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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Extacef-Plus Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea. It contains Cefixime and Ofloxacin, which works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. It prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. It may cause some common side effects such as diarrhoea, indigestion, nausea, loose stools, abdominal pain, and vomiting.
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Prescription drug

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Manufacturer/Marketer :

Blue Cross Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Extacef-Plus Tablet belongs to a group of medications called 'cephalosporin antibiotics' primarily used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea. A bacterial infection happens when harmful bacteria enter inside the body and start multiplying. These harmful bacteria are responsible for producing toxins that can cause diseases like strep throat, urinary tract infection (UTI), bacterial food poisoning, gonorrhoea, bacterial meningitis, cellulitis, Lyme disease, and tetanus. Extacef-Plus Tablet does not work against viral infections like flu and colds.

Extacef-Plus Tablet contains 'Cefixime' (cephalosporin antibiotic) and 'Ofloxacin' (fluoroquinolone antibiotic) that works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. Extacef-Plus Tablet prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. Extacef-Plus Tablet is a broad range antibiotic that works against a wide range of both gram-positive and gram-negative bacteria.

Take Extacef-Plus Tablet as prescribed. Your doctor will recommend how often you take Extacef-Plus Tablet based on your medical condition. Extacef-Plus Tablet may cause some common side effects that include diarrhoea, indigestion, nausea, loose stools, abdominal pain, and vomiting. However, some of these side effects do not require medical attention and will pass within a couple of days. If side effects become get worse with time or do not pass within a couple of days, then one should consult their doctor. 

Extacef-Plus Tablet is not allowed to use in patients who are already taking any of the other antibiotics or having kidney or liver problems. This medicine can only be used in pregnant or breastfeeding women if strongly suggested by the doctor. Ofloxacin present in Extacef-Plus Tablet may cause and aggravate symptoms of existing peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), and respiratory issues like bronchitis, sinusitis. People with diabetes should contact a doctor before taking Extacef-Plus Tablet as Extacef-Plus Tablet can lower your blood sugar level in some cases. Patient with central nervous system disorder or epilepsy (fits) should avoid intake of Extacef-Plus Tablet as its use is contraindicated for them.

Treatment of Bacterial infections, Typhoid fever, Urinary tract infection (UTI)
Tablet: Take it with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Tablet DT: Take it with food as advised by the doctor. Disperse the tablet in a spoonful (15ml) of boiled and cooled water. Consume immediately.

Extacef-Plus Tablet is a combination of cephalosporin and fluoroquinolone antibiotics that works by killing the bacteria (bactericidal). Cefixime works by stopping the growth of bacteria by inhibiting the formation of a protective layer required by the bacteria or its growth. At the same time, Ofloxacin acts by blocking the action of a chemical messenger, which helps the genetic material of bacteria to survive. The doctor usually prescribes Extacef-Plus Tablet for the treatment of typhoid fever and urinary tract infections. Besides this, it also treats bacterial infections of the prostate, skin, lungs, sexually transmitted infections like gonorrhoea (cervical/urethral), ear infections (acute otitis media), upper respiratory tract infections (URTI), lower respiratory tract infection, tonsillitis (inflammation of the tonsils) and pharyngitis (inflammation of the pharynx). 

Extacef-Plus Tablet contains 'Cefixime' (cephalosporin antibiotic) and 'Ofloxacin' (fluoroquinolone antibiotic) that works by preventing the formation of the outer covering of the bacteria (cell wall) required for their survival. Extacef-Plus Tablet prevents the release of a chemical messenger (mucopeptides) by the bacteria, thereby weakening and destroying the bacterial cell wall. Extacef-Plus Tablet is a broad range antibiotic that works against a wide range of both gram-positive and gram-negative bacteria.
Store in a cool and dry place away from sunlight
  • Diarrhoea
  • Nausea
  • Dyspepsia (Indigestion)
  • Loose stools
  • Abdominal pain
  • Vomiting
Do not take more than the prescribed dose of Extacef-Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

You should avoid taking Extacef-Plus Tablet if you are hypersensitive to ofloxacin, cefixime or other macrolide antibiotics as it may lead to overdose and toxicity. The use of Extacef-Plus Tablet is only allowed in pregnancy or breastfeeding if clearly suggested by the doctor. Tell your doctor if you are pregnant, or breastfeeding before using Extacef-Plus Tablet . Ofloxacin present in Extacef-Plus Tablet may cause and aggravate symptoms of existing peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), and respiratory issues like bronchitis, sinusitis. People with diabetes should contact a doctor before taking Extacef-Plus Tablet as Extacef-Plus Tablet can lower your blood sugar level in some cases. Patient with central nervous system disorder or epilepsy (fits) should avoid intake of Extacef-Plus Tablet as its use is contraindicated for them. 

verifiedApollotooltip
OfloxacinAmiodarone
Critical
OfloxacinHalofantrine
Critical

