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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:47 PM IST
Estizide 4mg Tablet is used to treat schizophrenia and Tourette syndrome. It contains Pimozide which works by inhibiting the receptor (dopamine) in the brain that regulates mood, behaviour and emotions. In some cases, this medicine may cause side effects such as drowsiness, excessive sweating, dizziness, dry mouth, constipation, weight gain, and blurred vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Composition

PIMOZIDE-4MG

Manufacturer/Marketer

Esteem Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Estizide 4mg Tablet

Estizide 4mg Tablet belongs to a class of medication called antipsychotics used to treat neurological and psychiatric disorders such as schizophrenia (a mental illness). Also, Estizide 4mg Tablet may be used to treat Tourette’s syndrome (neurological disorder). Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly. Tourette’s syndrome is a disorder of the nervous system that causes repetitive, involuntary movements or sounds called tics.

Estizide 4mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, it helps in lowering the number of tics in Tourette’s syndrome patients.

Take Estizide 4mg Tablet as prescribed by your doctor. You are advised to take Estizide 4mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience drowsiness, excessive sweating, dizziness, urinating at night, dry mouth, constipation, weight gain, blurred vision or impotence (erectile dysfunction) in men. Most of these side effects of Estizide 4mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Estizide 4mg Tablet or any other medicines, please tell your doctor. Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid taking Estizide 4mg Tablet if you are pregnant, especially in the third trimester as it may cause adverse effects in the baby. Therefore, inform your doctor if you are pregnant or breastfeeding. Estizide 4mg Tablet should be used with caution in elderly patients above 65 years with dementia (decline in memory, behaviour, thinking and ability to do daily activities). Please do not drink alcohol with Estizide 4mg Tablet as it may increase drowsiness and other adverse effects. Avoid driving as Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness.

Uses of Estizide 4mg Tablet

Treatment of Schizophrenia, Tourette’s syndrome.

Medicinal Benefits

Estizide 4mg Tablet contains Pimozide, an antipsychotic drug used to treat schizophrenia (a mental illness) and Tourette’s syndrome (neurological disorder). Estizide 4mg Tablet inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, it helps in lowering the number of tics in Tourette’s syndrome patients.

Directions for Use

Take Estizide 4mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Estizide 4mg Tablet

  • Drowsiness
  • Excessive sweating
  • Weakness
  • Nervousness
  • Restlessness
  • Orthostatic hypotension
  • Unusual hunger or thirst
  • Changes in posture
  • Speech problems
  • Dizziness
  • Urinating at night
  • Dry mouth
  • Constipation
  • Weight gain
  • Blurred vision
  • Impotence (erectile dysfunction) 

Drug Warnings

If you are allergic to Estizide 4mg Tablet or any other medicines, please tell your doctor. Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid taking Estizide 4mg Tablet if you are pregnant, especially in the third trimester as it may cause adverse effects in the baby. Therefore, inform your doctor if you are pregnant or breastfeeding. Estizide 4mg Tablet should be used with caution in elderly patients above 65 years with dementia (decline in memory, behaviour, thinking and ability to do daily activities). Avoid taking Estizide 4mg Tablet if you have Parkinson’s disease, depression, low levels of electrolytes in the blood, irregular heartbeat, bradycardia (slow heartbeat) or other heart problems. Avoid drinking alcohol with Estizide 4mg Tablet as it may increase drowsiness and other adverse effects. Avoid driving as Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness.

Drug Interactions

Drug-Drug Interaction: Estizide 4mg Tablet may interact with antifungals (miconazole, fluconazole, ketoconazole, itraconazole), antibiotics (clarithromycin, azithromycin, troleandomycin, erythromycin), heart-related medicines (disopyramide, procainamide, quinidine, amiodarone, sotalol, bretylium), antiallergic drugs (terfenadine), antimalarial drugs (mefloquine, quinine), antidepressants (maprotiline, sertraline, paroxetine, escitalopram, nefazodone, amitriptyline, citalopram), antipsychotics (sertindole, chlorpromazine, thioridazine), medicines for digestive problems (cisapride), drugs for weight control (sibutramine), drugs to treat HIV/AIDS (ritonavir, saquinavir, indinavir), opioid pain killers (codeine), anticonvulsants (lamotrigine, phenytoin, pregabalin), antiparkinson drug (levodopa).

