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Reviewed By Santoshini Reddy G , M Pharmacy

Epival Syrup is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It contains Sodium valproate, which decreases the excessive and abnormal nerve activity in the brain. Thereby, helps in controlling seizures. It helps block the nerve transmission across the brain and provides a calming effect. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, changes in appetite, weight changes, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Epival Syrup

Epival Syrup is used to treat epilepsy/seizures/fits. Additionally, Epival Syrup is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Epival Syrup contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. Epival Syrup increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby, helps treat bipolar disorder.

You are advised to take Epival Syrup for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, diarrhoea, and changes in weight/appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Epival Syrup without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first period whilst on treatment with Epival Syrup . Do not take Epival Syrup if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Epival Syrup . Consult your doctor before taking Epival Syrup if you are breastfeeding. Do not drive or operate machinery as Epival Syrup may cause drowsiness and dizziness. Avoid consuming alcohol along with Epival Syrup as it could lead to increased dizziness and sleepiness.

Uses of Epival Syrup

Epival Syrup is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Epival Syrup are as follows:
• Seizure Management: Epival Syrup is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.
• Bipolar Disorder Treatment: Epival Syrup can be used in the treatment of bipolar disorder, aiding in mood stabilization and reducing the frequency of mood swings.
• Migraine Prevention: Epival Syrup may also be prescribed to prevent migraines, providing relief from recurrent headaches.

Directions for Use

  • Epival Syrup can be taken with food to prevent stomach upset or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Take the prescribed dose by mouth using the measuring cup, dosing syringe, or dropper.
  • Shake the bottle well before use.

Medicinal Benefits

Epival Syrup belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Epival Syrup is also used to treat bipolar disorder and prevent migraine headaches. Epival Syrup decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Epival Syrup is used to treat both localised (seizures which affect only a part of the brain) and generalised seizures (seizures which affect the entire brain).

How Epival Syrup Works

Epival Syrup contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. Epival Syrup increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby, it helps treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Epival Syrup

Do not take more than the prescribed dose of Epival Syrup as it may cause an overdose. The symptoms of overdose include headache, dizziness, confusion, memory loss, tiredness, feeling sick or being sick, blurred vision due to pupil of the eye becoming smaller, poor reflexes, weak or floppy muscles, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing, shortness of breath or chest pain. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Epival Syrup if you are allergic to any of its contents; if you have liver problems, severe hepatitis, urea cycle disorders, porphyria, or an inborn deficiency of carnitine. Consult your doctor immediately if you experience suicidal tendencies while taking Epival Syrup . Contact your doctor if your child gets her first period during the treatment with Epival Syrup . Do not take Epival Syrup if you are pregnant unless prescribed by the doctor, as it is a pregnancy category D medicine and can cause serious congenital disabilities. Consult your doctor before taking Epival Syrup if you are breastfeeding. Epival Syrup may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Epival Syrup as it could lead to increased dizziness and sleepiness.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Epival Syrup 200 ml:
Combining Sodium phenylbutyrate and Epival Syrup 200 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Epival Syrup 200 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epival Syrup 200 ml:
The combined use of Ertapenem and Epival Syrup 200 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Ketamine and Epival Syrup 200 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Epival Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Teriflunomide and Epival Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Epival Syrup 200 ml:
Using buprenorphine together with Epival Syrup 200 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Epival Syrup 200 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Vorinostat with Epival Syrup 200 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Epival Syrup 200 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Epival Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Leflunomide and Epival Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Epival Syrup 200 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Lithium with Epival Syrup 200 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Epival Syrup 200 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Epival Syrup 200 ml:
Co-administration of Meropenam and Epival Syrup 200 ml together can reduce the effect of Epival Syrup 200 ml.

How to manage the interaction:
Co-administration of Meropenam and Epival Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Epival Syrup as it may cause increased dizziness and sleepiness.

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Pregnancy

Unsafe

Epival Syrup belongs to pregnancy category D. Avoid taking Epival Syrup if you are pregnant, as it could lead to serious birth defects.

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Breast Feeding

Caution

Epival Syrup may pass into breastmilk. Consult your doctor before taking Epival Syrup if you are breastfeeding.

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Driving

Unsafe

Epival Syrup causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Epival Syrup should not be used if you have liver disease or severe hepatitis. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Epival Syrup can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Have a query?

FAQs

Epival Syrup is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).

Epival Syrup decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messengers and prevents overactivity of the brain, thereby controlling seizure episodes.

Epival Syrup limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition characterised by intense headaches.

Do not discontinue Epival Syrup without consulting your doctor. To treat your condition effectually, continue taking Epival Syrup for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Epival Syrup ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Epival Syrup works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Epival Syrup may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Epival Syrup may cause side effects like stomach pain, nausea, vomiting, diarrhoea, and changes in weight/appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Yes, Epival Syrup causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

Epival Syrup may change levels of liver enzymes, blood clotting factors, salts or sugars shown up on blood and urine tests. Hence, if you are undergoing any tests, inform the doctor that you are taking Epival Syrup .

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - EPI0011

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