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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:49 PM IST
Equirex Tablet is used in the treatment of peptic ulcers, irritable bowel syndrome (IBS), and enterocolitis (swelling in the intestine). It contains Chlordiazepoxide and Clidinium, which decreases stomach acid production. Also, it decreases the abnormal activity in the brain and provides a calming effect and relaxing muscles. Thus, it helps to provide relief from stomach spasms and cramps. It may cause side effects such as dry mouth, blurred vision, constipation, nausea, bloating, urination problems, drowsiness, dizziness, rash, swelling, irregular menstrual periods, and increased or decreased libido (sexual desire). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Jagsonpal Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Equirex Tablet

Equirex Tablet is used in the treatment of peptic ulcers, irritable bowel syndrome (IBS), and enterocolitis (swelling in the intestine). Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. An irritable bowel syndrome is a group of intestinal symptoms that occur together. Enterocolitis is an inflammation of the digestive tract caused by bacteria, viruses, parasites, fungi, or other causes.

Equirex Tablet is a combination of two medicines: Chlordiazepoxide and Clidinium. Chlordiazepoxide is a benzodiazepine that decreases abnormal activity in the brain. It interferes with the chemical messenger's activity that passes messages to the brain cells, providing a calming effect and relaxing muscles. Clidinium is an anticholinergic that acts by decreasing stomach acid production. It helps to provide relief from stomach spasms and cramps.

Equirex Tablet is available in the form of capsules. You should take this medicine as prescribed by your doctor. Equirex Tablet may cause side effects such as dry mouth, blurred vision, constipation, nausea, bloating, urination problems, drowsiness, dizziness, rash, swelling, irregular menstrual periods, and increased or decreased libido (sexual desire). Inform your doctor if any of these side effects persist or get worse.

Do not take Equirex Tablet if you are allergic to Chlordiazepoxide, Clidinium, or any other ingredients present in it. Before taking Equirex Tablet , inform your doctor if you have glaucoma (increased pressure inside the eye), enlarged prostate, difficulty urinating, heart problems, liver, or kidney diseases, depression, alcohol abuse, and high blood pressure. Equirex Tablet is not recommended for use in children. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Equirex Tablet

Treatment of Peptic ulcers, Irritable bowel syndrome (IBS), and Enterocolitis.

Medicinal Benefits

Equirex Tablet is a combination of two medicines: Chlordiazepoxide and Clidinium. Chlordiazepoxide is a benzodiazepine that decreases abnormal activity in the brain. It interferes with the chemical messenger's activity that passes messages to the brain cells, providing a calming effect. It can also reduce anxiety related to gastrointestinal disorders. Clidinium is an anticholinergic that acts by decreasing stomach acid production. It helps to provide relief from stomach spasms and cramps. Together, Equirex Tablet can be effectively used to treat gastrointestinal disorders such as peptic ulcers, irritable bowel syndrome (IBS), and enterocolitis (swelling in the intestine).

Directions for Use

Equirex Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Equirex Tablet

  • Dry mouth
  • Blurred vision
  • Constipation
  • Nausea
  • Bloating 
  • Urination problems
  • Drowsiness
  • Dizziness
  • Rash
  • Swelling
  • Irregular menstrual periods
  • Increased or decreased libido (sexual desire)

Drug Warnings

Equirex Tablet should be used with caution in patients with drug abuse or addiction, vision problems, or urination problems. Do not take sedatives, pain killers, cough medicines, or other medicines that cause drowsiness along with Equirex Tablet as it may cause fatal side-effects. Do not stop Equirex Tablet abruptly as it may cause withdrawal symptoms such as fits, tremors, muscle cramps, stomach cramps, depression, vomiting, sleeping problems, and sweating.

Drug Interactions

Drug-drug interactions: Equirex Tablet may interact with antacids, an anticoagulant (warfarin), antipsychotic medications (chlorpromazine, fluphenazine, and thioridazine), and antidepressants (isocarboxazid, linezolid, methylene blue, phenelzine, selegiline, and tranylcypromine).

Drug-food interactions: Avoid consumption of alcohol as it may increase drowsiness.

Drug-disease interactions: Equirex Tablet should be used with caution in patients with glaucoma (increased pressure in the eye), prostatic hypertrophy (an enlarged prostate), bladder neck obstruction (a blockage of your bladder that causes problems with urination), liver and kidney problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • THIORIDAZINE
  • ISOCARBOXAZID
  • LINEZOLID
  • METHYLENE BLUE
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption.

  • Maintain a healthy weight by regular exercising.

  • Avoid carbonated and caffeinated beverages.

  • Practice relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 

  • Avoid deep-fried and spicy foods.

  • Take foods containing probiotics as they may help in providing relief from gas and bloating.

Special Advise

  • Do not stop taking Equirex Tablet on your own, as it may cause withdrawal symptoms.
  • Equirex Tablet should be used with caution, and regular monitoring is advised in patients with glaucoma and benign prosthetic hyperplasia (BPH).

