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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Espidase 5 mg Tablet 10's is used to provide pain relief in various conditions, including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis(joint pain and damage throughout the body). It contains Serratiopeptidase, which breaks the insoluble protein (fibrin) into smaller units. It also causes thinning of the body's fluids, making fluid drainage smoother in the swollen tissue and relieving inflammation at the affected or injured site. In some cases, it may cause stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Megha Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Espidase 5 mg Tablet 10's

Espidase 5 mg Tablet 10's belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID) used to provide pain relief in various conditions, including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis(joint pain and damage throughout the body). Pain can be temporary (acute) or prolonged period (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for life long, caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. 

Espidase 5 mg Tablet 10's contains 'serratiopeptidase', a protein enzyme isolated from a bacterial cell found in the silkworms. It breaks the insoluble protein (fibrin), a by-product of blood clots, into smaller units. It also causes thinning of the body's fluids due to injury, making fluid drainage smoother in the swollen tissue and relieving inflammation at the affected or injured site. 

Swallow Espidase 5 mg Tablet 10's as a whole with water; do not crush, break or chew it. In some cases, Espidase 5 mg Tablet 10's may cause stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Espidase 5 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Espidase 5 mg Tablet 10's if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Espidase 5 mg Tablet 10's may be associated with a small increased risk of heart attack ‘myocardial infarction’. It is advisable not to exceed the recommended dose or duration of treatment. Stop taking this medicine if you experience tightness of the chest, breathing difficulties, fever, skin rashes, mouth sores, and other mucous membranes causing ulcers, or any signs of hypersensitivity (allergy).

Uses of Espidase 5 mg Tablet 10's

Treatment of Pain, Inflammation.

Medicinal Benefits

Espidase 5 mg Tablet 10's plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers that cause pain and fever. Espidase 5 mg Tablet 10's relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Espidase 5 mg Tablet 10's contains serratiopeptidase, a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clots into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue. 

Side Effects of Espidase 5 mg Tablet 10's

  • Stomach ache
  • Diarrhoea
  • Nausea (feeling sick)
  • Indigestion

Directions for Use

Swallow Espidase 5 mg Tablet 10's as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Espidase 5 mg Tablet 10's as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Espidase 5 mg Tablet 10's. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin), or skin rashes, immediately stop taking Espidase 5 mg Tablet 10's. Do not drive or operate heavy machinery as intake of Espidase 5 mg Tablet 10's may cause dizziness. Patients who have had recently undergone heart bypass surgery should take Espidase 5 mg Tablet 10's with caution and only under medical supervision. Use of Espidase 5 mg Tablet 10's is contraindicated in kidney failure patients or who are undergoing dialysis.

Therapeutic Class

ANALGESICS

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

How Espidase 5 mg Tablet 10's Works

Espidase 5 mg Tablet 10's contains 'serratiopeptidase', a protein enzyme isolated from a bacterial cell found in the silkworms. It breaks the insoluble protein (fibrin), by-product of blood clots, into smaller units. It also causes thinning of the body's fluids due to injury, making fluid drainage smoother in the swollen tissue and relieving inflammation at the affected or injured site.

What if I have taken an overdose of Espidase 5 mg Tablet 10's

Do not take more than the prescribed dose of Espidase 5 mg Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Espidase 5 mg Tablet 10's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

The use of Espidase 5 mg Tablet 10's may impair female fertility and is not recommended in pregnant women or those planning for pregnancy.

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Breast Feeding

Unsafe

Espidase 5 mg Tablet 10's passes into the breast milk so it is not recommended for nursing mothers.

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Driving

Unsafe

Espidase 5 mg Tablet 10's may affect driving as it causes dizziness. So do not drive a motor vehicle or operate heavy machinery after taking Espidase 5 mg Tablet 10's.

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Liver

Caution

Espidase 5 mg Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Espidase 5 mg Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor

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Children

Unsafe

Espidase 5 mg Tablet 10's is not recommended for children under 10 years of age. For the dose has to be adjusted and recommended by a child specialist only.

Country of origin

India

Manufacturer/Marketer address

9 Luthra Premises, Andheri Kurla Road, Safed Pool, Andheri (E), Mumbai-400072.
Other Info - ESP0025

Author Details

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FAQs

Espidase 5 mg Tablet 10's is used to provide pain relief in various conditions, including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain and damage throughout the body).
A person who is allergic to pain-killers should not take this medicine as it can be harmful. It should also be avoided in a person with a history of heart failure, kidney or liver disease, stomach ulcers, and high blood pressure.
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation and pain in the joints. In this condition, our body attacks its own cells leading to arthritis.
Ankylosing spondylitis is arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.
Yes, Espidase 5 mg Tablet 10's can cause stomach upset in some cases. So, it should be preferably taken with food to avoid it.
No, Espidase 5 mg Tablet 10's is not a steroid. Espidase 5 mg Tablet 10's belongs to the class of drugs called anti-inflammatory agents used to relieve inflammation and pain.
No, Espidase 5 mg Tablet 10's is not addictive. It does not have habit-forming tendencies.
Yes, Espidase 5 mg Tablet 10's provides relief from toothache by reducing inflammation near affected dental tissue.
Espidase 5 mg Tablet 10's contains an enzyme called serratiopeptidase which works by modifying cell- surface adhesion molecules which are responsible for inflammation. Thereby, Espidase 5 mg Tablet 10's helps to treat inflammation.
No, people with known hypersensitivity to serratiopeptidase or blood clotting problems should not take Espidase 5 mg Tablet 10's. It should also be avoided in patients with a history of severe kidney or liver disease.
Side effects of Espidase 5 mg Tablet 10's include stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects resolve over time and do not require medical intervention. However, consult the doctor if the side effects persist or worsen.
Let the doctor know if you have any surgery scheduled within two weeks or if you are using anticoagulant medications. Consult your doctor before taking Espidase 5 mg Tablet 10's if you are pregnant and breastfeeding.
Store Espidase 5 mg Tablet 10's in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
Espidase 5 mg Tablet 10's contains serratiopeptidase, a proteolytic enzyme that helps treat inflammation associated with various conditions.
Espidase 5 mg Tablet 10's can treat medical conditions like post-traumatic pain, low back pain, cervical pain, spondylitis, osteoarthritis, and rheumatoid arthritis.

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