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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
ETOSAFE ER TABLET is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis. It contains Etodolac, which works by reducing the production of a chemical known as prostaglandin, responsible for inducing pain and inflammation in the body. In some cases, you may experience certain common side effects such as stomach pain, diarrhoea, indigestion, headache, loss of appetite, nausea and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ETODOLAC-600MG

Manufacturer/Marketer :

Wanbury Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About ETOSAFE ER TABLET

ETOSAFE ER TABLET is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage.

 

ETOSAFE ER TABLET works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

 

Take ETOSAFE ER TABLET with or after food. You are advised to take ETOSAFE ER TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as stomach pain, diarrhoea, indigestion, headache, loss of appetite, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you should talk to your doctor if you experience these side effects persistently.

 

Consult your doctor before taking ETOSAFE ER TABLET if you are pregnant or breastfeeding; your doctor will prescribe ETOSAFE ER TABLET only if the benefits outweigh the risks. ETOSAFE ER TABLET may cause drowsiness and dizziness, so drive with caution. ETOSAFE ER TABLET is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with ETOSAFE ER TABLET as it could lead to increased drowsiness and dizziness. It could also increase the risk of stomach bleeding.

Uses of ETOSAFE ER TABLET

Treatment of Osteoarthritis, Rheumatoid arthritis

Directions for Use

Take ETOSAFE ER TABLET with or after food. Swallow it as a whole with a glass of water. Do not crush, chew or break the tablet/capsule.

Medicinal Benefits

ETOSAFE ER TABLET works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thus, ETOSAFE ER TABLET helps treat pain associated with osteoarthritis and rheumatoid arthritis.

How ETOSAFE ER TABLET Works

ETOSAFE ER TABLET works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ETOSAFE ER TABLET

  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache
  • Loss of appetite
  • Nausea
  • Vomiting

What if I have taken an overdose of ETOSAFE ER TABLET

Do not take more than the prescribed dose of ETOSAFE ER TABLET as it may cause overdose. The symptoms of overdose include stomach pain, nausea, vomiting, lack of energy, drowsiness, blood/black/tarry stools, vomit that is bloody or looks like coffee grounds or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

ETOSAFE ER TABLET can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not use ETOSAFE ER TABLET. Do not take ETOSAFE ER TABLET if you are allergic to Etodolac, have severe heart failure or peptic ulcer, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking ETOSAFE ER TABLET if you are taking medicines for high blood pressure and fluid retention. Consult your doctor before taking ETOSAFE ER TABLET if you are pregnant or breast-feeding, your doctor will prescribe you ETOSAFE ER TABLET only if the benefits outweigh the risks. ETOSAFE ER TABLET causes drowsiness and dizziness, so drive only if you are alert. ETOSAFE ER TABLET should not be given to children as the safety has not been established. Avoid consuming alcohol along with ETOSAFE ER TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Inform your doctor before taking ETOSAFE ER TABLET if you suffer from fluid retention (swelling), high blood pressure, heart problems, asthma or breathing difficulties. Use of ETOSAFE ER TABLET can make your skin very sensitive to sunlight which can even cause sunburn. So, whenever you step out of home try to apply sunscreen on your skin.

Drug-Drug Interactions

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EtodolacMeloxicam
Critical
EtodolacKetorolac
Critical

Drug-Drug Interactions

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EtodolacMeloxicam
Critical
How does the drug interact with ETOSAFE ER TABLET:
Co-administration of ETOSAFE ER TABLET with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with ETOSAFE ER TABLET is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.
EtodolacKetorolac
Critical
How does the drug interact with ETOSAFE ER TABLET:
Using ketorolac together with ETOSAFE ER TABLET may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking ETOSAFE ER TABLET with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacApixaban
Severe
How does the drug interact with ETOSAFE ER TABLET:
Coadministration of ETOSAFE ER TABLET and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining ETOSAFE ER TABLET and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
EtodolacLeflunomide
Severe
How does the drug interact with ETOSAFE ER TABLET:
Taking ETOSAFE ER TABLET and Leflunomide increase the risk of liver issues.

How to manage the interaction:
Although taking ETOSAFE ER TABLET and Leflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EtodolacPiroxicam
Severe
How does the drug interact with ETOSAFE ER TABLET:
Coadministration of Piroxicam with ETOSAFE ER TABLET can increase the risk of side effects such as inflammation(swelling with redness), bleeding, ulceration.

How to manage the interaction:
Although taking ETOSAFE ER TABLET and Piroxicam together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EtodolacIbrutinib
Severe
How does the drug interact with ETOSAFE ER TABLET:
Co-administration of Ibrutinib with ETOSAFE ER TABLET may increase the risk of bleeding.

How to manage the interaction:
Although taking ETOSAFE ER TABLET and Ibrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, If you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EtodolacCelecoxib
Severe
How does the drug interact with ETOSAFE ER TABLET:
Taking Celecoxib with ETOSAFE ER TABLET can increase the risk of stomach inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is a interaction between ETOSAFE ER TABLET and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
EtodolacDabigatran etexilate
Severe
How does the drug interact with ETOSAFE ER TABLET:
When ETOSAFE ER TABLET is taken with Dabigatran etexilate may increase the risk or severity of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabigatran etexilate with ETOSAFE ER TABLET together can result in an interaction, but it can be taken if a doctor has advised it. However, if you happen to have any unusual bleeding or bruising, or other signs and symptoms of bleeding, such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
EtodolacSirolimus
Severe
How does the drug interact with ETOSAFE ER TABLET:
Coadministration of ETOSAFE ER TABLET and Sirolimus can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and ETOSAFE ER TABLET together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
EtodolacOxaprozin
Severe
How does the drug interact with ETOSAFE ER TABLET:
Taking Oxaprozin with ETOSAFE ER TABLET may raise the risk of gastrointestinal adverse effects (inflammation, bleeding, ulceration, and, in rare cases, perforation).