Disease/Condition Glossary

Peptic ulcers: Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods and beverages, irregular hormone levels, certain foods, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and diarrhoea.

Enterocolitis: It is an inflammation of the digestive tract caused by bacteria, viruses, parasites, fungus, or other causes. Symptoms include loss of appetite, nausea, vomiting, abdominal pain, mucous-like discharge from the rectum, and diarrhoea.

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Alcohol

Unsafe

Avoid alcohol intake as alcohol may increase drowsiness and also worsens the health condition.

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Pregnancy

Unsafe

Equirex Tablet is a category D drug. It should not be used in pregnant women as it may cause birth defects to the unborn baby.

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Breast Feeding

Caution

Equirex Tablet may decrease the production of breast milk. So, it should be used with caution in breastfeeding mothers.

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Driving

Unsafe

Equirex Tablet may cause drowsiness, so refrain from activities such as driving or operating heavy machinery.

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Liver

Caution

Equirex Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Equirex Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Equirex Tablet is not recommended for use in children under 12 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

T-210 J, Shahpur Jat, New Delhi - 110 049, India
Other Info - EQU0001

Author Details

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FAQs

Equirex Tablet is used to treat peptic ulcers, irritable bowel syndrome (IBS), and enterocolitis (swelling in the intestine).
Equirex Tablet is a combination of two drugs: Chlordiazepoxide (benzodiazepine) and Clidinium (anti-cholinergic). Chlordiazepoxide decreases abnormal activity in the brain and relaxes gastrointestinal muscles. It also reduces anxiety associated with gastrointestinal disorders. Clidinium works by reducing stomach acid and decreases stomach spasms and cramps.
Equirex Tablet should be used with caution in elderly patients as it may cause serious side-effects such as anxiety and confusion. So, it is recommended to consult a doctor before using Equirex Tablet as the dose may have to be adjusted by your doctor.
Equirex Tablet may be habit-forming, especially in people with a history of drug addiction or abuse, and in those who are alcoholics. So, before taking Equirex Tablet discuss with your doctor the possible risks associated with this medicine.
Equirex Tablet helps to treat stomach or peptic ulcers and prevent the recurrence of ulcers. It is advised to follow necessary dietary recommendations and precautions to prevent stomach ulcers.
Equirex Tablet can reduce stomach pain associated with gastrointestinal disorders such as peptic ulcers, irritable bowel syndrome, and enterocolitis. It can reduce stomach spasms and cramps.
Equirex Tablet may cause side-effects such as dry mouth, blurred vision, constipation, nausea, bloating, urination problems, drowsiness, dizziness, rash, swelling, irregular menstrual periods, and increased or decreased libido (sexual desire). Consult your doctor immediately if any of these side-effects persist or get worsen.
Equirex Tablet is contraindicated in patients who are allergic to any of its ingredients or have a history of glaucoma (an eye condition that can lead to vision loss if untreated), prostatic hypertrophy (an enlarged prostate that can cause urinary problems in men), and benign bladder neck obstruction (a condition where the bladder opening becomes narrow, making it hard to pass urine).
Yes, Equirex Tablet contains chlordiazepoxide (a benzodiazepine), which may lead to physical dependence, especially if used for a long time or misused. The benzodiazepine component has addictive potential and may cause dependence or withdrawal symptoms. Therefore, do not stop taking Equirex Tablet or reduce your dose without consulting your doctor.
Equirex Tablet should be used cautiously if you have a history of drug abuse or addiction, vision problems, or urinary issues. Avoid alcohol while using Equirex Tablet , as it may increase drowsiness. Also, you should avoid taking sedatives, painkillers, cough medicines, or any other medications that cause drowsiness along with Equirex Tablet , as this may lead to fatal side effects. Do not stop taking Equirex Tablet suddenly, as this may cause withdrawal symptoms, such as seizures, tremors, muscle cramps, stomach cramps, depression, vomiting, difficulty sleeping, and sweating. It is not recommended for use in children under 12 years old. Equirex Tablet should not be used during pregnancy, as it may cause birth defects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, before using Equirex Tablet .
An overdose of Equirex Tablet may cause symptoms such as dry mouth, blurred vision, constipation, urinating less than usual, muscle weakness, extreme drowsiness, confusion, or even loss of consciousness. In the case of an overdose, please seek emergency help immediately.
Equirex Tablet may cause sleepiness or drowsiness as a side effect. So, avoid activities like driving or operating machines after taking Equirex Tablet .
Equirex Tablet may cause constipation as a side effect. Eat fibre-rich foods and drink enough fluids to cope with constipation. If you experience severe constipation or if it does not go away, please inform your doctor.
It is not recommended to drink alcohol while taking Equirex Tablet , as it may increase the risk of side effects such as dizziness and drowsiness. It may also impair your ability to function safely, especially while driving or operating machines.
Store Equirex Tablet at room temperature, away from moisture and heat. Keep this medication out of reach of children.

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