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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Epineph Injection 1 ml is used to treat cardiac arrest, hypotension due to septic shock and life-threatening allergic reactions. It contains Adrenaline which improves blood flow, relaxes the muscles, and increases mean arterial blood pressure. In some cases, this medicine may cause side effects such as difficulty breathing, blurred vision, headache, dizziness, mood or mental changes, and an increase in blood pressure. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ADRENALINE-1MG

Manufacturer/Marketer :

Themis Chemicals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Epineph Injection 1 ml

Epineph Injection 1 ml belongs to a class of medicines called 'sympathomimetic', primarily used for the treatment of cardiac arrest, hypotension due to septic shock and life-threatening allergic reactions. Cardiac arrest is a sudden loss of blood flow resulting from the failure of the heart to pump effectively. Severe allergic reactions, including anaphylaxis due to foods, drugs, insect stings, bites, or other allergens. It may cause symptoms like breathing difficulty, facial swelling, dizziness, confusion and hives.

Epineph Injection 1 ml contains 'adrenaline', also called epinephrine. Epineph Injection 1 ml is used to increase blood flow to the heart and increase the chance of restoring a heartbeat in cardiac arrest. Epineph Injection 1 ml increases mean arterial blood pressure in adult patients with hypotension associated with septic shock. It is also used to increase blood flow through veins by constricting blood vessels and helps to relax the muscles, which block the airways and allow breathing to return to normal in allergic reactions due to foods, drugs, insect stings or bites or any other allergens.

Epineph Injection 1 ml is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Epineph Injection 1 ml may cause common side effects like increased heart rate, difficulty breathing, blurred vision, headache, dizziness, mood or mental changes, and an increase in blood pressure. If these side effects persist, consult your doctor immediately.

Epineph Injection 1 ml should not be taken if you are allergic to it. Inform your doctor if you are using any medicines other than Epineph Injection 1 ml. Inform your doctor if you are a pregnant/breastfeeding woman. Do not use Epineph Injection 1 ml if the solution is discoloured. Epineph Injection 1 ml should be used with caution in brain disorders, pheochromocytoma (tumour on adrenal gland), pulmonary oedema, kidney impairment, liver impairment, hypertension, hyperthyroidism, diabetes mellitus, and narrow-angle glaucoma.

Uses of Epineph Injection 1 ml

Treatment of Cardiac arrest, Hypotension due to septic shock and life-threatening allergic reactions.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Epineph Injection 1 ml contains 'adrenaline'; it is also called epinephrine. It belongs to a class of medicines called 'sympathomimetic', primarily taken for the treatment of cardiac arrest, hypotension due to septic shock and life-threatening allergic reactions. Epineph Injection 1 ml works by increasing blood flow to the heart and also increases the chance of restoring a heartbeat in cardiac arrest. Epineph Injection 1 ml increases mean arterial blood pressure in adult patients with hypotension associated with septic shock. It is also used to increase blood flow through veins by constricting blood vessels and helps to relax the muscles, which block the airways and allow breathing to return to normal in allergic reactions due to foods, drugs, insect stings or bites or any other allergens. Epineph Injection 1 ml is also used in the treatment of bradycardia(slow heart rate), mydriasis( dilation of the pupil of the eye) and acute asthma.

How Epineph Injection 1 ml Works

Epineph Injection 1 ml contains 'adrenaline', also called epinephrine. Epineph Injection 1 ml is used to increase blood flow to the heart and increase the chance of restoring a heartbeat in cardiac arrest. Epineph Injection 1 ml increases mean arterial blood pressure in adult patients with hypotension associated with septic shock. It is also used to increase blood flow through veins by constricting blood vessels and helps to relax the muscles, which block the airways and allow breathing to return to normal in allergic reactions due to foods, drugs, insect stings or bites or any other allergens.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epineph Injection 1 ml

  • Increased heart rate
  • Difficulty in breathing
  • Blurred vision
  • Headache
  • Dizziness
  • Mood or mental changes
  • Increase in blood pressure.

What if I have taken an overdose of Epineph Injection 1 ml

Since Epineph Injection 1 ml is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Epineph Injection 1 ml should not be taken if you are allergic to it. Inform your doctor if you are using any medicines other than Epineph Injection 1 ml. Inform your doctor if you are a pregnant/breastfeeding woman. Epineph Injection 1 ml should be used with caution in brain disorders, pheochromocytoma (tumour on adrenal gland), pulmonary oedema, kidney impairment, hypertension, and liver impairment. Epineph Injection 1 ml is not recommended for diabetes, Parkinson's disease, hyperthyroidism, narrow-angle glaucoma and cardiovascular diseases. Epineph Injection 1 ml is for emergency use only, and medical supervision of the patients is necessary after administration.

Drug-Drug Interactions

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EpinephrineLinezolid
Critical
EpinephrineDihydroergotamine
Critical

Drug-Drug Interactions

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EpinephrineLinezolid
Critical
How does the drug interact with Epineph Injection 1 ml:
Taking Linezolid with Epineph Injection 1 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Linezolid with Epineph Injection 1 ml is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineDihydroergotamine
Critical
How does the drug interact with Epineph Injection 1 ml:
When Dihydroergotamine is taken with Epineph Injection 1 ml, the amount of Dihydroergotamine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dihydroergotamine with Epineph Injection 1 ml is not recommended as it can lead to an interaction. It should be taken only if your doctor has advised it. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion, or slurred speech contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineTranylcypromine
Critical
How does the drug interact with Epineph Injection 1 ml:
Coadministration of Epineph Injection 1 ml with Tranylcypromine can increase the risk or severity of high blood pressure or increased heart rate.

