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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Estizide 4mg Tablet is used to treat schizophrenia and Tourette syndrome. It contains Pimozide which works by inhibiting the receptor (dopamine) in the brain that regulates mood, behaviour and emotions. In some cases, this medicine may cause side effects such as drowsiness, excessive sweating, dizziness, dry mouth, constipation, weight gain, and blurred vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

PIMOZIDE-4MG

Manufacturer/Marketer :

Esteem Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Estizide 4mg Tablet

Estizide 4mg Tablet belongs to a class of medication called antipsychotics used to treat neurological and psychiatric disorders such as schizophrenia (a mental illness). Also, Estizide 4mg Tablet may be used to treat Tourette’s syndrome (neurological disorder). Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly. Tourette’s syndrome is a disorder of the nervous system that causes repetitive, involuntary movements or sounds called tics.

Estizide 4mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, it helps in lowering the number of tics in Tourette’s syndrome patients.

Take Estizide 4mg Tablet as prescribed by your doctor. You are advised to take Estizide 4mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience drowsiness, excessive sweating, dizziness, urinating at night, dry mouth, constipation, weight gain, blurred vision or impotence (erectile dysfunction) in men. Most of these side effects of Estizide 4mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Estizide 4mg Tablet or any other medicines, please tell your doctor. Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid taking Estizide 4mg Tablet if you are pregnant, especially in the third trimester as it may cause adverse effects in the baby. Therefore, inform your doctor if you are pregnant or breastfeeding. Estizide 4mg Tablet should be used with caution in elderly patients above 65 years with dementia (decline in memory, behaviour, thinking and ability to do daily activities). Please do not drink alcohol with Estizide 4mg Tablet as it may increase drowsiness and other adverse effects. Avoid driving as Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness.

Uses of Estizide 4mg Tablet

Treatment of Schizophrenia, Tourette’s syndrome.

Directions for Use

Take Estizide 4mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Estizide 4mg Tablet contains Pimozide, an antipsychotic drug used to treat schizophrenia (a mental illness) and Tourette’s syndrome (neurological disorder). Estizide 4mg Tablet inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, it helps in lowering the number of tics in Tourette’s syndrome patients.

How Estizide 4mg Tablet Works

Estizide 4mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, it helps in lowering the number of tics in Tourette’s syndrome patients.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Estizide 4mg Tablet

  • Drowsiness
  • Excessive sweating
  • Weakness
  • Nervousness
  • Restlessness
  • Orthostatic hypotension
  • Unusual hunger or thirst
  • Changes in posture
  • Speech problems
  • Dizziness
  • Urinating at night
  • Dry mouth
  • Constipation
  • Weight gain
  • Blurred vision
  • Impotence (erectile dysfunction) 

What if I have taken an overdose of Estizide 4mg Tablet

Take Estizide 4mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include blank facial expression, shuffling walk, unusual, slowed, or uncontrollable movements of any part of the body, restlessness, fast heartbeat, drowsiness, coma (loss of consciousness for a period of time), and difficulty breathing. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Estizide 4mg Tablet or any other medicines, please tell your doctor. Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid taking Estizide 4mg Tablet if you are pregnant, especially in the third trimester as it may cause adverse effects in the baby. Therefore, inform your doctor if you are pregnant or breastfeeding. Estizide 4mg Tablet should be used with caution in elderly patients above 65 years with dementia (decline in memory, behaviour, thinking and ability to do daily activities). Avoid taking Estizide 4mg Tablet if you have Parkinson’s disease, depression, low levels of electrolytes in the blood, irregular heartbeat, bradycardia (slow heartbeat) or other heart problems. Avoid drinking alcohol with Estizide 4mg Tablet as it may increase drowsiness and other adverse effects. Avoid driving as Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness.

Drug-Drug Interactions

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PimozideParoxetine
Critical
PimozideOxytocin
Critical

Drug-Drug Interactions

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PimozideParoxetine
Critical
How does the drug interact with Estizide 4mg Tablet:
Combining Paroxetine with Estizide 4mg Tablet can effect the rhythm of the heart

How to manage the interaction:
Taking Paroxetine with Estizide 4mg Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideOxytocin
Critical
How does the drug interact with Estizide 4mg Tablet:
Coadministration of oxytocin with Estizide 4mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Estizide 4mg Tablet with Oxytocin is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideTerbinafine
Critical
How does the drug interact with Estizide 4mg Tablet:
Co-administration of Estizide 4mg Tablet and Terbinafine can increase the blood levels of Estizide 4mg Tablet and the risk of side effects.

