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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Encorate Chrono 200 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat mood disorders and migraine. It contains Sodium valproate and Valproic acid, which works by decreasing the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. It blocks the nerve transmission across the brain and provides a calming effect. In some cases, it may cause common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Encorate Chrono 200 Tablet

Encorate Chrono 200 Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Encorate Chrono 200 Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations.
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Encorate Chrono 200 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Encorate Chrono 200 Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Encorate Chrono 200 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Encorate Chrono 200 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side effects persistently.
 
Do not take Encorate Chrono 200 Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Encorate Chrono 200 Tablet . Consult your doctor before taking Encorate Chrono 200 Tablet if you are breastfeeding. Encorate Chrono 200 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Encorate Chrono 200 Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Encorate Chrono 200 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Encorate Chrono 200 Tablet

Treatment of Epilepsy, Mood disorder, Migraine.

Directions for Use

Take Encorate Chrono 200 Tablet with or 1 hour prior to food. Swallow Encorate Chrono 200 Tablet a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Encorate Chrono 200 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Encorate Chrono 200 Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Encorate Chrono 200 Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Encorate Chrono 200 Tablet is used to treat certain forms of epilepsy, such as petit mal epilepsy (short-term unconsciousness due to a disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Encorate Chrono 200 Tablet may also be used to treat epilepsy, which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy, which is not associated with movements and epilepsy, with symptoms affecting perception and deliberate movements. Encorate Chrono 200 Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

How Encorate Chrono 200 Tablet Works

Encorate Chrono 200 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Encorate Chrono 200 Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Encorate Chrono 200 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Encorate Chrono 200 Tablet

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

What if I have taken an overdose of Encorate Chrono 200 Tablet

Do not take more than the prescribed dose of Encorate Chrono 200 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Encorate Chrono 200 Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Encorate Chrono 200 Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Encorate Chrono 200 Tablet . Please do not stop taking Encorate Chrono 200 Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Encorate Chrono 200 Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Encorate Chrono 200 Tablet . Consult your doctor before taking Encorate Chrono 200 Tablet if you are breastfeeding. Encorate Chrono 200 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Encorate Chrono 200 Tablet as it could lead to increased risk of seizures. Care should be taken while giving Encorate Chrono 200 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Coadministration of Glycerol phenylbutyrate and Encorate Chrono 200 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Encorate Chrono 200 Tablet 10's together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Combining Sodium phenylbutyrate and Encorate Chrono 200 Tablet 10's can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Encorate Chrono 200 Tablet 10's is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DivalproexKetoconazole
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Coadministration of Ketoconazole and Encorate Chrono 200 Tablet 10's may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Encorate Chrono 200 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexErtapenem
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Coadministration of Ertapenem with Encorate Chrono 200 Tablet 10's may reduce the blood levels of Encorate Chrono 200 Tablet 10's and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Encorate Chrono 200 Tablet 10's if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexSodium oxybate
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Co-administration of Sodium oxybate and Encorate Chrono 200 Tablet 10's can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Encorate Chrono 200 Tablet 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexEsketamine
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Coadministration of Esketamine and Encorate Chrono 200 Tablet 10's can increase the side effects of esketamine.

How to manage the interaction:
Although taking Encorate Chrono 200 Tablet 10's and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexLeflunomide
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Co-administration of Encorate Chrono 200 Tablet 10's and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Encorate Chrono 200 Tablet 10's and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexLomitapide
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Co-administration of Encorate Chrono 200 Tablet 10's and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Encorate Chrono 200 Tablet 10's and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Co-administration of Encorate Chrono 200 Tablet 10's and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Encorate Chrono 200 Tablet 10's and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexKetamine
Severe
How does the drug interact with Encorate Chrono 200 Tablet 10's:
Co-administration of Encorate Chrono 200 Tablet 10's and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Encorate Chrono 200 Tablet 10's and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan; this helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Encorate Chrono 200 Tablet Substitute

Substitutes safety advice
  • Valprid-CR 200 Tablet 15's

    6.78per tablet
  • Valtec CR-200 Tablet 10's

    5.40per tablet
  • Torvate Chrono 200 Tablet 10's

    3.38per tablet
  • Soval Chrono 200 Tablet 10's

    3.38per tablet
  • Valpo CR-200 Tablet 10's

    4.91per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Encorate Chrono 200 Tablet as it may increase the risk of seizures.

