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Espin-1.25 Tablet 10's

Espin-1.25 Tablet 10's

Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Espin-1.25 Tablet

Espin-1.25 Tablet is used to treat hypertension (high blood pressure) and angina (chest pain). Hypertension (high blood pressure) is a lifelong or chronic condition in which the blood pressure against the artery walls becomes high. The higher this blood pressure, the harder the heart has to pump. 

Espin-1.25 Tablet contains 'S-amlodipine', a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take Espin-1.25 Tablet with or without food as prescribed by your doctor with a full glass of water. Espin-1.25 Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines, depending upon your blood pressure levels. Inform your doctor if you are taking any other anti-hypertensive medicine. You may have common side effects like fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain that usually resolves after some time. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and do not stop taking it suddenly without consulting your doctor.

Inform your doctor if you are allergic to Espin-1.25 Tablet . Inform your doctor if you are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, Shock (including cardiogenic shock), obstruction of the outflow tract of the left ventricle (e.g., high-grade aortic stenosis), unstable angina (excluding Prinzmetal's angina), severe hypotension, hemodynamically unstable heart failure after acute myocardial infarction.

Uses of Espin-1.25 Tablet

Treatment of High blood pressure (hypertension), Heart-related chest pain (angina), and Prevention of a heart attack.

Medicinal Benefits

Espin-1.25 Tablet is used to treat heart-related conditions like angina (chest pain) and high blood pressure (hypertension). It is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart which relaxes and widens the smooth muscles for better blood flow. Besides this, Espin-1.25 Tablet helps prevent sudden spasms of the coronary artery (blood vessels of the heart) and reduces how hard the heart has to pump blood around the body, lowering its oxygen requirements. It improves an individual’s tolerance to physical activity and exercise and keeps their blood pressure normal during exercise. As a result, it overall protects your heart and keeps your heart healthy.

Directions for Use

Take Espin-1.25 Tablet with or without food or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Espin-1.25 Tablet

  • Fatigue

  • Ankle swelling

  • Sleepiness

  • Flushing (sense of warmth in the face, ears, neck, and trunk)

  • Headache

  • Difficulty in breathing

  • Blurred vision

  • Diarrhea

  • Irregular heartbeat

  • Chest tightness

  • Black or tarry stools

  • Nausea

  • Dizziness

  • Palpitations

  • Abdominal pain

Drug Warnings

Espin-1.25 Tablet should not be given to people allergic to Espin-1.25 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women without the prescription of a doctor. Besides this, it is contraindicated in patients with aortic stenosis (heart valve problem). Espin-1.25 Tablet can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Espin-1.25 Tablet and breastfeeding. Espin-1.25 Tablet is not recommended for use in patients with a known history of hypotension or cardiogenic shock due to the increased risk of worsening the patient's condition. Espin-1.25 Tablet should be used with caution in patients with coronary artery disease due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Drug Interactions

Drug-Drug Interactions: Espin-1.25 Tablet may interact with high blood pressure lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide), drugs used to control lipid levels in the blood (atorvastatin, simvastatin), medicines to treat erectile dysfunction (sildenafil), antibiotics (clarithromycin, erythromycin, rifampin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (cyclosporine, tacrolimus), cardiac glycoside (digoxin), blood thinners (warfarin), and painkillers (ibuprofen, aspirin).

Drug-Food Interactions: Avoid foods with high fat or cholesterol. Avoid too much salt in your diet like pickles, and extra salt on salad. Avoid Espin-1.25 Tablet with grapefruit juice.

Drug-Disease Interactions: Espin-1.25 Tablet should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), liver disease, heart failure, kidney disease.

Drug-Drug Interactions Checker List

  • BENAZEPRIL
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SIMVASTATIN
  • SILDENAFIL
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • RIFAMPIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CYCLOSPORINE
  • TACROLIMUS
  • DIGOXIN
  • WARFARIN
  • IBUPROFEN
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of  19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Special Advise

  • Espin-1.25 Tablet is generally advised for treatment of high blood pressure and other heart conditions.

  • Espin-1.25 Tablet should be taken at the same time every day for its maximum effects to be seen and for increased compliance.

  • Consumption of Espin-1.25 Tablet may cause dizziness. Avoid activities like driving while on this medication.