Drug-Drug Interactions

OfloxacinAmiodarone
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
The combination of Amiodarone and Extacef-Plus Tablet 10's may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Extacef-Plus Tablet 10's interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Using halofantrine together with Extacef-Plus Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinThioridazine
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinCisapride
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinZiprasidone
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Using bepridil together with Extacef-Plus Tablet 10's drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Using Mesoridazine together with Extacef-Plus Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Extacef-Plus Tablet 10's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinSotalol
Critical
How does the drug interact with Extacef-Plus Tablet 10's:
Coadministration of Extacef-Plus Tablet 10's with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Extacef-Plus Tablet 10's with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Include probiotics in your diet as probiotics contain healthy bacteria that are good for the intestines and can recover the killed bacteria.
  • Taking probiotics after completing the antibiotics course can minimize the chances of antibiotic-associated diarrhoea. Foods that are high in probiotics include yoghurt, cheese, sauerkraut, and kimchi so consume them to restore the good bacteria of the intestine. 
  • Try to take more fibre-enriched food as it will help the food to digest properly and helps to stimulate the growth of gut bacteria.
  • Include whole grains like whole-grain bread, brown rice to include fibre in your diet.
  • Try to consume less calcium, iron-enriched foods, and drinks as it may slow down the working of Extacef-Plus Tablet . 
  • Try to limit the consumption of alcoholic beverages as it can cause worsening of side effects and make your body dehydrated and affect your sleep. This also makes it difficult for your body to aid the Extacef-Plus Tablet in fighting off infections.
No
ANTI- BACTERIALS

Extacef-Plus Tablet Substitute

Substitutes safety advice
  • Taxim-OF Tablet 10's

    17.28per tablet
  • Zifi-O Tablet 10's

    18.18per tablet
  • Mahacef-Plus Tablet 10's

    15.80per tablet
  • Zanocin Plus Tablet 10's

    16.65per tablet
  • Cefix O Tablet 10's

    by AYUR

    26.33per tablet
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FAQs

Extacef-Plus Tablet is used for the treatment of a wide range of bacterial infections of the skin, ears, lungs, prostate and urinary tract. Besides this, it also treats typhoid fever and STDs (sexually transmitted diseases) like chlamydia and gonorrhoea.
No, you should not double the dose if you forget to take Extacef-Plus Tablet , then take it as soon as you remember or skip it if it's time for the next dose.
Yes, some patients may experience diarrhoea, after taking this medicine so it is better to take this drug after a meal which reduces the risk of stomach discomfort. However, If you are noticing diarrhoea that is watery or bloody, then immediately ask your doctor. Do not try to take self-medication for diarrhoea without asking the doctor.
Yes, this medicine is prescribed for the treatment of urinary tract infection (UTI). Take Extacef-Plus Tablet only if the doctor has prescribed you this medicine.
You should avoid driving as this medicine may cause impaired vision or affect the thinking ability so avoid such a task that needs a clear vision.
You should avoid taking Extacef-Plus Tablet if you have peripheral neuropathy (nerve damage in legs), tendinitis (swelling or tearing of a tendon), myasthenia gravis (skeletal muscle weakness), respiratory issues like bronchitis, sinusitis, diabetes, central nervous system disorder, or epilepsy (fits).
No, Extacef-Plus Tablet is not advised for viral infections, such as the common cold. It is a strong antibiotic used to treat severe bacterial infections.
You are advised to take Extacef-Plus Tablet as recommended by your doctor. Complete the full treatment as prescribed to show its effectiveness, as discontinuing suddenly may cause antibiotic resistance.
No, Extacef-Plus Tablet is not recommended for viral infections. Extacef-Plus Tablet is an antibiotic used to treat bacterial infections. Do not self-medicate.
Extacef-Plus Tablet doesn’t respond against the viral infections such as cough. Therefore, if you have cough, consult your doctor for appropriate medication.
Yes, cefix contains cefixime as its active substance and is an antibiotic used to treat bacterial infections of urinary tract, lungs, throat, airways, tonsils, middle ear, and cervical or urethral regions.
Take Extacef-Plus Tablet as recommended by your doctor. Taking Extacef-Plus Tablet with milk may potentially affect its effectiveness.
No, do not take Extacef-Plus Tablet for stomach infections as it could be due to various reasons. Also, avoid taking Extacef-Plus Tablet for any infection without doctor’s advice.
Yes, Extacef-Plus Tablet is a strong antibiotic that can treat various bacterial infections. Do not self-medicate.
Extacef-Plus Tablet can be used for sinus infections (sinusitis) if caused by bacteria and if it is advised by a doctor. However, please consult a doctor as it varies for everyone based on your health condition.
No, do not take Extacef-Plus Tablet on your own as inappropriate usage of antibiotics may cause failure of the treatment in future.
The dosage of Extacef-Plus Tablet treatment vary based on the specific condition and patient response to the medication. If you do not notice any improvement within 3-4 days of starting the treatment, please consult your doctor. Do not self-medicate.
Extacef-Plus Tablet contains Cefixime (cephalosporin antibiotic) and Ofloxacin (fluoroquinolone antibiotic) as its active substances.
Consult your doctor if you don’t get better after using Extacef-Plus Tablet . Also, inform about the unwanted effects and the symptoms that worsen while using Extacef-Plus Tablet .
UTIs are usually treated with antibiotics. To prevent UTIs, it's important to stay hydrated, urinate after sex, avoid irritating female hygiene products, and wear cotton underwear. For frequent UTIs, doctors may recommend low-dose antibiotics or other preventive options, including probiotics.
Store Extacef-Plus Tablet at room temperature. Protect from light. Keep it out of reach from children. Disposal of Extacef-Plus Tablet is done by following the local guidelines.
India
Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, INDIA.
Other Info - EXT0064

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