Estadiol Tablet 28's is indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. Estadiol Tablet 28's is prescribed when the body is not producing a sufficient amount of natural estrogen.

Estadiol Tablet 28's contains estradiol, which regulates the menstrual cycle and ovulation. Estadiol Tablet 28's works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. 

You are advised to take Estadiol Tablet 28's for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience headaches, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Estadiol Tablet 28's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Estadiol Tablet 28's. While taking Estadiol Tablet 28's, your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Estadiol Tablet 28's.

Estadiol Tablet 28's contains a synthetic female hormone that regulates ovulation and menstruation in women. Estadiol Tablet 28's is given as a hormone replacement therapy for estrogen. It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness.

• Headache
• Bloating
• Hair loss
• Nausea
• Weight gain
• Breast pain
• Irregular vaginal bleeding

Do not take Estadiol Tablet 28's if you are allergic to any of its ingredients. Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure, if you are pregnant or breastfeeding. Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Estadiol Tablet 28's. Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Estadiol Tablet 28's. 

Drug-Drug Interaction: Estadiol Tablet 28's is known to interact with anti-epileptic medicines (carbamazepine, phenytoin), medicines for infections (griseofulvin, rifampicin), medicines for viral infections (efavirenz, ritonavir, nelfinavir), high blood pressure (Bosentan), blood thinner (aspirin).

Drug-Food Interaction: Estadiol Tablet 28's is known to interact with grapefruit juice and St. John’s wort (a natural remedy for depression).

Drug-Disease Interaction: Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), or high blood pressure.

• CARBAMAZEPINE
• PHENYTOIN
• GRISEOFULVIN
• RIFAMPICIN
• RITONAVIR
• NELFINAVIR
• EFAVIRENZ
• BOSENTAN
• ASPIRIN

• Regular exercise and physical activity can minimize hot flashes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
• Wear loose clothes before going to bed and sleep in a cool, well-ventilated room. This can prevent symptoms of hot flashes and night sweats. Get a minimum of 8 hours of sleep. 
• Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
• Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
• Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Hypoestrogenism: It refers to the lowered secretion of the natural female sex hormone known as estrogen. It is an umbrella term used for estrogen deficiency in various conditions. Its abnormalities may lead to infertility, bone loss, and lipid abnormalities.

Osteoporosis: Osteoporosis means the bone has become porous. It is a disease in which too much bone is lost, and the body makes relatively little bone. As a result, bones become weak and can break easily if you fall.

Hormone replacement therapy (HRT): It is a treatment to relieve symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.