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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Febrex Plus Tablet is a respiratory medicine mainly used to treat the common cold and allergies. This combination medicine works by blocking the action of histamine and thereby helps reduce symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It may cause common side effects like drowsiness, sleepiness, nausea, fatigue, difficulty sleeping, and headache.

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Manufacturer/Marketer :

Indoco Remedies Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Febrex Plus Tablet

Febrex Plus Tablet belongs to the class of medication called 'cough and cold medications' primarily used to treat common cold symptoms and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth, or eyes and spreads quickly through droplets in the air when the person who is sick sneezes, coughs, or talks.

Febrex Plus Tablet is a combination of three drugs: Paracetamol (mild analgesic and antipyretic), Phenylephrine hydrochloride (decongestant), and Chlorpheniramine maleate (antihistamine/antiallergic). Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Phenylephrine hydrochloride works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy.

Take Febrex Plus Tablet as prescribed. Your doctor will recommend how often you must take Febrex Plus Tablet based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty falling or staying asleep), blurred vision, constipation, and dry mouth. Most of these side effects of Febrex Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Febrex Plus Tablet or any other medicines. If you are pregnant, it is advised to inform your doctor before using Febrex Plus Tablet . Do not use Febrex Plus Tablet if you are breastfeeding without a doctor’s advice, as it may be excreted in breast milk and cause harm to the baby. Febrex Plus Tablet is not recommended for children below four years. Please do not take more than the prescribed dose of Febrex Plus Tablet as it may cause liver damage.

Uses of Febrex Plus Tablet

Treatment of Common cold and Allergies

Directions for Use

Take it with or without food as advised by the doctor. Swallow it whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Febrex Plus Tablet contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

How Febrex Plus Tablet Works

Febrex Plus Tablet is a combination of three drugs: Paracetamol (mild analgesic and antipyretic), Phenylephrine hydrochloride (decongestant), and Chlorpheniramine maleate (antihistamine/antiallergic). Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Phenylephrine hydrochloride works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Febrex Plus Tablet

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Constipation
  • Dry mouth

What if I have taken an overdose of Febrex Plus Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, loss of appetite, stomach pain, confusion, weakness or sweating. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Febrex Plus Tablet or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Febrex Plus Tablet . Do not use Febrex Plus Tablet if you are breastfeeding without a doctor’s advice, as it may be excreted in breast milk and cause harm to the baby. Febrex Plus Tablet is not recommended for children below 4 years. Please do not take more than the prescribed dose of Febrex Plus Tablet as it may cause liver damage.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Febrex Plus Tablet .

Drug-Drug Interactions

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PhenylephrineFurazolidone
Critical
PhenylephrinePropofol
Critical

Drug-Drug Interactions

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PhenylephrineFurazolidone
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Taking Furazolidone with Febrex Plus Tablet 15's can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Febrex Plus Tablet 15's is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Febrex Plus Tablet 15's only after 14 days of stopping Furazolidone.
PhenylephrinePropofol
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Taking Febrex Plus Tablet 15's with Propofol may lead to increased levels of Febrex Plus Tablet 15's leading to side effects like high blood pressure.

How to manage the interaction:
Taking Febrex Plus Tablet 15's with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Co-administration of Febrex Plus Tablet 15's with Sevoflurane can increase the levels of Febrex Plus Tablet 15's and lead to side effects.

How to manage the interaction:
Taking Febrex Plus Tablet 15's with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Taking Tranylcypromine with Febrex Plus Tablet 15's can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Febrex Plus Tablet 15's is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Co-administration of Selegiline with Febrex Plus Tablet 15's together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Febrex Plus Tablet 15's is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Taking Febrex Plus Tablet 15's and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Febrex Plus Tablet 15's with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Febrex Plus Tablet 15's:
Taking Febrex Plus Tablet 15's and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Febrex Plus Tablet 15's with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Febrex Plus Tablet 15's:
Co-administration of ketamine and Febrex Plus Tablet 15's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Febrex Plus Tablet 15's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Febrex Plus Tablet 15's:
Co-administration of Febrex Plus Tablet 15's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Febrex Plus Tablet 15's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Febrex Plus Tablet 15's:
Co-administration of Mipomersen with Febrex Plus Tablet 15's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Febrex Plus Tablet 15's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid consumption of alcohol with Febrex Plus Tablet as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Febrex Plus Tablet Substitute

Substitutes safety advice
  • Flucold Tablet 10's

    4.37per tablet
  • Medler New Tablet 10's

    4.91per tablet
  • Zincold Tablet 15's

    5.58per tablet
  • Sinarest New Tablet 10's

    5.00per tablet
  • Cosome MSR Tablet 10's

    4.46per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Febrex Plus Tablet as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Febrex Plus Tablet .

