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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Espin-1.25 Tablet is used to treat high blood pressure and angina (chest pain). It contains S-amlodipine which works by relaxing the blood vessels; this reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. In some cases, this medicine may cause side effects such as fatigue, headache, nausea, dizziness, and abdominal pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

S AMLODIPINE-1.25MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Espin-1.25 Tablet

Espin-1.25 Tablet is used to treat hypertension (high blood pressure) and angina (chest pain). Hypertension (high blood pressure) is a lifelong or chronic condition in which the blood pressure against the artery walls becomes high. The higher this blood pressure, the harder the heart has to pump. 

Espin-1.25 Tablet contains 'S-amlodipine', a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take Espin-1.25 Tablet with or without food as prescribed by your doctor with a full glass of water. Espin-1.25 Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines, depending upon your blood pressure levels. Inform your doctor if you are taking any other anti-hypertensive medicine. You may have common side effects like fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain that usually resolves after some time. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and do not stop taking it suddenly without consulting your doctor.

Inform your doctor if you are allergic to Espin-1.25 Tablet . Inform your doctor if you are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, Shock (including cardiogenic shock), obstruction of the outflow tract of the left ventricle (e.g., high-grade aortic stenosis), unstable angina (excluding Prinzmetal's angina), severe hypotension, hemodynamically unstable heart failure after acute myocardial infarction.

Uses of Espin-1.25 Tablet

Treatment of High blood pressure (hypertension), Heart-related chest pain (angina), and Prevention of a heart attack.

Medicinal Benefits

Espin-1.25 Tablet is used to treat heart-related conditions like angina (chest pain) and high blood pressure (hypertension). It is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart which relaxes and widens the smooth muscles for better blood flow. Besides this, Espin-1.25 Tablet helps prevent sudden spasms of the coronary artery (blood vessels of the heart) and reduces how hard the heart has to pump blood around the body, lowering its oxygen requirements. It improves an individual’s tolerance to physical activity and exercise and keeps their blood pressure normal during exercise. As a result, it overall protects your heart and keeps your heart healthy.

Side Effects of Espin-1.25 Tablet

  • Fatigue

  • Ankle swelling

  • Sleepiness

  • Flushing (sense of warmth in the face, ears, neck, and trunk)

  • Headache

  • Difficulty in breathing

  • Blurred vision

  • Diarrhea

  • Irregular heartbeat

  • Chest tightness

  • Black or tarry stools

  • Nausea

  • Dizziness

  • Palpitations

  • Abdominal pain

Directions for Use

Take Espin-1.25 Tablet with or without food or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Espin-1.25 Tablet should not be given to people allergic to Espin-1.25 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women without the prescription of a doctor. Besides this, it is contraindicated in patients with aortic stenosis (heart valve problem). Espin-1.25 Tablet can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Espin-1.25 Tablet and breastfeeding. Espin-1.25 Tablet is not recommended for use in patients with a known history of hypotension or cardiogenic shock due to the increased risk of worsening the patient's condition. Espin-1.25 Tablet should be used with caution in patients with coronary artery disease due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Drug Interactions

verifiedApollotooltip
S-AmlodipineSimvastatin
Severe
S-AmlodipineCeritinib
Severe

Drug-Food Interactions

verifiedApollotooltip
S AMLODIPINE-1.25MGCalcium rich foods
Moderate

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of  19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

What if I have taken an overdose of Espin-1.25 Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include excessive peripheral vasodilation with marked low blood pressure and reflex tachycardia. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ESP0007

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