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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Endofit Tablet is used to treat endometriosis. It contains Dienogest which suppresses the production of a hormone (oestradiol) that causes excess growth in the endometrium. In some cases, this medicine may cause side effects such as acne, headache, abdominal pain, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition :

DIENOGEST-2MG

Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Endofit Tablet is used for the management of painful symptoms of endometriosis. Endometriosis is a painful disorder in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus. Endometriosis generally involves ovaries, pelvis lining, and fallopian tubes.
 
Endofit Tablet contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Endofit Tablet helps in treating pelvic pain associated with endometriosis.
 
You are advised to take Endofit Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Endofit Tablet may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid taking Endofit Tablet if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Endofit Tablet . Endofit Tablet should not be given to children who have not had their first period. Endofit Tablet may cause dizziness, so drive with caution. Avoid or limit alcohol consumption, as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Treatment of Endometriosis
Swallow the medicine as a whole with water; do not chew, break it.

Endofit Tablet belongs to a group of medicines called progestin indicated for the management of endometriosis. Endofit Tablet suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Endofit Tablet helps in treating pelvic pain associated with endometriosis. Endofit Tablet may also be used in menopausal hormonal therapy and heavy periods.

Endofit Tablet contains ‘Dienogest’, which suppresses the production of a hormone called estradiol, which causes excess growth in the endometrium. Thereby, Endofit Tablet helps in treating pelvic pain associated with endometriosis.
Store in a cool and dry place away from sunlight
  • Acne
  • Headache
  • Depression
  • Breast discomfort
  • Nausea
  • Vomiting
  • Abdominal pain
Take Endofit Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Do not take Endofit Tablet if you are allergic to any of its components; if you have a blood clot in the lungs, heart, brain, blood vessels of legs or any part of the body, if you have/had diabetes mellitus with damaged blood vessel, severe liver damage, unexplained vaginal bleeding, and benign or malignant tumour. Talk to your doctor if you have diabetes, high blood pressure, depression, are overweight, have chloasma (yellowish-brown pigmentation on the skin), had an ectopic pregnancy (embryo develops outside the womb), or if you or anyone in your immediate family has had blood clots in lungs/legs, or heart attack, high cholesterol or stroke. Avoid taking Endofit Tablet if you are pregnant, planning for pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking Endofit Tablet . Endofit Tablet should not be given to children who have not had their first period. Endofit Tablet may cause dizziness, so drive with caution.

verifiedApollotooltip
DienogestEfavirenz
Critical
DienogestPhenytoin
Severe

Drug-Drug Interactions

DienogestEfavirenz
Critical
How does the drug interact with Endofit Tablet 10's:
When Efavirenz is taken with Endofit Tablet 10's, it can lower the metabolism of Endofit Tablet 10's and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Endofit Tablet 10's can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
DienogestPhenytoin
Severe
How does the drug interact with Endofit Tablet 10's:
Taking Phenytoin with Endofit Tablet 10's may reduce the blood levels and effects of Endofit Tablet 10's.

How to manage the interaction:
Although taking Phenytoin and Endofit Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. If you use Endofit Tablet 10's as hormone replacement therapy for menopause, let a doctor know if your symptoms stop being controlled by your medication or if you start bleeding abnormally. Do not discontinue any medications without consulting a doctor.
DienogestDantrolene
Severe
How does the drug interact with Endofit Tablet 10's:
Co-administration of Dantrolene with Endofit Tablet 10's can cause serious side effects that may affect your liver.

How to manage the interaction:
Taking Endofit Tablet 10's with Dantrolene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DienogestCarbamazepine
Severe
How does the drug interact with Endofit Tablet 10's:
Taking carbamazepine with Endofit Tablet 10's may increase the effect of carbamazepine.

