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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Encrpc 40mg Capsule is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Composition :

ENZALUTAMIDE-40MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Encrpc 40mg Capsule

Encrpc 40mg Capsule belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Encrpc 40mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Encrpc 40mg Capsule must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Encrpc 40mg Capsule may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Encrpc 40mg Capsule use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Encrpc 40mg Capsule

Treatment of Prostate Cancer

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush or chew it.

Solution: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Encrpc 40mg Capsule contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

How Encrpc 40mg Capsule Works

Encrpc 40mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Encrpc 40mg Capsule

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Asthenia/fatigue/weakness
  • Back pain
  • Diarrhea
  • Cold like symptoms
  • Arthralgia (joint pain)
  • Hot flush
  • Peripheral edema
  • Musculoskeletal pain
  • Headache
  • Upper respiratory infection
  • Muscular weakness
  • Dizziness
  • Insomnia
  • Lower respiratory infection
  • Spinal cord compression
  • Cauda equina syndrome
  • Hematuria (blood in urine)
  • Paresthesia (tingling or prickling sensation)
  • Anxiety
  • Hypertension

What if I have taken an overdose of Encrpc 40mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Encrpc 40mg Capsule may include seizures. Seek immediate medical attention if you observe any symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Encrpc 40mg Capsule if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Encrpc 40mg Capsule or missing a dose. Talk to your doctor before taking Encrpc 40mg Capsule if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

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EnzalutamideLurasidone
Critical
EnzalutamideZiprasidone
Critical

Drug-Drug Interactions

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EnzalutamideLurasidone
Critical
How does the drug interact with Encrpc 40mg Capsule:
Co-administration of Lurasidone with Encrpc 40mg Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Encrpc 40mg Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideZiprasidone
Critical
How does the drug interact with Encrpc 40mg Capsule:
Taking Encrpc 40mg Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Encrpc 40mg Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Encrpc 40mg Capsule:
Co-administration of Encrpc 40mg Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Encrpc 40mg Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideRanolazine
Critical
How does the drug interact with Encrpc 40mg Capsule:
Taking Encrpc 40mg Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Encrpc 40mg Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideRegorafenib
Critical
How does the drug interact with Encrpc 40mg Capsule:
Taking Encrpc 40mg Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Encrpc 40mg Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideTicagrelor
Severe
How does the drug interact with Encrpc 40mg Capsule:
Co-administration of Encrpc 40mg Capsule with Ticagrelor may decrease the levels of Ticagrelor, which may make Ticagrelor less effective in treating your condition.

How to manage the interaction:
Taking Encrpc 40mg Capsule with Ticagrelor together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual symptoms, you should consult a doctor immediately. Do not stop using any medications without consulting a doctor.
EnzalutamideAmlodipine
Severe
How does the drug interact with Encrpc 40mg Capsule:
Using a combination of amlodipine and Encrpc 40mg Capsule may drastically lower amlodipine blood levels, making the medicine less effective.

How to manage the interaction:
Taking amlodipine with Encrpc 40mg Capsule can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
EnzalutamideMetrizamide
Severe
How does the drug interact with Encrpc 40mg Capsule:
Taking Encrpc 40mg Capsule with Metrizamide can increase the risk of seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Encrpc 40mg Capsule and Metrizamide, you can take these medicines together if prescribed by your doctor. If you experience any unusual symptoms, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideAripiprazole
Severe
How does the drug interact with Encrpc 40mg Capsule:
When Aripiprazole is taken with Encrpc 40mg Capsule, the amount of Aripiprazole in the blood may decrease. This might reduce aripiprazole's ability to effectively treat disease.

How to manage the interaction:
Although there is a possible interaction between Encrpc 40mg Capsule and Aripiprazole, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideNimodipine
Severe
How does the drug interact with Encrpc 40mg Capsule:
Co-administration of Nimodipine with Encrpc 40mg Capsule may make the medication less effective.

How to manage the interaction:
Although taking Nimodipine and Encrpc 40mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's Wort products during Encrpc 40mg Capsule treatment may lead to decrease in the effectiveness of Encrpc 40mg Capsule. Avoid St. John's Wort products during Encrpc 40mg Capsule treatment

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Encrpc 40mg Capsule Substitute

Substitutes safety advice
  • Enzamide 40mg Capsule 28's

    by AYUR

    336.79per tablet
  • Obnyx Capsule 4's

    by AYUR

    192.60per tablet
  • Azel 40 mg Capsule 28's

    by AYUR

    254.79per tablet
  • Xylutide 40 Softgel Cap 4'S

    250.43per tablet
  • Adleap 40 mg Capsule 28's

    140.29per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Encrpc 40mg Capsule.

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Pregnancy

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Caution

Encrpc 40mg Capsule may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Consult your doctor

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Encrpc 40mg Capsule in pediatric patients have not been established.

FAQs

Encrpc 40mg Capsule is used to treat prostate cancer in men.
Most prostate cancers require testosterone to grow. Encrpc 40mg Capsule contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Encrpc 40mg Capsule can slow the cancer's growth and cause it to shrink.
Encrpc 40mg Capsule is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.
In some cases, Encrpc 40mg Capsule may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.
Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.
Seizures may occur in patients receiving Encrpc 40mg Capsule. So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.
Yes, Enzalutamide was generally a well-tolerated medication. Take Encrpc 40mg Capsule pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Encrpc 40mg Capsule unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Encrpc 40mg Capsule therapy or adjust your Encrpc 40mg Capsule dose.

Manufacturer/Marketer address

H.O Kumud Apartment, 14A, Monohar Pukur Road, Kolkata : 700026
Other Info - EN25559

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