Drug-Food Interaction: Avoid grapefruit or grapefruit juice with $name as it may increase the levels of Estizide 4mg Tablet in the body and affect heart rhythm. Also, avoid alcohol consumption with Estizide 4mg Tablet it may increase the risk of drowsiness and other adverse effects.

Drug-Disease Interaction: Avoid taking Estizide 4mg Tablet if you have Parkinson’s disease, depression, low levels of electrolytes in the blood, irregular heartbeat, bradycardia (slow heartbeat) or other heart problems. If you have fits, thyroid gland problems, kidney, liver or heart problems, phaeochromocytoma (tumour in the adrenal gland) or have a history of blood clots, inform your doctor before taking Estizide 4mg Tablet.

 

Drug-Drug Interactions Checker List

  • MICONAZOLE
  • FLUCONAZOLE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • TROLEANDOMYCIN
  • ERYTHROMYCIN
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • BRETYLIUM
  • TERFENADINE
  • MEFLOQUINE
  • QUININE
  • MAPROTILINE
  • SERTRALINE
  • PAROXETINE
  • ESCITALOPRAM
  • NEFAZODONE
  • AMITRIPTYLINE
  • CITALOPRAM
  • SERTINDOLE
  • CHLORPROMAZINE
  • THIORIDAZINE
  • CISAPRIDE
  • SIBUTRAMINE
  • RITONAVIR
  • SAQUINAVIR
  • INDINAVIR
  • CODEINE
  • LAMOTRIGINE
  • PHENYTOIN
  • PREGABALIN
  • LEVODOPA

Habit Forming

No

Diet & Lifestyle Advise

  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Estizide 4mg Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

  • ECG (electrocardiogram) is recommended before and while taking Estizide 4mg Tablet to measure the electrical activity of your heart.
  • Blood tests are recommended while taking Estizide 4mg Tablet to monitor the levels of electrolytes (minerals) in the blood.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects the ability of a person to feel, think and behave clearly. The symptoms include hallucinations, thought or movement disorders, delusions (misbelief), lack of emotion, sleep problems, isolating oneself from family and friends, difficulty in doing daily activities.

Tourette’s syndrome: Tourette’s syndrome is a disorder of the nervous system that causes repetitive, involuntary movements or sounds called tics such as repeatedly blinking the eyes, blurt out offensive words not intended to say or shrugging shoulders. It starts in childhood or adolescence. The treatment includes psychological therapies or/and medication.

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Alcohol

Unsafe

Avoid consumption of alcohol with Estizide 4mg Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Estizide 4mg Tablet is not recommended for use during pregnancy especially in the third trimester as it may cause unwanted side effects to the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Estizide 4mg Tablet is usually not recommended for breastfeeding mothers as it may be excreted in human milk in small amounts. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Estizide 4mg Tablet.

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Liver

Caution

Take Estizide 4mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Estizide 4mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

E-69 Site-Csikandra Agra Uttar Pradesh Ur 000000 In
Other Info - ESTI247

Author Details

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FAQs

Estizide 4mg Tablet is used to treat schizophrenia and tourette' s syndrome.
Estizide 4mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, helps in lowering the number of tics in Tourette’s syndrome patients.
You are not recommended to take Estizide 4mg Tablet with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Estizide 4mg Tablet with any other medicines.
Estizide 4mg Tablet is not recommended for elderly people with dementia (decline in memory, behaviour, thinking and ability to do daily activities) as it may increase the risk of life-threatening adverse effects. Therefore, inform your doctor if you have dementia before taking Estizide 4mg Tablet.
Estizide 4mg Tablet may cause dizziness as a temporary adverse effect. However, if the condition persists or worsens, please consult a doctor.
Estizide 4mg Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Estizide 4mg Tablet.
Estizide 4mg Tablet may cause side effects like drowsiness, excessive sweating, dizziness, urinating at night, dry mouth, constipation, weight gain, blurred vision or impotence (erectile dysfunction) in men. Most of these side effects of Estizide 4mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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