How to manage the interaction:
Co-administration of Estizide 4mg Tablet and Terbinafine is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PimozideHaloperidol
Critical
How does the drug interact with Estizide 4mg Tablet:
Combining Estizide 4mg Tablet and Haloperidol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Estizide 4mg Tablet and Haloperidol together is generally avoided as it can lead to an interaction, it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PimozideChloroquine
Critical
How does the drug interact with Estizide 4mg Tablet:
When Estizide 4mg Tablet and Chloroquine are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Chloroquine with Estizide 4mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
PimozideTetrabenazine
Critical
How does the drug interact with Estizide 4mg Tablet:
Coadministration of Estizide 4mg Tablet and Tetrabenazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Estizide 4mg Tablet and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea, or vomiting. Do not discontinue any medications without consulting your doctor.
PimozideDiltiazem
Critical
How does the drug interact with Estizide 4mg Tablet:
When Estizide 4mg Tablet and Diltiazem are taken together, the body's ability to break down Estizide 4mg Tablet may be reduced.

How to manage the interaction:
Taking Diltiazem with Estizide 4mg Tablet is not recommended, please consult your doctor before taking it.
PimozideLenvatinib
Critical
How does the drug interact with Estizide 4mg Tablet:
Coadministration of Lenvatinib with Estizide 4mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although using Lenvatinib and Estizide 4mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
PimozideSorafenib
Critical
How does the drug interact with Estizide 4mg Tablet:
Using Estizide 4mg Tablet together with Sorafenib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sorafenib with Estizide 4mg Tablet can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without consulting a doctor.
PimozideDanazol
Critical
How does the drug interact with Estizide 4mg Tablet:
Using Estizide 4mg Tablet together with danazol may significantly increase the blood levels of Estizide 4mg Tablet.

How to manage the interaction:
Taking Danazol with Estizide 4mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Estizide 4mg Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

NEUROLEPTIC

Estizide 4mg Tablet Substitute

Substitutes safety advice
  • PIMIDE 4MG TABLET

    9.86per tablet
  • MOZEP 4MG TABLET

    11.25per tablet
  • Neurap 4mg Tablet

    3.80per tablet
  • Pimo 4mg Tablet

    4.10per tablet
  • Monozide 4mg Tablet

    1.71per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Estizide 4mg Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Estizide 4mg Tablet is not recommended for use during pregnancy especially in the third trimester as it may cause unwanted side effects to the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Estizide 4mg Tablet is usually not recommended for breastfeeding mothers as it may be excreted in human milk in small amounts. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Estizide 4mg Tablet may cause dizziness, blurred vision or drowsiness. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Estizide 4mg Tablet.

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Liver

Caution

Take Estizide 4mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Estizide 4mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Estizide 4mg Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

FAQs

Estizide 4mg Tablet is used to treat schizophrenia and tourette' s syndrome.
Estizide 4mg Tablet contains Pimozide that works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Estizide 4mg Tablet prevents dopamine overactivity and helps in controlling psychotic illness. Also, Estizide 4mg Tablet decreases uncontrolled movements or outbursts of sounds or words (tics). Thus, helps in lowering the number of tics in Tourette’s syndrome patients.
You are not recommended to take Estizide 4mg Tablet with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Estizide 4mg Tablet with any other medicines.
Estizide 4mg Tablet is not recommended for elderly people with dementia (decline in memory, behaviour, thinking and ability to do daily activities) as it may increase the risk of life-threatening adverse effects. Therefore, inform your doctor if you have dementia before taking Estizide 4mg Tablet.
Estizide 4mg Tablet may cause dizziness as a temporary adverse effect. However, if the condition persists or worsens, please consult a doctor.
Estizide 4mg Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Estizide 4mg Tablet.
Estizide 4mg Tablet may cause side effects like drowsiness, excessive sweating, dizziness, urinating at night, dry mouth, constipation, weight gain, blurred vision or impotence (erectile dysfunction) in men. Most of these side effects of Estizide 4mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

E-69 Site-Csikandra Agra Uttar Pradesh Ur 000000 In
Other Info - ESTI247

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