Etopxel 100 Injection 5 ml belongs to a class of chemotherapy drugs used to treat various cancer conditions, including testicular tumours or cancer of the testicles, lung cancer (small cell lung cancer; SCLC). Besides this, it can also be used in treating Monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Etopxel 100 Injection 5 ml contains Etoposide, which is a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Etopxel 100 Injection 5 ml will be administered by a qualified healthcare professional. Sometimes, Etopxel 100 Injection 5 ml may use certain side effects such as myelosuppression (bone marrow activity is decreased), leucopenia (reduction in the number of white cells in the blood), thrombocytopenia (deficiency of platelets), anaemia (deficiency of red cells), anorexia (lack or loss of appetite for food), fatigue (extreme tiredness), drowsiness, nausea, vomiting, alopecia, liver and kidney functional impairment, leukaemia, hypotension, haemorrhage, abdominal pain, diarrhoea, stomatitis (inflammation of the mucous membrane), hepatic dysfunction and increased bilirubin levels etc. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic or hypersensitive to any component present in the Etopxel 100 Injection 5 ml or if you are pregnant, plan to have a baby or are breastfeeding. You should not become pregnant or breastfeed while receiving an etoposide injection. If you become pregnant while on treatment with etoposide, call your doctor. Before taking the Etopxel 100 Injection 5 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Etopxel 100 Injection 5 ml.

Etopxel 100 Injection 5 ml is a chemotherapeutic medication that contains Etoposide. It is primarily used with other medications to treat testicular cancer that has not improved or worsened after treatment with other medications or radiation therapy. Etoposide injection is also used in conjunction with other drugs to treat a certain kind of lung cancer (small cell lung cancer; SCLC). It can also be used to treat monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Etopxel 100 Injection 5 ml acts by blocking an enzyme that promotes cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are halted or inhibited.

• Myelosuppression (bone marrow activity is decreased)
• Leucopenia (reduction in the number of white cells in the blood)
• Thrombocytopenia (deficiency of platelets)
• Anaemia (deficiency of red cells)
• Anorexia (lack or loss of appetite for food)
• Fatigue (extreme tiredness)
• Drowsiness
• Nausea
• Vomiting
• Alopecia (hair loss)
• Liver impairment
• Kidney impairment
• Leukaemia (cancer of the white blood cell)
• Hypotension
• Haemorrhage (loss of blood from damaged blood vessels)
• Abdominal pain
• Diarrhoea
• Stomatitis (inflammation of the mucous membrane)
• Increased bilirubin levels

Etopxel 100 Injection 5 ml is not recommended to use if you are allergic to etoposide, podophyllotoxines or podophyllotoxin-derivatives or any other ingredients of this medicine; If your liver is not working properly; If your bone marrow does not produce enough blood cells; If you are breast-feeding; If you have a weak immune system and you are being vaccinated against yellow fever at the same time. So, inform your doctor about your medical history and ongoing therapies. Etoposide can significantly reduce the number of blood cells in your bone marrow. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. A decrease in the number of blood cells in your body might produce symptoms and raise your chance of developing a serious infection or bleeding. If you notice any of the following symptoms, contact your doctor immediately.

Drug-Drug Interactions: Etopxel 100 Injection 5 ml may interact with anti-coagulants (e.g. warfarin), immunosuppressants (e.g. cyclosporine), other anti-cancer medications(e.g. cisplatin), live vaccines (e.g. yellow fever), a medicine used in the treatment of epilepsy (e.g. phenytoin) and medicines used to treat inflammation, mild to moderate pain, and fever (e.g. phenylbutazone, sodium salicylate, acetylsalicylic acid).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Etopxel 100 Injection 5 ml may interact with disease conditions, including Myelosuppression (decrease in bone marrow activity), active infections, and renal dysfunction.

• WARFARIN
• CYCLOSPORINE
• CISPLATIN
• YELLOW FEVER VACCINE
• PHENYTOIN
• PHENYLBUTAZONE
• SODIUM SALICYCLATE
• ACETYLSALICYLIC ACID

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fibre content. Also, eat small and frequent meals for a speedy recovery.
• Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

• A blood test is required to monitor liver function and blood cells while taking Etopxel 100 Injection 5 ml.
• Do not have immunizations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterwards.
• Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Small-cell lung cancer: Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Leukaemia: Leukaemia is a type of blood cancer that affects blood cells in your bone marrow, usually white blood cells. Many types exist, such as monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4).