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  3. Ezepnem 1Gm Inj

Ezepnem 1Gm Inj, Pack of 1 Injection
Ezepnem 1Gm Inj, Pack of 1 Injection
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Ezepnem 1Gm Inj is an antibiotic used to treat bacterial infections. It can be used to treat intra-abdominal (stomach) infections, skin infections such as diabetic foot infections, community-acquired pneumonia (lung infection), and acute (short-term) gynaecological infections such as urinary tract infections and pelvic infections. It is also used to prevent surgical site infections in patients who have undergone surgery on the colon or rectum.
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Composition :

ERTAPENEM-1GM

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ezepnem 1Gm Inj

Ezepnem 1Gm Inj belongs to a class of medications called ‘antibiotics’ used to treat bacterial infections. It can be used to treat intra-abdominal (stomach) infections, skin infections such as diabetic foot infections, community-acquired pneumonia (lung infection), and acute (short-term) gynaecological infections such as urinary tract infections and pelvic infections. It is also used to prevent surgical site infections in patients who have undergone surgery on the colon or rectum.

Ezepnem 1Gm Inj contains ‘Ertapenem’, which belongs to the class of ‘carbapenem antibiotics. It has bactericidal action and kills the bacteria that are causing the infection. It works by destroying the cell wall (outer layer of the bacteria), which is essential for its survival. Ezepnem 1Gm Inj does not work against infections caused by viruses.

Ezepnem 1Gm Inj is available in the form of injection and infusion. You should take this medicine exactly as prescribed by your doctor. The common side-effects of Ezepnem 1Gm Inj are nausea, vomiting, diarrhoea, headache, and injection site pain. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.

Do not take Ezepnem 1Gm Inj if you are allergic to ‘Ertapenem’ or antibiotics such as penicillins, cephalosporins, and carbapenems. Before taking Ezepnem 1Gm Inj, inform your doctor if you have diarrhoea, brain disorders such as seizures (fits), have been taking valproic acid medicine for treating seizures, have kidney failure, and be on a controlled sodium diet. Also, inform your doctor if you are pregnant or breastfeeding. Do not use Ezepnem 1Gm Inj in children below 2 years of age. In the elderly, dosage adjustments may not be necessary except in patients with kidney failure. Ezepnem 1Gm Inj may not interact with alcohol. Ezepnem 1Gm Inj may cause dizziness (less common), so do not drive or operate heavy machinery if you feel dizzy.

Uses of Ezepnem 1Gm Inj

Treatment of Bacterial Infections (Intra-abdominal infections, Diabetic foot infections, Community-acquired pneumonia, Urinary tract infections, Pelvic infections, etc.)

Directions for Use

Ezepnem 1Gm Inj is given by a doctor or a healthcare professional, so do not self-administer. The dose and duration are determined by the doctor based on your health condition.

Medicinal Benefits

Ezepnem 1Gm Inj contains ‘Ertapenem’, which belongs to the class of ‘carbapenem antibiotics. It is used in the treatment of high-risk or serious bacterial infections. Ertapenem has bactericidal action and works by killing the bacteria causing the infection. It interferes with the formation of the cell wall, which is essential for the bacteria's survival. It has a broad spectrum of activity and is active against both gram-positive and gram-negative bacteria. It can act against various bacterial strains, such as Enterobacteriaceae (cause infections in healthcare settings), Streptococcus pneumonia (cause community-acquired pneumonia), and anaerobic bacteria, which are common causes of serious infections.

How Ezepnem 1Gm Inj Works

Ezepnem 1Gm Inj contains ‘Ertapenem’, which belongs to the class of ‘carbapenem antibiotics. It has bactericidal action and kills the bacteria that are causing the infection. It works by destroying the cell wall (outer layer of the bacteria), which is essential for its survival.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ezepnem 1Gm Inj
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Ezepnem 1Gm Inj

The overdose of Ezepnem 1Gm Inj is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Ezepnem 1Gm Inj, please inform your doctor immediately.

Drug Warnings

Do not take Ezepnem 1Gm Inj for prolonged periods as long-term use may cause superinfection (additional infection caused by other microbes). Ezepnem 1Gm Inj should not be used in patients with diabetic foot infections with ‘osteomyelitis’ (an infection of the bone) as there is no much research regarding the safe use of Ezepnem 1Gm Inj in these populations. Ezepnem 1Gm Inj should be used with caution in patients with brain disorders such as seizures (fits) as it may worsen the condition. If you experience diarrhoea before, during, or after the treatment, do not take self-medication without discussing it with your doctor.  Diarrhoea may also occur due to the inflammation of the colon. Ezepnem 1Gm Inj contains sodium, so it should be used with caution in patients on a sodium-restricted diet. Ezepnem 1Gm Inj may also cause a change in liver function tests, a change in platelet count, and a change in white blood cell count (in children). So, it is essential to monitor these tests if you are taking this medicine frequently.

Drug-Drug Interactions

verifiedApollotooltip
ErtapenemDivalproex
Severe
ErtapenemIomeprol
Severe

Drug-Drug Interactions

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ErtapenemDivalproex
Severe
How does the drug interact with Ezepnem 1Gm Inj:
Coadministration of Ezepnem 1Gm Inj with Divalproex may reduce the blood levels of Divalproex and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, Ezepnem 1Gm Inj can be taken with Divalproex if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
ErtapenemIomeprol
Severe
How does the drug interact with Ezepnem 1Gm Inj:
Co-administration of Iomeprol and Ezepnem 1Gm Inj may increase the risk or severity of seizures.

How to manage the interaction:
Co-administration of Ezepnem 1Gm Inj and Iomeprol can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ErtapenemBCG vaccine
Severe
How does the drug interact with Ezepnem 1Gm Inj:
When BCG vaccine is used with Ezepnem 1Gm Inj, its effectiveness may be reduced.

