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  3. Esm-40 Tablet 10's

Esm-40 Tablet 10's, Pack of 10 TABLETS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Esm-40 Tablet reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour). It helps in reducing the stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn. In some cases, it may cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Monatis Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esm-40 Tablet

Esm-40 Tablet belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour).

Esm-40 Tablet helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Esm-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take Esm-40 Tablet 1-2 hours prior to food. You are advised to take Esm-40 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Esm-40 Tablet might cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen. 

Esm-40 Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Esm-40 Tablet , or will have an endoscopy in the future. Prolonged intake of Esm-40 Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium, and Vitamin D, leading to osteoporosis.

Uses of Esm-40 Tablet

Esm-40 Tablet is used in the treatment of hyperacidity, heartburn, stomach ulcer and zollinger-ellison syndrome. The detailed uses of Esm-40 Tablet are as follows:
• Management of Gastroesophageal Reflux Disease (GERD): Esm-40 Tablet effectively reduces symptoms of GERD, such as heartburn and acid regurgitation, by lowering stomach acid production.
• Healing of Erosive Esophagitis: Esm-40 Tablet is often prescribed to promote the healing of inflamed esophageal tissue caused by prolonged exposure to stomach acid.
• Treatment of Zollinger-Ellison Syndrome: Esm-40 Tablet is used to manage Zollinger-Ellison syndrome, a condition that leads to excessive stomach acid production.
• Prevention of Peptic Ulcers: Esm-40 Tablet helps prevent peptic ulcer formation, particularly in individuals undergoing long-term NSAID treatment.
• Eradication of Helicobacter pylori: Esm-40 Tablet is sometimes included in combination therapy to eliminate Helicobacter pylori infections, which are associated with peptic ulcers.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Esm-40 Tablet in doses as prescribed by your doctor with the help of a measuring cup. Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

Esm-40 Tablet is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. Esm-40 Tablet works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

How Esm-40 Tablet Works

Esm-40 Tablet helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Esm-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Esm-40 Tablet

  • Headache
  • Diarrhoea
  • Nausea
  • Abdominal pain
  • Vomiting

What if I have taken an overdose of Esm-40 Tablet

Do not take more than the prescribed dose of Esm-40 Tablet as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, sweating, nausea, fast heartbeat, dry mouth, headache or flushing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

You should avoid taking Esm-40 Tablet if you are allergic to Esm-40 Tablet or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Esm-40 Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Esm-40 Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Esm-40 Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
EsomeprazolePazopanib
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esm-40 Tablet:
Esm-40 Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esm-40 Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazolePazopanib
Severe
How does the drug interact with Esm-40 Tablet:
Esm-40 Tablet decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esm-40 Tablet and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleTacrolimus
Severe
How does the drug interact with Esm-40 Tablet:
Taking tacrolimus with Esm-40 Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Esm-40 Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esm-40 Tablet:
Taking nelfinavir with Esm-40 Tablet may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esm-40 Tablet and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Esm-40 Tablet:
Esm-40 Tablet may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Esm-40 Tablet with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Esm-40 Tablet:
Esm-40 Tablet can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esm-40 Tablet with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleAtazanavir
Severe
How does the drug interact with Esm-40 Tablet:
Esm-40 Tablet reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Esm-40 Tablet and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with Esm-40 Tablet:
Coadministration of erlotinib and Esm-40 Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Esm-40 Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Esm-40 Tablet:
Co-administration of methotrexate and Esm-40 Tablet can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esm-40 Tablet with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Esm-40 Tablet:
Using Dasatinib together with Esm-40 Tablet may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Esm-40 Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Esm-40 Tablet Substitute

Substitutes safety advice

  • Esomecare 40 Tablet 10's

    by Others

    ₹10.70per tablet

  • Nexpro-40 Tablet 15's

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    ₹11.37per tablet

  • Sompraz 40 Tablet 15's

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    ₹10.80per tablet

  • Neksium 40 mg Tablet 15's

    by Others

    ₹12.78per tablet

  • Nexpro Fast 40 Tablet 10's

    by Others

    ₹14.72per tablet

Product Substitutes

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Alcohol

Caution

Drinking alcohol with Esm-40 Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Esm-40 Tablet .

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Pregnancy

Caution

Esm-40 Tablet isn't usually recommended during pregnancy as there's no firm evidence it's safe. So, contact a doctor before intake of Esm-40 Tablet . Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Esm-40 Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Esm-40 Tablet . Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

In some cases, Esm-40 Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

Esm-40 Tablet should be taken with precaution in patients with liver disease.

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Kidney

Caution

Patients with kidney disease should consult a doctor before taking Esm-40 Tablet .

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Children

Caution

Esm-40 Tablet should not be prescribed for children under 5 years of age. Esm-40 Tablet is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

FAQs

Esm-40 Tablet is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.

Esm-40 Tablet is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

No. Esm-40 Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes. Esm-40 Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

There's no firm evidence to suggest that taking Esm-40 Tablet will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

You can eat and drink normally while taking Esm-40 Tablet . However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Prolonged intake of Esm-40 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

Esm-40 Tablet should be used in children only if prescribed by the doctor. Please consult the doctor before giving Esm-40 Tablet to children.

Esm-40 Tablet should be taken an hour before meals.

Esm-40 Tablet is usually taken on an empty stomach, first thing in the morning. If you take Esm-40 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening.

Yes, Esm-40 Tablet can be taken with domperidone if prescribed by the doctor.

Antacids can be taken along with Esm-40 Tablet if prescribed by the doctor. However, it is advised to maintain a gap of 2 hours between Esm-40 Tablet and antacid medicines.

It is advised to take Esm-40 Tablet for the duration prescribed by the doctor. Esm-40 Tablet is usually prescribed for a short term. However, it may be indicated for a long term use in cases like Zollinger-Ellison syndrome and ulcer disease.

Do not discontinue Esm-40 Tablet without consulting your doctor. To treat your condition effectively, take Esm-40 Tablet for the duration prescribed by the physician.

Esm-40 Tablet may cause weight gain in rare cases. Maintain a proper weight by eating healthy food and exercising regularly.

Yes, Esm-40 Tablet is safe to use if prescribed by the doctor.

Esm-40 Tablet can be taken with ranitidine if prescribed by the doctor. No interactions were found between both the medicines.

Drinking alcohol with Esm-40 Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So, try to avoid/limit alcohol consumption with Esm-40 Tablet .

If you miss a dose of Esm-40 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Esm-40 Tablet might cause side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen.

Consult the doctor before taking other medicines while using Esm-40 Tablet to prevent interactions. Let the doctor know if you are taking blood thinners, antifungal agents, anti-HIV drugs, anti-viral drugs, iron supplements, antibiotics, cardiac medicines and anti-cancer drugs.

Country of origin

India
Other Info - ESM0053

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Author Details

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Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 21, 2025 | 2:28 PM IST

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Reference

  1. https://www.drugs.com/mtm/esomeprazole.html
  2. https://www.nhs.uk/medicines/esomeprazole/
  3. https://www.medicines.org.uk/emc/files/pil.3002.pdf
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