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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Esiflo 125 Transhaler is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). It contains Salmeterol and Fluticasone, which relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Also, it acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Lupin Ltd

Consume Type

INHALATION

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Esiflo 125 Transhaler

Esiflo 125 Transhaler is a respiratory medication used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).

Esiflo 125 Transhaler is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take Esiflo 125 Transhaler based on your medical condition. The common side effects of Esiflo 125 Transhaler include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Esiflo 125 Transhaler do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking Esiflo 125 Transhaler. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since there are chances of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Esiflo 125 Transhaler

Treatment of Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, and Emphysema.

Medicinal Benefits

Esiflo 125 Transhaler is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Esiflo 125 Transhaler improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Esiflo 125 Transhaler is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

Directions for Use

Inhaler: Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.Rotacap/Transcap:Rotacap/Transcap is a capsule with powdered medication which is placed in Rotahaler. It is for inhalation only. Do not swallow the capsule. Rotahaler/Transhaler is a plastic inhalation device that releases the medication when you breathe. The capsule should be placed at the base of the rotahaler/transhaler and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.Respicap/Instacaps: Please read the instruction leaflet before usage and use in the dose and duration suggested by your doctor.Autohaler: Autohaler is a breath-activated device that releases the medication when you inhale. Shake the autohaler well before using it. Hold it upright and push the lever up. Place the mouthpiece in your mouth and seal your lips around it. Breathe in slowly and deeply to release the medication from the device. Hold your breath for 10 seconds and breathe out normally. Push the lever down and replace the cap.Inhalation Capsule: The capsule is meant for inhalation only; do not swallow the capsule. Check the instructions leaflet before use. Place it at the base of the inhaler and twist the mouthpiece until you hear a click sound. Breathe deeply through the mouthpiece and hold your breath for 10 seconds.Oral inhalation (Powder): Check the label for directions to use. Inhale the powder by mouth using an inhaler.Rotadisk: Rotadisk is a silver-coloured aluminium foil disk that contains four blisters to place the medication. The medicine is to be inhaled through the mouth from the Rotadisk using a plastic device called Diskhaler.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Esiflo 125 Transhaler

  • Nausea
  • Vomiting
  • Respiratory tract infection
  • Headache
  • Sore throat
  • Cough
  • Bone, muscle or joint pain
  • Increased heart rate
  • Chills
  • Black or tarry stools
  • Noisy breathing

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Esiflo 125 Transhaler, let your doctor know if have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. Esiflo 125 Transhaler causes hypokalemia (low potassium levels in the blood), therefore should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects.  Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. Esiflo 125 Transhaler can cause a rise in blood glucose levels. Hence monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Esiflo 125 Transhaler. Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

Drug Interactions

Drug-Drug Interaction: Esiflo 125 Transhaler may interact with fluid retention drugs (furosemide), corticosteroids (budesonide), bronchodilators (vilanterol, formoterol, albuterol), respiratory drugs (ipratropium), and blood pressure medicines (metoprolol).

Drug-Food Interaction: Limit alcohol intake since it may cause a rise in blood pressure leading to heart diseases. 

Drug-Disease Interaction: Let your doctor know if you have any allergic reactions to medicines, heart, liver, kidney diseases, hyperadrenocorticism, cataracts, glaucoma, hypokalaemia, fungal, bacterial, parasitic, or viral infection, and tuberculosis.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • BUDESONIDE
  • VILANTEROL
  • FORMOTEROL
  • ALBUTEROL
  • IPRATROPIUM
  • METOPROLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Esiflo 125 Transhaler.

  • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma severe.

  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.

  • Learning breathing exercises will help you move more air in and out of your lungs.

Special Advise

  • It is advised to undergo blood examination to keep a check on your potassium levels since Esiflo 125 Transhaler can cause low potassium levels in the blood (hypokalaemia).

  • Regularly monitor your blood sugar levels while using Esiflo 125 Transhaler since bronchodilators like Salmeterol can cause low blood glucose levels.

  • Consult your diabetologist if you have diabetes before using Esiflo 125 Transhaler so that your insulin or other diabetic medication can be adjusted accordingly to maintain your blood sugar levels.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may also lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Caution

Please consult your doctor if you are planning to conceive or are already pregnant before starting Esiflo 125 Transhaler.

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Breast Feeding

Caution

There is limited data on how Esiflo 125 Transhaler affects breastfeeding. Please consult your doctor before starting Esiflo 125 Transhaler.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Esiflo 125 Transhaler. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Esiflo 125 Transhaler should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Esiflo 125 Transhaler.

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Kidney

Caution

Esiflo 125 Transhaler should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Esiflo 125 Transhaler.

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Children

Caution

Esiflo 125 Transhaler is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - ESI0002

Author Details

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FAQs

Esiflo 125 Transhaler is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD).
Esiflo 125 Transhaler is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Esiflo 125 Transhaler consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways and increases airflow to the lungs. Fluticasone acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.
Esiflo 125 Transhaler should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Esiflo 125 Transhaler if you have seizures.
Esiflo 125 Transhaler contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence therapy with Esiflo 125 Transhaler is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.
Bronchodilator (Salmeterol) in Esiflo 125 Transhaler may decrease the potassium levels in your body, therefore should be used with caution. Please consult your doctor before taking Esiflo 125 Transhaler since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

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