How to manage the interaction:
Although there is a possible interaction between Ezepnem 1Gm Inj and BCG vaccine, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
ErtapenemTramadol
Severe
How does the drug interact with Ezepnem 1Gm Inj:
The combined use of tramadol with Ezepnem 1Gm Inj can make tramadol less effective as a treatment.

How to manage the interaction:
Taking Ezepnem 1Gm Inj with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ErtapenemBupropion
Severe
How does the drug interact with Ezepnem 1Gm Inj:
Co-administration of Bupropion may rarely cause seizures and combining it with Ezepnem 1Gm Inj may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Ezepnem 1Gm Inj can be taken with bupropion if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
ErtapenemMetrizamide
Severe
How does the drug interact with Ezepnem 1Gm Inj:
Co-administration of Metrizamide and Ezepnem 1Gm Inj may increase the risk or severity of seizures.

How to manage the interaction:
Co-administration of Ezepnem 1Gm Inj and Metrizamide can lead to an interaction, it can be taken if advised by a doctor. However, if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ErtapenemSodium Valproate
Severe
How does the drug interact with Ezepnem 1Gm Inj:
The combined use of Ezepnem 1Gm Inj and sodium valproate can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ezepnem 1Gm Inj and sodium valproate can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat healthily. Opt for a balanced and nutrient-rich diet. 
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder antibiotic absorption.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Ezepnem 1Gm Inj Substitute

Substitutes safety advice

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Product Substitutes

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Alcohol

Caution

Ezepnem 1Gm Inj may not interact with alcohol. However, it is advised not to consume alcohol as it may interfere with your ability to fight infections.

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Pregnancy

Caution

Ezepnem 1Gm Inj is a category B medicine and may not cause harmful effects on the unborn baby. However, your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Ezepnem 1Gm Inj may get secreted in the breast milk. Your doctor may advise you to stop breastfeeding while using this medicine.

bannner image

Driving

Caution

Ezepnem 1Gm Inj may cause dizziness in some cases. So, do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Safe if prescribed

Ezepnem 1Gm Inj is probably safe when used in patients with liver diseases. However, if you have liver problems, inform your doctor before taking this medicine.

bannner image

Kidney

Caution

Ezepnem 1Gm Inj should be used with caution if you have kidney problems. Your doctor may adjust the dose if necessary based on your condition.

bannner image

Children

Caution

Ezepnem 1Gm Inj is not recommended for use in children below 2 years of age. Your doctor will decide the dose of Ezepnem 1Gm Inj based on your child's age and condition.

Have a query?

FAQs

Ezepnem 1Gm Inj is used to treat bacterial infections. It can be used to treat intra-abdominal (stomach) infections, skin infections such as diabetic foot infections, community-acquired pneumonia (lung infection), and acute (short-term) gynaecological infections such as urinary tract infections and pelvic infections. It is also used to prevent surgical site infections in patients who have undergone surgery on the colon or rectum.

Ezepnem 1Gm Inj contains ‘Ertapenem’, which belongs to the class of ‘carbapenem antibiotics. It has bactericidal action and kills the bacteria that are causing the infection. It works by destroying the cell wall (outer layer of the bacteria), which is essential for its survival.

Ezepnem 1Gm Inj may not cause anemia. However, it can lower platelet and white blood cell (WBC) count in some patients. Consult your doctor immediately.

Ezepnem 1Gm Inj may cause side effects such as nausea, vomiting, diarrhea, headache, and injection site pain. These side effects are usually mild and temporary. However, if any of these side effects persist or get severe, consult a doctor immediately.

Ezepnem 1Gm Inj is used only to treat community-acquired pneumonia. However, it is not used in patients with community-acquired pneumonia associated with osteomyelitis (a bone infection). So, you must inform your doctor about all the symptoms and illnesses you have before using Ezepnem 1Gm Inj.

intra-abdominal infection is a broader term used to describe infections associated with the stomach, intestine, peritoneum (lining of the abdominal wall), or other parts present in the abdomen. It mostly occurs due to a complication of another condition, such as appendicitis, following surgery, or a trauma. Common symptoms include nausea, vomiting, abdominal pain, and change in bowel habits.Â

If Ezepnem 1Gm Inj isn't suitable for you, don't hesitate to share any concerns or issues with Ezepnem 1Gm Inj, and your doctor will guide you through the next steps. They will explore alternative treatments. They may recommend a different antibiotic or adjust the dosage to minimize side effects. Your doctor will work closely with you to find a personalized solution for your unique needs and medical history.

Drug resistance occurs when bacteria or other microbes adapt and stop reacting to the medications intended to kill them. This makes infections more difficult to treat. Yes, it is possible to become resistant to Ezepnem 1Gm Inj. Bacteria can create enzymes called carbapenemases that break down Ezepnem 1Gm Inj, rendering it useless.

Ezepnem 1Gm Inj may cause a drop in blood sugar levels, although this is not very common. If you have diabetes and are prescribed Ezepnem 1Gm Inj to treat foot infections, regular blood sugar monitoring is crucial. Consult your doctor if you notice significant changes.

Ezepnem 1Gm Inj is not recommended for use in children below 2 years of age. Your doctor will decide the dose of Ezepnem 1Gm Inj based on your child's age and condition.

Do not stop taking your Ezepnem 1Gm Inj even if you are feeling better! It's important to have a complete recovery. Stopping too soon can cause incomplete recovery, recurrence of symptoms, and side effects. Instead, tell your doctor about your development and follow their instructions to ensure the best outcome for your health.

Country of origin

INDIA

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - EZE0025

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.ema.europa.eu/en/documents/product-information/invanz-epar-product-information_en.pdf
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