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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
EPOTREND 2K INJECTION is used to treat anaemia due to chronic kidney disease and chemotherapy. It contains Erythropoietin alfa, human recombinant which works by stimulating the bone marrow to make more red blood cells. This medicine may sometimes cause side effects such as high blood pressure, nausea, vomiting and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Anthem Bio Pharma

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About EPOTREND 2K INJECTION

EPOTREND 2K INJECTION belongs to a class of drugs known as erythropoiesis-stimulating agent (ESA) primarily used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and anaemia due to chemotherapy (cancer treatment). Anaemia is reduced levels of haemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anaemia, which gets worse as the disease progresses. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anaemia in cancer patients.

EPOTREND 2K INJECTION contains ‘Erythropoietin alfa, human recombinant’. EPOTREND 2K INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This EPOTREND 2K INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

EPOTREND 2K INJECTION will be administered by a healthcare professional; do not self-administer. You may experience high blood pressure, nausea, vomiting and fever. Most of these side effects of EPOTREND 2K INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to EPOTREND 2K INJECTION or any other medicines, please tell your doctor. EPOTREND 2K INJECTION should not be taken in conditions like heart disease, high blood pressure, or liver disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using EPOTREND 2K INJECTION . EPOTREND 2K INJECTION may affect your ability to drive and use machines as EPOTREND 2K INJECTION may cause fits disorder during the first 90 days of treatment. 

Uses of EPOTREND 2K INJECTION

Treatment of Anemia due to chronic kidney disease, Anemia due to chemotherapy.

Directions for Use

EPOTREND 2K INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

EPOTREND 2K INJECTION helps in the treatment of anemia which may happen due to chronic kidney disease and cancer chemotherapy. EPOTREND 2K INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This EPOTREND 2K INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood). Besides this EPOTREND 2K INJECTION is also used for the treatment of anemia caused by a medicine known as zidovudine for the treatment of HIV (human immunodeficiency viruses). EPOTREND 2K INJECTION  also decreases the requirement for blood cell transfusions.

How EPOTREND 2K INJECTION Works

EPOTREND 2K INJECTION contains ‘Erythropoietin alfa, human recombinant’. EPOTREND 2K INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This EPOTREND 2K INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

Storage

Store in a cool and dry place away from sunlight

Side Effects of EPOTREND 2K INJECTION

  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Joint pain
  • Clotting at the injection site

What if I have taken an overdose of EPOTREND 2K INJECTION

Since EPOTREND 2K INJECTION is administered by a healthcare professional, an overdose is unlikely to occur. Signs and symptoms of overdose may include excessive and/or rapid increase in haemoglobin concentration and cardiovascular events. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are known to be allergic to EPOTREND 2K INJECTION or any other medicines, please tell your doctor. EPOTREND 2K INJECTION should not be taken in conditions like high blood pressure, heart disease, heart attack, blood clot in the brain (stroke), fits disorder, liver disease, or kidney disease. Before taking EPOTREND 2K INJECTION inform your doctor if you have any type of cancer or skin reactions. If you are pregnant or a nursing mother, it is advised to consult a doctor before using EPOTREND 2K INJECTION . EPOTREND 2K INJECTION may affect your ability to drive and using machines as EPOTREND 2K INJECTION may cause fits to disorder during the first 90 days of treatment. EPOTREND 2K INJECTION should not be used for children below 1 month of age during treatment of anemia due to chronic kidney disease. EPOTREND 2K INJECTION should not be used for children below 5 years of age during treatment of anemia due to chemotherapy.

Drug-Drug Interactions

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ErythropoietinLenalidomide
Severe
ErythropoietinPomalidomide
Severe

Drug-Drug Interactions

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ErythropoietinLenalidomide
Severe
How does the drug interact with Epotrend 2k Injection:
Combining Epotrend 2k Injection with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Epotrend 2k Injection and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Epotrend 2k Injection:
Pomalidomide can cause serious blood clots and taking it alongside Epotrend 2k Injection may enhance the risk.

How to manage the interaction:
Co-administration of Epotrend 2k Injection with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Epotrend 2k Injection:
Carfilzomib can cause serious blood clots and taking it alongside Epotrend 2k Injection may enhance the risk.

How to manage the interaction:
Co-administration of Epotrend 2k Injection with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinThalidomide
Severe
How does the drug interact with Epotrend 2k Injection:
Taking thalidomide with Epotrend 2k Injection may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Epotrend 2k Injection and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Your doctor may get your blood tests done frequently to examine the levels of blood cells, hemoglobin, and electrolytes such as potassium in your blood.
  • Eat food that is rich in iron, vitamin B12, and folic acid.
  • Eat food like leafy, green vegetables, fish, eggs, and liver.
  • Do mild to moderate exercise.

Habit Forming

No

Therapeutic Class

ERYTHROPOIESIS STIMULATING AGENTS (ESAs)

EPOTREND 2K INJECTION Substitute

Substitutes safety advice
  • EPOFIT 2000I.U PREFILLED SYRINGES

    by Others

    607.86per tablet
  • EPOFER 2000IU INJECTION

    by Others

    531.00per tablet
  • RPO 2000IU INJECTION PFS 1ML

    by Others

    558.80per tablet
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Alcohol

Caution

It is not known that EPOTREND 2K INJECTION may interact with alcohol. Therefore, avoid drinking alcohol while using EPOTREND 2K INJECTION .

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Pregnancy

Caution

EPOTREND 2K INJECTION should not be taken until prescribed. Your doctor will decide what is the best treatment for you. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking EPOTREND 2K INJECTION . Your doctor will advise you to either stop or continue treatment.

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Driving

Caution

EPOTREND 2K INJECTION may affect your ability to drive and using machines as EPOTREND 2K INJECTION may cause fits to disorder during the first 90 days of treatment.

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Liver

Caution

Take EPOTREND 2K INJECTION with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

EPOTREND 2K INJECTION is safely given to the kidney patients only if prescribed by your doctor.

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Children

Caution

EPOTREND 2K INJECTION should be used in children only when prescribed by a doctor.

FAQs

EPOTREND 2K INJECTION is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and chemotherapy (cancer treatment).

Yes, EPOTREND 2K INJECTION can be used for children above 1 month of age during treatment of anemia due to chronic kidney disease. EPOTREND 2K INJECTION can be used for children above 5 years of age during treatment of anemia due to chemotherapy. The effectiveness of EPOTREND 2K INJECTION and side effects observed in children is the same as adults, and used only when prescribed by a doctor.

Yes, EPOTREND 2K INJECTION may increase the blood pressure. During initial treatment with EPOTREND 2K INJECTION , blood pressure should be examined and those who have high blood pressure should take proper methods to regulate blood pressure. Your doctor may stop EPOTREND 2K INJECTION if the blood pressure continues uncontrolled.

EPOTREND 2K INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This EPOTREND 2K INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood).

The most common side effects of EPOTREND 2K INJECTION are high blood pressure, nausea, vomiting, and fever, diarrhea, feeling upset in the stomach, skin rashes, stuffy nose, sore throat, bone, or muscle pain. Most of these side effects of EPOTREND 2K INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.
Other Info - EPO0063

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