How to manage the interaction:
Taking Epineph Injection 1 ml with Tranylcypromine is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineDoxepin
Severe
How does the drug interact with Epineph Injection 1 ml:
Coadministration of Doxepin with Epineph Injection 1 ml can enhance the effects of Epineph Injection 1 ml on blood pressure.

How to manage the interaction:
Although there is a possible interaction between Doxepin and Epineph Injection 1 ml, you can take these medicines together if prescribed by your doctor. It's important to monitor your blood pressure regularly. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, throbbing headache, tremor, or palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineImipramine
Severe
How does the drug interact with Epineph Injection 1 ml:
Coadministration of Epineph Injection 1 ml and Imipramine can increase the risk or severity of high blood pressure.

How to manage the interaction:
Although taking Epineph Injection 1 ml and Imipramine together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to monitor your blood pressure regularly. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, throbbing headache, tremor, or palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineNortriptyline
Severe
How does the drug interact with Epineph Injection 1 ml:
Taking Epineph Injection 1 ml with Nortriptyline can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Epineph Injection 1 ml with Nortriptyline together can result in an interaction, but it can be taken only if your doctor has advised it. It's important to monitor your blood pressure regularly. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineSotalol
Severe
How does the drug interact with Epineph Injection 1 ml:
Coadministration of Epineph Injection 1 ml with Sotalol may reduce the effects of Epineph Injection 1 ml. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Epineph Injection 1 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EpinephrinePropranolol
Severe
How does the drug interact with Epineph Injection 1 ml:
Co-administration of Epineph Injection 1 ml with Propranolol may cause severe high blood pressure and reduced heart rate.

How to manage the interaction:
Taking Epineph Injection 1 ml with Propranolol can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
EpinephrineLabetalol
Severe
How does the drug interact with Epineph Injection 1 ml:
Taking Labetalol along with Epineph Injection 1 ml can reduce the effects of Epineph Injection 1 ml.

How to manage the interaction:
Taking Labetalol and Epineph Injection 1 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpinephrineFormoterol
Severe
How does the drug interact with Epineph Injection 1 ml:
Using Epineph Injection 1 ml together with formoterol may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Formoterol and Epineph Injection 1 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat fresh vegetables, nuts, beans and legumes.
  • Avoid alcohol
  • Quit smoking.
  • Avoid fatty foods and spicy foods.
  • Do regular exercise/walking to maintain good health.
  • Keep your surroundings clean and neat to avoid sting/insect bites.
  • Avoid contaminating your food in case of food allergies.

Habit Forming

No

Therapeutic Class

SYMPATHOMIMETICS

Epineph Injection 1 ml Substitute

Substitutes safety advice
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    12.20per tablet
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    122.90per tablet
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  • Adrenaline Tartrate Injection 1 ml (Rathi Lab)

    13.05per tablet
  • Adroglare Injection 1 ml

    by AYUR

    12.20per tablet
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Alcohol

Caution

Avoid or limit consumption of alcohol while on treatment with Epineph Injection 1 ml.

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Pregnancy

Caution

Epineph Injection 1 ml is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

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Breast Feeding

Caution

Epineph Injection 1 ml is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

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Driving

Caution

After receiving this medicine, do not drive or operate machines which need high concentration as it may cause dizziness.

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Liver

Caution

Epineph Injection 1 ml should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Depending on the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required.

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Kidney

Caution

Epineph Injection 1 ml should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

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Children

Caution

Epineph Injection 1 ml may be used in children, but dose adjustments should be made by the doctor based on the height and weight of the child. So please consult your doctor.

FAQs

Epineph Injection 1 ml is used to treat cardiac arrest, hypotension due to septic shock and life-threatening allergic reactions.
Epineph Injection 1 ml is used to increase blood flow to the heart and increase the chance of restoring a heartbeat in cardiac arrest. Epineph Injection 1 ml increases mean arterial blood pressure in adult patients with hypotension associated with septic shock. It is also used to increase blood flow through veins by constricting blood vessels and helps to relax the muscles, which block the airways and allow breathing to return to normal in allergic reactions due to foods, drugs, insect stings or bites or any other allergens.
Epineph Injection 1 ml is not recommended in thyrotoxicosis and narrow-angle glaucoma. It may worsen the patient's condition.
Epineph Injection 1 ml should be used with extreme caution in patients with brain damage or brain disorders such as stroke due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Epineph Injection 1 ml will be administered into a muscle (intramuscular - IM) by the doctor or nurse. However, in emergency situations, the doctor may give you a diluted injection into a vein (intravenous - IV). Do not self-administer Epineph Injection 1 ml.
Epineph Injection 1 ml should not be given in areas like your fingers, ears, toes, nose, genital area, or buttocks, as these areas may not have poor blood circulation. If repeated doses are needed, the doctor will choose a different injection site.
Do not be given Epineph Injection 1 ml if the solution is discoloured and if you are allergic to any of its ingredients.
If you experience any difficulty in breathing, sudden wheeziness, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body), consult the doctor immediately.
The side effects of Epineph Injection 1 ml include blurred vision, headache, dizziness, mood or mental changes, difficulty in breathing, increased heart rate and increase in blood pressure. Consult the doctor if any of these side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - EPI0314

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