  • A sudden drop in blood pressure may be seen while on this medication which might lead to dizziness. Changing your posture at a slower rate might help counter this. 

  • Ankle swelling is sometimes seen as a side effect of this drug. Consult your doctor if this or other side effects cause trouble or are persistent.

Disease/Condition Glossary

Hypertension: Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor. Systolic pressure is the pressure with which the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

Angina (chest pain): Angina is a type of chest pain caused by reduced blood flow to the heart. Angina feels like squeezing, pressure, heaviness, tightness, or pain in the chest. It can be sudden or recur over time.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Espin-1.25 Tablet to avoid unpleasant side effects like lowering of blood pressure (hypotension).

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Pregnancy

Caution

Espin-1.25 Tablet is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking Espin-1.25 Tablet .

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Breast Feeding

Caution

Espin-1.25 Tablet is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine

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Driving

Unsafe

Drive with caution, Espin-1.25 Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Espin-1.25 Tablet should be used with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Espin-1.25 Tablet is generally safe to prescribe in patients with kidney diseases, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending upon the severity of your condition.

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Children

Caution

Espin-1.25 Tablet can be given safely to children aged 6-12 years provided, the dose has been prescribed by a child specialist. Espin-1.25 Tablet should not be given to the children without consulting a child specialist.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ESP0007

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Espin-1.25 Tablet is used to treat hypertension (high blood pressure) and angina (chest pain).
Espin-1.25 Tablet contains S-amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.
The common side effects of Espin-1.25 Tablet are fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain resolves after some time.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and will not recommend discontinuing it.
In case you have missed a dose of Espin-1.25 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both doses together. Take only one dose, taking a double dose of Espin-1.25 Tablet will lead to low blood pressure.
Yes, Espin-1.25 Tablet is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
No, you should notify your doctor and monitor your blood pressure for at least two weeks before quitting the medication. Depending on your current blood pressure readings, your doctor may reduce your drug dosage but will not advocate quitting it.
Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.
Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.
Espin-1.25 Tablet begins to act on the day you take it, but it may take a few weeks before it has full effect.
Espin-1.25 Tablet may cause itching, although it is not common in everyone. It usually fades with time; however, contact your doctor if you experience severe itching.
Espin-1.25 Tablet is generally safe to prescribe in patients with mild kidney dysfunctions, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending on the severity of your condition.
You can take it at any time of day but try to make sure it's around the same time every day.
Usually, treatment with Espin-1.25 Tablet is long term, even for the rest of your life. Talk to your doctor if you want to stop taking Espin-1.25 Tablet .
No, Espin-1.25 Tablet is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers.
More frequent or more severe chest pain, rapid, pounding, or irregular heartbeat and fainting. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.
Espin-1.25 Tablet does not interfere with contraception. However, some hormonal methods of contraception, such as the combination pill and contraceptive patch, are generally not indicated if you have high blood pressure.
Consuming significant amounts of grapefruit or grapefruit juice can raise the levels of amlodipine in your blood and exacerbate adverse effects. If you are affected, you may need to avoid eating or drinking grapefruit while taking amlodipine. Also, avoid alcohol consumption, quit smoking, and limit salt intake (Aim for no more than 6g of salt a day).
If oedema occurs while taking amlodipine, stop using it and consult your healthcare provider right away.
Drinking alcohol can make amlodipine lower your blood pressure more than you need. This can make you sleepy or dizzy or bring on a headache.
Espin-1.25 Tablet can make some people feel dizzy. If this happens to you, do not drive a car, ride a bike, or use tools or machinery until you feel better.
Espin-1.25 Tablet contains S-amlodipine, a calcium channel blocker.
Espin-1.25 Tablet is generally safe to take for a long time. In fact, it works best when you take it for a long time.
Espin-1.25 Tablet can be given safely to children aged 6-12 years, provided a child specialist has prescribed the dose. Espin-1.25 Tablet should only be given to the children by consulting a child specialist.
Espin-1.25 Tablet is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking Espin-1.25 Tablet .
Avoid exceeding the recommended dose, as it could lead to an overdose. Symptoms of overdose may include excessive peripheral vasodilation with marked low blood pressure and reflex tachycardia. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

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