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Pregnancy

Caution

The safety of Febrex Plus Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Febrex Plus Tablet may be excreted in breast milk and harm the baby. It may also slow milk production, so it is better to contact a doctor before a lactating mother takes it.

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Driving

Caution

Febrex Plus Tablet may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Febrex Plus Tablet .

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Liver

Caution

Take Febrex Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose as required.

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Kidney

Caution

Take Febrex Plus Tablet with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Febrex Plus Tablet is not recommended for children below four years of age. However, please consult a doctor before giving Febrex Plus Tablet to children.

FAQs

Febrex Plus Tablet is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
Febrex Plus Tablet contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Thereby providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Febrex Plus Tablet contains paracetamol, which acts as a mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.
Febrex Plus Tablet may cause drowsiness. It is not necessary for everyone taking Febrex Plus Tablet to experience this side effect. Therefore, avoid driving or operating heavy machinery if you feel drowsy after taking Febrex Plus Tablet .
It is not recommended to take Febrex Plus Tablet with Cetirizine, as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness, and difficulty concentrating. However, please consult a doctor before taking Febrex Plus Tablet with other medicines.
You are not recommended to stop taking Febrex Plus Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Febrex Plus Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Febrex Plus Tablet , please consult your doctor.
Do not use Febrex Plus Tablet if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Febrex Plus Tablet if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Febrex Plus Tablet may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, stop taking Febrex Plus Tablet and contact your doctor.
No, Febrex Plus Tablet contains a decongestant ingredient called Phenylephrine hydrochloride, which may raise blood pressure, especially in people who already have high blood pressure (hypertension). If your blood pressure stays high after taking Febrex Plus Tablet , please consult your doctor.
You should take Febrex Plus Tablet at the recommended dose and duration or as prescribed by your doctor.
No, Febrex Plus Tablet may be excreted in breast milk and could harm the baby. It may also reduce milk production. Therefore, it is best to consult a doctor before a lactating mother takes it.
Yes, Febrex Plus Tablet contains a decongestant and an antihistamine, which can help relieve the symptoms of a blocked nose. The decongestant works to reduce nasal congestion, and the antihistamine helps with any allergy symptoms you may have. However, please consult your doctor before using Febrex Plus Tablet to ensure it is right for you.
No, do not take Febrex Plus Tablet for more than seven days in a row (for adults) or five days (for children over 4) without consulting your doctor. Using Febrex Plus Tablet for a longer time may cause side effects.
Febrex Plus Tablet is a medication commonly used to relieve symptoms of a cough and cold. However, it does not directly target the cough itself. It may help with some associated symptoms, such as sneezing, runny or stuffy nose, fever, headache, body pains, congestion, or watery eyes. Please consult your doctor for the medications effective for managing a cough.
Febrex Plus Tablet is composed of Chlorpheniramine maleate, Paracetamol, and Phenylephrine hydrochloride, which are primarily used to treat common cold symptoms, allergies, and fever.
Febrex Plus Tablet is not an antibiotic. It contains a combination of a decongestant, antihistamine, and antipyretic. It does not target bacterial infections like an antibiotic would.
Febrex Plus Tablet is generally safe when used as directed by your doctor, especially for short-term use in people with common cold symptoms and allergies. However, you should inform your doctor if you have high blood pressure, diabetes, glaucoma, overactive thyroid (hyperthyroidism), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), an enlarged prostate, or any kidney, liver, heart, or urinary problems, before using Febrex Plus Tablet .
Febrex Plus Tablet may potentially harm your liver if taken in excessive doses or for a long time, especially if you have pre-existing liver problems. Please consult your doctor before using Febrex Plus Tablet , as your doctor may adjust the dosage if necessary.
Febrex Plus Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.

Country of origin

India

Manufacturer/Marketer address

Indoco Remedies Limited, Indoco House, 166 Cst Road, Santacruz (E), Mumbai 400 098, India
Other Info - FEB0249

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