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Pregnancy

Unsafe

Encorate Chrono 200 Tablet belongs to pregnancy category D. Avoid taking Encorate Chrono 200 Tablet if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects.

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Breast Feeding

Caution

Encorate Chrono 200 Tablet may pass into breastmilk. Consult your doctor before taking Encorate Chrono 200 Tablet if you are breastfeeding.

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Driving

Unsafe

Encorate Chrono 200 Tablet causes dizziness, sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Encorate Chrono 200 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Encorate Chrono 200 Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

FAQs

Encorate Chrono 200 Tablet is primarily used to treat epilepsy/seizures/fits. It is also used to treat mood disorders and migraine.
Encorate Chrono 200 Tablet decreases the excessive and abnormal nerve activity in the brain. Encorate Chrono 200 Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.
Do not discontinue Encorate Chrono 200 Tablet without consulting your doctor. To treat your condition effectually, continue taking Encorate Chrono 200 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Encorate Chrono 200 Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.
Encorate Chrono 200 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.
Encorate Chrono 200 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.
Encorate Chrono 200 Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Encorate Chrono 200 Tablet with aspirin to avoid unpleasant side-effects. Encorate Chrono 200 Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.
Encorate Chrono 200 Tablet contains sodium valproate and valproic acid as the active ingredients. It is used for the treatment of all types of epilepsy.
Take Encorate Chrono 200 Tablet with or after food as advised by your doctor.
You are recommended to avoid consumption of alcohol while taking Encorate Chrono 200 Tablet as it may increase the risk of seizures.
No, Encorate Chrono 200 Tablet does not cause addiction. However, it should be taken as per dose and duration prescribed by your doctor. Avoid self-medication as it may have severe unwanted effects.
Encorate Chrono 200 Tablet does not cure epilepsy, it only prevents the seizures from occurring. Therefore, you may need to continue taking it for years. If you experience any problems while taking Encorate Chrono 200 Tablet , please consult your doctor.
You are recommended not to stop taking Encorate Chrono 200 Tablet suddenly as it may increase the chances of recurrence of seizures. Therefore, it should be discontinued gradually. If you feel the need to stop taking Encorate Chrono 200 Tablet , always consult your doctor.
Yes, Encorate Chrono 200 Tablet may cause weight gain. To control your weight, you should eat a healthy balanced diet and exercise regularly. If you have any other concerns, consult your doctor.
Yes, Encorate Chrono 200 Tablet has no influence on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Encorate Chrono 200 Tablet and seizures may occur. Thus, it is essential to inform your doctor if you are using birth control pills. Your doctor will monitor your response to the treatment and Encorate Chrono 200 Tablet levels in your blood.
Long term use of Encorate Chrono 200 Tablet is safe for large number of patients. Rarely, using Encorate Chrono 200 Tablet for long term may weaken your bones, thereby increasing their chances of breaking easily (osteopenia and osteoporosis). Get regular check-ups done for bone health if you are taking Encorate Chrono 200 Tablet for a prolonged time.
Encorate Chrono 200 Tablet may cause change of hair colour, thinning of hair, and even hair loss. If you have any concerns, discuss with your doctor if it is possible to reduce the dose of Encorate Chrono 200 Tablet . Your hair may regrow after either switching to a different medicine or reducing your dose.
Encorate Chrono 200 Tablet may cause side effects such as nausea, diarrhoea, hair loss, weight gain, headache and irregular periods. If these side effects persist or worsen, please consult your doctor.
You are recommended to avoid taking Encorate Chrono 200 Tablet if you have known hypersensitivity to valproic acid, have liver disease, or are pregnant. It should be used with caution in kidney impairment patients.
Encorate Chrono 200 Tablet overdose can cause serious symptoms such as metabolic acidosis and deep coma. If you suspect you have taken overdose of Encorate Chrono 200 Tablet , seek medical help immediately.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ENC0010

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