How to manage the interaction:
Although there is a possible interaction, Endofit Tablet 10's can be taken with Carbamazepine if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
DienogestMycophenolic acid
Severe
How does the drug interact with Endofit Tablet 10's:
Co-administration of Endofit Tablet 10's with Mycophenolic acid may decrease the levels and action of Endofit Tablet 10's.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Endofit Tablet 10's, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
DienogestPrimidone
Severe
How does the drug interact with Endofit Tablet 10's:
Taking Endofit Tablet 10's with Primidone may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between primidone and Endofit Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DienogestBosentan
Severe
How does the drug interact with Endofit Tablet 10's:
Co-administration of Endofit Tablet 10's with Bosentan may decrease the effectiveness of Endofit Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Endofit Tablet 10's can be taken with Bosentan if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DienogestFosphenytoin
Severe
How does the drug interact with Endofit Tablet 10's:
When Endofit Tablet 10's is taken with Fosphenytoin, it can increase the risk of severe bleeding.

How to manage the interaction:
Although taking Endofit Tablet 10's and Fosphenytoin together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like unusual bleeding, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
verifiedApollotooltip
DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

DIENOGEST-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Endofit Tablet 10's with Grapefruit and Grapefruit juice may increase the side effects of Endofit Tablet 10's. Consuming Grapefruit and grapefruit juice should be avoided while taking Endofit Tablet 10's.
  • Include diet-fibrous foods, iron-rich foods, foods rich in essential fatty acids, and anti-oxidant rich food.

  • Maintain a healthy diet and exercise regularly.

  • Practice meditation and yoga. Acupuncture and massages can also be helpful.

  • Avoid or limit caffeine intake.

No
PROGESTIN

Endofit Tablet Substitute

Substitutes safety advice
  • Visanne Tablet 28's

    by AYUR

    116.12per tablet
  • Dinogest Tablet 10's

    by AYUR

    54.23per tablet
  • Endoreg Tablet 14's

    by AYUR

    56.31per tablet
  • Emersa Tablet 10's

    by AYUR

    58.77per tablet
  • Dinofirst Tablet 15's

    55.44per tablet
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Unsafe

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Unsafe

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FAQs

Endofit Tablet is indicated for the management of painful symptoms of endometriosis, a condition in which the tissue that generally lines the endometrium (inside the uterus) grows outside the uterus.
Endofit Tablet suppresses the production of a hormone called estradiol which causes excess growth of the endometrium. Thereby, Endofit Tablet helps in treating pelvic pain associated with endometriosis.
Endofit Tablet may cause weight gain. Maintain a healthy weight by exercising regularly. Try eating smaller but more frequent meals. Consult your doctor if you notice severe weight gain.
Do not stop taking Endofit Tablet on your own. Continue taking Endofit Tablet for as long as your doctor has prescribed it for you depending on your condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Endofit Tablet .
Avoid using hormonal contraceptives with Endofit Tablet ; instead, use non-hormonal contraceptive methods such as condoms or barrier methods. Please consult your doctor; he/she may advise regarding proper contraception.
Antibiotics and antifungal medicines might affect how Endofit Tablet works or might be affected by Endofit Tablet . Therefore, consult your doctor before taking antibiotics or antifungals with Endofit Tablet .
Endofit Tablet may cause irregular menstrual bleeding or infrequent periods. Talk to your doctor if you experience this.
Long term use of Endofit Tablet might lower bone mineral density and affect bone health. An adequate intake of calcium and vitamin D either via your food or supplements may be helpful.
Endofit Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of treatment based on your condition.
Endofit Tablet should be swallowed as a whole with water; do not crush or chew it.
Endofit Tablet contains dienogest, which belongs to a group of medicines called progestin and is indicated for the management of endometriosis.
Yes, Endofit Tablet is a synthetic steroid.
Endofit Tablet helps endometriosis by suppressing the production of a hormone called estradiol, which causes excess growth in the endometrium.
Endofit Tablet may cause side effects such as acne, headache, depression, breast discomfort, abdominal pain, nausea, and vomiting. Talk to your doctor if any of the side effects persist or worsen.
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