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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Evolve Eye Drops 5 ml is used to treat dry eyes. It contains Cyclosporine, which allows tear production by decreasing inflammation/swelling in the eye. Thus, it reduces discomfort and keeps the eyes lubricated. Sometimes, Evolve Eye Drops 5 ml may cause side effects like pain, blurred vision, and redness. The safety and effectiveness of this medication in children under 16 years of age have not been established.
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Whats That

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Synonym :

CYCLOSPORIN

Consume Type :

OPHTHALMIC

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Evolve Eye Drops 5 ml

Evolve Eye Drops 5 ml is used to increase tear production in people with dry eyes, which occurs due to ocular inflammation associated with keratoconjunctivitis sicca (dry eyes).
 
Evolve Eye Drops 5 ml contains Cyclosporine, which allows tear production by decreasing inflammation/swelling in the eye. Thus, it reduces discomfort and keeps the eyes lubricated. 
 
In some cases, Evolve Eye Drops 5 ml may cause side effects like pain, blurred vision, and redness of the eye. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of Evolve Eye Drops 5 ml in children below 16 years have not been established. Avoid touching the tip of the container as it may contaminate the contents. Let your doctor know if you are taking any prescription, non-prescription drugs or herbal products.

Uses of Evolve Eye Drops 5 ml

Treatment of Dry eyes

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Medicinal Benefits

Evolve Eye Drops 5 ml belongs to a group of medicines called immunomodulators used to increase tear production in people with dry eyes, which occurs due to ocular inflammation associated with keratoconjunctivitis sicca (dry eyes). Evolve Eye Drops 5 ml contains Cyclosporine, which allows tear production by decreasing inflammation/swelling in the eye. Thus, it reduces discomfort and keeps the eyes lubricated.

How Evolve Eye Drops 5 ml Works

Evolve Eye Drops 5 ml contains Cyclosporine, which allows tear production by decreasing inflammation/swelling in the eye. Thus, it reduces discomfort and keeps the eyes lubricated.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Evolve Eye Drops 5 ml

  • Pain
  • Blurred vision
  • Redness of the eye
  • Itching in the eye
  • Swelling of the eyelid

What if I have taken an overdose of Evolve Eye Drops 5 ml

Overdosing is unlikely harmful, although it is best not to exceed the prescribed amount. Seek emergency medical attention or call your doctor if you notice any unusual symptoms, or anyone has accidentally swallowed the medication or if you suspect that you may have overdosed of Evolve Eye Drops 5 ml.

Drug Warnings

Do not use Evolve Eye Drops 5 ml if you are allergic to any of its components. Inform your doctor if you have/had an eye infection or eye injury. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of Evolve Eye Drops 5 ml in children below 16 years have not been established. Inform your doctor regarding other prescription, non-prescription or herbal medicines you are taking to prevent any side effects/interactions.

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
How does the drug interact with Evolve Eye Drops 5 ml:
Combining Evolve Eye Drops 5 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Evolve Eye Drops 5 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Evolve Eye Drops 5 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Evolve Eye Drops 5 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Evolve Eye Drops 5 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Evolve Eye Drops 5 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Evolve Eye Drops 5 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Evolve Eye Drops 5 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Evolve Eye Drops 5 ml:
Coadministration of pitavastatin with Evolve Eye Drops 5 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Evolve Eye Drops 5 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinFoscarnet
Severe
How does the drug interact with Evolve Eye Drops 5 ml:
Co-administration of foscarnet with Evolve Eye Drops 5 ml may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between foscarnet and Evolve Eye Drops 5 ml, they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinInfliximab
Severe
How does the drug interact with Evolve Eye Drops 5 ml:
When infliximab is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking infliximab and Evolve Eye Drops 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinColchicine
Severe
How does the drug interact with Evolve Eye Drops 5 ml:
Co-administration of colchicine with Evolve Eye Drops 5 ml may increases the blood levels and effects of both medications.

How to manage the interaction:
Although there is a possible interaction between colchicine and Evolve Eye Drops 5 ml, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as abdominal pain, diarrhoea, fever, muscle pain, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
CiclosporinTofacitinib
Severe
How does the drug interact with Evolve Eye Drops 5 ml:
Co-administration of tofacitinib with cyclosporine may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, tofacitinib can be taken with Evolve Eye Drops 5 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without a doctor's advice.
CiclosporinEverolimus
Severe
How does the drug interact with Evolve Eye Drops 5 ml:
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.

How to manage the interaction:
Although taking everolimus and Evolve Eye Drops 5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands regularly. Avoid touching the eyes with dirty hands. 
  • Avoid rubbing the eyes.
  • Avoid sharing eye-makeup such as eyeliner, mascara or kohl.
  • Always use clean towels or tissues to wipe your eyes and face.
  • Regularly wash and change the pillowcases.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands prior to inserting the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
  • Blink regularly as it helps in the spread of hydrating substances such as mucus and tears across the eyes.

Habit Forming

No

Therapeutic Class

OPHTHALMOLOGIC AGENTS

Evolve Eye Drops 5 ml Substitute

Substitutes safety advice
  • Iflo Eye Drop

    52.36per tablet
  • Porin Tears 0.05% Eye Drop

    82.50per tablet
  • Cyclotears Uni-ED Eye Drops 10 x 0.5 ml

    37.00per tablet
  • Cycloaqua Eye Drops 5 ml

    66.00per tablet
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Alcohol

Consult your doctor

It is not known whether alcohol interacts with Evolve Eye Drops 5 ml. However, as a precautionary measure, it is advisable not to consume or limit alcohol.

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Pregnancy

Consult your doctor

If you are pregnant, please consult your doctor before using Evolve Eye Drops 5 ml. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Evolve Eye Drops 5 ml can be used by breastfeeding mothers or not.

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Driving

Caution

Evolve Eye Drops 5 ml may temporarily blur your vision. So, avoid driving or operating machinery until your vision is clear.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns before using Evolve Eye Drops 5 ml.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns before using Evolve Eye Drops 5 ml.

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Children

Caution

Evolve Eye Drops 5 ml is not recommended for use in children below 16 years as the safety and efficacy have not been established.

FAQs

Evolve Eye Drops 5 ml is used to increase tear production in people with dry eyes due to ocular inflammation associated with keratoconjunctivitis sicca (dry eyes).
Evolve Eye Drops 5 ml allows tear production by decreasing inflammation/swelling in the eye. Thereby reducing discomfort and keeping the eyes lubricated.
Evolve Eye Drops 5 ml might temporarily cause blurred vision immediately after use. So, do not drive or operate machinery immediately after using Evolve Eye Drops 5 ml; wait until your vision is clear to prevent any mishappening.
Do not wear contact lenses while using Evolve Eye Drops 5 ml. Remove contact lenses before using Evolve Eye Drops 5 ml and reinsert after 15 minutes of using Evolve Eye Drops 5 ml.
Evolve Eye Drops 5 ml can be used with other eye medications if prescribed by the doctor. Maintain a gap of 15-20 minutes between Evolve Eye Drops 5 ml and other eye medications.
To treat your condition effectually, use Evolve Eye Drops 5 ml for as long as your doctor has prescribed. Talk to your doctor if you experience any difficulty while using Evolve Eye Drops 5 ml.

Country of origin

India

Manufacturer/Marketer address

Arihant Commercial Complex, Building-26 A, Gala No. 3B, Purna Village, Thane Bhiwandi Road, Bhiwandi, Thane, India
Other Info - EVO0060

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