How to manage the interaction:
Taking ETOSAFE ER TABLET with Oxaprozin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

Habit Forming

No

Therapeutic Class

ANALGESICS

ETOSAFE ER TABLET Substitute

Substitutes safety advice
  • Etova ER 600 Tablet 10's

    23.85per tablet
  • Etogesic-ER Tablet 10's

    23.54per tablet
  • Etoflu ER Tablet 10's

    by AYUR

    18.41per tablet
  • Etolgia-XR 600 mg Tablet 10's

    21.56per tablet
  • Etorite 600 ER Tablet 10's

    by AYUR

    17.19per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking ETOSAFE ER TABLET. Alcohol intake along ETOSAFE ER TABLET may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor before taking ETOSAFE ER TABLET if you are pregnant, your doctor will prescribe you ETOSAFE ER TABLET if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether ETOSAFE ER TABLET passes into the mother’s milk. Please consult your doctor before taking ETOSAFE ER TABLET if you are breast-feeding, your doctor will prescribe you ETOSAFE ER TABLET if the benefits outweigh the risks.

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Driving

Caution

ETOSAFE ER TABLET may cause drowsiness, dizziness or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

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Liver

Caution

Dose adjustment may be needed in patients with severe liver impairment. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with severe kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

ETOSAFE ER TABLET should not be used by children as the efficacy and safety has not been established.

FAQs

ETOSAFE ER TABLET is used to treat mild to moderate pain in osteoarthritis and rheumatoid arthritis.
ETOSAFE ER TABLET works by blocking the effect of chemical messengers (prostaglandin), thereby helping in reducing joint pain, stiffness, swelling and inflammation.
Diarrhoea might be a side-effect of ETOSAFE ER TABLET. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
ETOSAFE ER TABLET might cause stomach-upset, abdominal pain and indigestion. To prevent this take ETOSAFE ER TABLET with or after food.
Do not take ETOSAFE ER TABLET for longer durations or high doses as it may cause heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.
Do not overdose on ETOSAFE ER TABLET or any medicine as it could lead to unpleasant side-effects. Take ETOSAFE ER TABLET only as prescribed by your doctor. Rush to your nearest doctor as early as possible if you have overdosed on ETOSAFE ER TABLET. Symptoms of overdose include nausea, vomiting, stomach pain, headache, blood in stools/faeces.
Yes, ETOSAFE ER TABLET might affect certain test results like blood or urine tests. Inform your doctor that you are taking ETOSAFE ER TABLET before undergoing any tests.
Yes, the use of ETOSAFE ER TABLET can make the skin very sensitive to sunlight which can even cause sunburn. So, whenever you step out of home try to apply sunscreen on your skin.
ETOSAFE ER TABLET can increase your risk of a fatal heart attack or stroke. If you have any recent heart bypass surgery, do not use ETOSAFE ER TABLET.
ETOSAFE ER TABLET may cause side effects such as diarrhoea, stomach pain, indigestion, loss of appetite, headache, nausea and vomiting. If these side effects persist or worsen, please consult your doctor.
Yes, ETOSAFE ER TABLET is a pain-relieving medicine.
ETOSAFE ER TABLET contains Etodolac. It belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
No, ETOSAFE ER TABLET is not a narcotic. It belongs to the class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
No, ETOSAFE ER TABLET does not get you high. It does not lead to physical or psychological dependence and does not have the potential to be abused (drug-seeking behaviour). However, consult your doctor if you are not feeling well.
Patients who are allergic to ETOSAFE ER TABLET or any of its ingredients, should avoid using ETOSAFE ER TABLET. However, if you are using ETOSAFE ER TABLET for the first time or if you are not aware of any allergy, please consult your doctor.
Prolonged use and high doses of ETOSAFE ER TABLET may cause kidney problems, such as blood or protein in urine and pain during urination. Patients with impaired kidney function, heart failure, and hypertension (high blood pressure) are at risk of kidney problems. Patients taking medicines that cause excess urination (diuretics), or medicines which have significant impact on kidney function are also at higher risk of developing kidney problems. Additionally, ETOSAFE ER TABLET can affect kidneys of patients who are over 65 years of age or who remain dehydrated. Thus, monitoring of kidney function is recommended for such patients.
ETOSAFE ER TABLET may cause drowsiness and also dizziness and visual disturbances. However, not everyone taking ETOSAFE ER TABLET will have these effects. If you experience these symptoms, avoid driving or operating heavy machinery.
ETOSAFE ER TABLET is effective if used in the dose and duration prescribed by your doctor. Even if you see improvement in your condition, do not stop using ETOSAFE ER TABLET too early as the symptoms may return or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

Wanbury Limited , BSEL Techpark, 'B' Wing, 10th Floor, Sector 30-A, Opp. Vashi Railway Station, Vashi, Navi Mumbai - 400703, India.
Other Info - ETO0037

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