Etobrix-P 60/325 Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to relieve pain and inflammation in the conditions such as osteoarthritis, rheumatoid arthritis, gouty arthritis, ankylosing spondylitis, tooth pain, headache, nerve pain, muscular pain, back pain, fever, cold, and flu. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Etobrix-P 60/325 Tablet is a combination of two drugs, namely: Etoricoxib and Paracetamol. Etobrix-P 60/325 Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandin, which causes pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Etobrix-P 60/325 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as flatulence, constipation, nausea, diarrhoea, and swelling of hands and feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Etobrix-P 60/325 Tablet may cause sleepiness and dizziness, so drive with caution. Etobrix-P 60/325 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Etobrix-P 60/325 Tablet is a combination of two Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), namely: Etoricoxib and Paracetamol. Etobrix-P 60/325 Tablet is used to relieve pain in osteoarthritis, rheumatoid arthritis, gouty arthritis and ankylosing spondylitis, tooth pain, headache, nerve pain, muscular pain, back pain, fever, cold, and flu. Etobrix-P 60/325 Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical prostaglandin. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

• Flatulence
• Constipation
• Nausea
• Diarrhoea
• Swelling of hands and feet (oedema)
• Skin rash

Do not take Etobrix-P 60/325 Tablet if you are allergic to Etobrix-P 60/325 Tablet or other NSAIDs. Inform your doctor if you have stomach ulcers, or have suffered bleeding problems, clotting problems, inflammatory bowel disease, heart failure, high blood pressure, diabetes, high cholesterol, severe heart, liver or kidney problems. If you have had any recent heart surgery, do not take Etobrix-P 60/325 Tablet unless prescribed by the doctor, as Etobrix-P 60/325 Tablet may increase the risk of heart attack or stroke. Consult your doctor if you are pregnant or breastfeeding. Etobrix-P 60/325 Tablet may cause sleepiness and dizziness, so drive only if you are alert. Etobrix-P 60/325 Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Etobrix-P 60/325 Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Etobrix-P 60/325 Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Etobrix-P 60/325 Tablet unless prescribed. 

Drug-Drug Interactions: Etobrix-P 60/325 Tablet may interact with pain killers (aspirin), bronchodilators (salbutamol), anti-depressants (lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, ramipril, losartan, valsartan, minoxidil), antibiotics (rifampicin), antacid (ranitidine), blood thinners (warfarin), immunosuppressants (cyclosporine, tacrolimus), anti-emetic (metoclopramide, domperidone), bile-acid sequestrant (cholestyramine).

Drug-Food Interactions: Avoid alcohol consumption while taking Etobrix-P 60/325 Tablet as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcers, blood disorders, stomach disorders, diabetes, high blood pressure, high cholesterol, heart, kidney or liver problems.

• ASPIRIN
• WARFARIN
• SALBUTAMOL
• LITHIUM
• ENALAPRIL
• RAMIPRIL
• LOSARTAN
• VALSARTAN
• MINOXIDIL
• DIGOXIN
• RIFAMPICIN
• RANITIDINE
• CYCLOSPORINE
• TACROLIMUS
• METOCLOPRAMIDE
• DOMPERIDONE
• CHOLESTYRAMINE

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20minutes regularly.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

• Etobrix-P 60/325 Tablet might cause changes in blood tests. Inform the person doing the tests that you are taking Etobrix-P 60/325 Tablet .

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Gouty arthritis: It is caused due to deposits of excess uric acid crystals in the joints, which leads to pain and inflammation in the joints. Symptoms include pain, swelling, and redness in the joints, mostly the big toe.