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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Enzoflam Tablet is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. It reduces mild to moderate pain, inflammation and fever decreasing swelling at the painful site. It may cause common side effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Enzoflam Tablet

Enzoflam Tablet is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints, which causes pain and joint stiffness.

Enzoflam Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking the COX enzyme's effect, fewer prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent, thereby decreasing swelling at the painful site. 
 
You are advised to take Enzoflam Tablet for as long as your doctor has prescribed it for you. In some cases, Enzoflam Tablet may cause certain common side effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Enzoflam Tablet may cause drowsiness and dizziness, so drive with caution. Enzoflam Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Enzoflam Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Enzoflam Tablet

Treatment of Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Directions for Use

Take Enzoflam Tablet with food. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Enzoflam Tablet is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Enzoflam Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Enzoflam Tablet increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reducing inflammation. 

How Enzoflam Tablet Works

Enzoflam Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking the COX enzyme's effect, fewer prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent, thereby decreasing swelling at the painful site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enzoflam Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

What if I have taken an overdose of Enzoflam Tablet

Do not take more than the prescribed dose of Enzoflam Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Enzoflam Tablet if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Enzoflam Tablet may cause drowsiness and dizziness, so drive only if you are alert. Enzoflam Tablet is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Enzoflam Tablet as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Enzoflam Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Enzoflam Tablet unless prescribed.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ParacetamolLomitapide
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Enzoflam Tablet 10's with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Enzoflam Tablet 10's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ParacetamolLomitapide
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Lomitapide and Enzoflam Tablet 10's may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Enzoflam Tablet 10's and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Enzoflam Tablet 10's and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Enzoflam Tablet 10's and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Enzoflam Tablet 10's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Enzoflam Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Enzoflam Tablet 10's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Enzoflam Tablet 10's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of ketamine and Enzoflam Tablet 10's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Enzoflam Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Teriflunomide with Enzoflam Tablet 10's may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Enzoflam Tablet 10's with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Mipomersen with Enzoflam Tablet 10's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Enzoflam Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Enzoflam Tablet 10's:
Co-administration of Enzoflam Tablet 10's and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Enzoflam Tablet 10's and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Enzoflam Tablet 10's:
Coadministration of Enzoflam Tablet 10's with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflam Tablet 10's and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes; instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.

  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Enzoflam Tablet Substitute

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Enzoflam Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Enzoflam Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Enzoflam Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Enzoflam Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Enzoflam Tablet should not be given to children less than 10 years of age, as the safety and effectiveness have not been established.

FAQs

Enzoflam Tablet is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches.
Enzoflam Tablet contains Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase is a protein enzyme that helps break down and dissolves the abnormal proteins at the inflammation site, thereby reducing pain.
Enzoflam Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
Diarrhoea might be a side-effect of Enzoflam Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Enzoflam Tablet should not be taken for longer durations unless prescribed by the doctor. If Enzoflam Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.
Avoid taking Enzoflam Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.
No, you should not use the Enzoflam Tablet if you have stomach ulcers. Enzoflam Tablet can irritate the stomach lining, worsen existing stomach ulcers, or even cause new ones to develop. If you have stomach ulcers, it's essential to consult with your doctor to discuss appropriate treatment options.
No, Enzoflam Tablet is not a muscle relaxant.
The amount and frequency of your medication can vary depending on your health, age, and other medications you're taking. Always follow your healthcare professional's directions to use this medicine safely and correctly.
Yes, Enzoflam Tablet contains diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID).
Store in a cool and dry place away from sunlight. Keep Enzoflam Tablet out of the sight and reach of children.
Enzoflam Tablet can be safe when used as directed by a healthcare professional. However, like all medications, it has potential side effects and may interact with other medicines. It's important to consult with a doctor or pharmacist before starting or continuing to use this medication. They can assess your health situation and determine if it suits you.
Even if the pain is alleviated, this does not necessarily imply that the underlying condition has healed completely. Stopping the medicine prematurely may result in a return of your symptoms.
Yes, Enzoflam Tablet can cause nausea and vomiting. These are common side effects of the medication, especially when taken on an empty stomach or in high doses. If nausea or vomiting is persistent or severe, it's important to seek medical attention.
Yes, Enzoflam Tablet can cause dizziness. It is a common side effect of the medication, especially when starting the medication or taking a higher dose. If dizziness is persistent or severe, seeking medical attention is essential.
It is generally safe to use Enzoflam Tablet with Vitamin B-Complex. However, you should always discuss with your doctor or pharmacist before combining any medications, especially if you have underlying health concerns or are taking other prescriptions. They can evaluate potential interactions and confirm that the combination is safe for you.
No, you should not take Enzoflam Tablet for stomach pain. If you have stomach pain, you should consult a doctor to find out what's causing it and get the right therapy.
Yes, the use of Enzoflam Tablet may cause damage to the kidneys. This may occur in some people, especially those at risk for kidney problems. If you are concerned about your risk of kidney damage while taking Enzoflam Tablet , it's essential to talk to your doctor. They can monitor your kidney function, adjust your dosage, or recommend alternative medications if necessary.
Use of Enzoflam Tablet during pregnancy is not advised unless prescribed by a doctor. Please consult your doctor if you are pregnant; your doctor will prescribe Enzoflam Tablet only if the benefits outweigh the risks.
Common side effects of Enzoflam Tablet may cause nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Enzoflam Tablet may be unsafe for some people based on their medical condition. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Enzoflam Tablet may interact with various medications. So, seek personalized medical guidance from your healthcare professional by knowing about all your medications.
Store in a cool and dry place away from sunlight. Keep Enzoflam Tablet out of reach and out of sight to children.
Taking Enzoflam Tablet with food is generally recommended to reduce the risk of stomach upset.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ENZ0002

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