plaza Complex, Gurgaon Distt. Court Civil Lines, Gurgaon, Haryana
Other Info - FIB0089

Author Details

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FAQs

Fiboxo-40 Tablet is used to prevent severe gout attacks or flares. It prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.
Fiboxo-40 Tablet is a class of antigout drugs called xanthine oxidase inhibitors. It works by decreasing a high amount of uric acid to the normal level that is made in the body. Fiboxo-40 Tablet is used to prevent gout attacks but not to treat them once they occur.
No, Do not discontinue Fiboxo-40 Tablet without consulting your doctor. To treat your condition effectively, continue taking Fiboxo-40 Tablet for as long as prescribed. If you stop taking Fiboxo-40 Tablet , your uric acid levels will likely remain high and continue to cause gout symptoms.
Fiboxo-40 Tablet is not recommended if you have heart disease; taking Fiboxo-40 Tablet may cause serious heart problems, which can be life-threatening in some cases. So, please consult your doctor before taking the Fiboxo-40 Tablet .
Do not drive or operate machinery if you experience dizziness or drowsiness while using Fiboxo-40 Tablet .
The dose and duration of Fiboxo-40 Tablet depend upon your medical condition. It may take several months before Fiboxo-40 Tablet begins to prevent gout attacks. Do not stop taking Fiboxo-40 Tablet without the advice of your doctor even if you feel better.
It is best taken in the morning. You can take Fiboxo-40 Tablet with or without food. Keep taking Fiboxo-40 Tablet every day, to prevent gout attacks.
Chronic hyperuricemia is a condition in which serum uric acid levels are higher than normal.
Hyperuricemia occurs when the body produces too much uric acid or when the kidneys are unable to excrete it properly.
Side effects of Fiboxo-40 Tablet include nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localised swelling due to retention of fluids in tissues (oedema). Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Fiboxo-40 Tablet may cause frequent urination, kidney stones, blood in urine, reduced ability to function properly, and abnormal urine tests. Talk to the doctor if you have any concerns.
You should know that Fiboxo-40 Tablet may cause gout flares, cardiovascular events, and liver problems. Inform the doctor if you have kidney or liver problems, a history of heart disease or stroke, or if you are pregnant/breastfeeding.
Fiboxo-40 Tablet may cause liver failure and liver function abnormalities. Consult the doctor if you notice signs of liver injury such as fatigue, right upper abdominal discomfort, jaundice, dark urine, or anorexia.

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