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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Eparel 50 mg Tablet is used to treat diabetic neuropathy (diabetic nerve pain). It contains Epalrestat which prevents the accumulation of sorbitol that leads to nerve pain. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

EPALRESTAT-50MG

Manufacturer/Marketer

Micro Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Eparel 50 mg Tablet

Eparel 50 mg Tablet is used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Eparel 50 mg Tablet contains ‘Epalrestat’ that works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Eparel 50 mg Tablet prevents the accumulation of sorbitol. Thus, it helps in treating diabetic neuropathy.

Take Eparel 50 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Eparel 50 mg Tablet if you are pregnant or breastfeeding. Eparel 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Eparel 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Eparel 50 mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Eparel 50 mg Tablet

Treatment of Diabetic neuropathy (diabetic nerve pain).

Medicinal Benefits

Eparel 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors. Eparel 50 mg Tablet is used to manage diabetic neuropathy. Eparel 50 mg Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes, which leads to nerve pain. Eparel 50 mg Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

Directions for Use

Swallow Eparel 50 mg Tablet as a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eparel 50 mg Tablet

  • Dizziness
  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea

Drug Warnings

Do not take Eparel 50 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Eparel 50 mg Tablet if you are pregnant or breastfeeding. Eparel 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Eparel 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Eparel 50 mg Tablet as it could lead to increased drowsiness and sleepiness.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.

  • Include cayenne pepper in your diet as it can help lower neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. If you have diabetes and experience numbness, pain, tingling sensation, or weakness in the hands or legs, you must consult a doctor. The pain could be intermittent or continuous, and it is felt as a prickling, stabbing, tingling, or burning sensation. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Eparel 50 mg Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the use of Eparel 50 mg Tablet in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the use of Eparel 50 mg Tablet in breastfeeding women. Consult your doctor before taking Eparel 50 mg Tablet ; your doctor will decide whether Eparel 50 mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Eparel 50 mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Eparel 50 mg Tablet should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Eparel 50 mg Tablet should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Eparel 50 mg Tablet should not be given to children as safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - EPA0001

Author Details

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FAQs

Eparel 50 mg Tablet is used to manage diabetic neuropathy, a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients.
Eparel 50 mg Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Eparel 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.
Diarrhoea could be a side-effect of Eparel 50 mg Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.
Eparel 50 mg Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Eparel 50 mg Tablet . Regularly monitor blood pressure levels while taking Eparel 50 mg Tablet .
Do not discontinue Eparel 50 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Eparel 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Eparel 50 mg Tablet .
Eparel 50 mg Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

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