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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ENBREL 25MG INJECTION is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, and Plaque psoriasis. It contains Etanercept, which works by blocking the effects of TNF-alpha, a pro-inflammatory cytokine that becomes elevated in psoriasis, rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis. Common side effects of this medication include tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problems, redness on the skin and arms, and injection site reactions.

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Composition :

ETANERCEPT-25MG

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About ENBREL 25MG INJECTION

ENBREL 25MG INJECTION is an immunosuppressant medicine that helps reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis. ENBREL 25MG INJECTION is generally used alone or in combination with methotrexate medicine.

ENBREL 25MG INJECTION consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

ENBREL 25MG INJECTION may cause certain side effects such as tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problem, redness on the skin and arms, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. ENBREL 25MG INJECTION is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. ENBREL 25MG INJECTION may cause dizziness, so drive only if you are alert and focused. ENBREL 25MG INJECTION should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of liver damage. ENBREL 25MG INJECTION is not recommended for use in pregnant and nursing mothers as it can cause serious adverse effects on the baby.

Uses of ENBREL 25MG INJECTION

Treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis and Plaque psoriasis

Directions for Use

ENBREL 25MG INJECTION will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

ENBREL 25MG INJECTION consists of Etanercept, which belongs to TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and other autoimmune disorders.

How ENBREL 25MG INJECTION Works

ENBREL 25MG INJECTION consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ENBREL 25MG INJECTION

  • Tingling or numbness
  • Dizziness
  • Shortness of breath
  • Bleeding
  • Bruising
  • Vision problem
  • Redness on the skin and arms
  • Injection site reactions

What if I have taken an overdose of ENBREL 25MG INJECTION

Since ENBREL 25MG INJECTION is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), and diabetes as it can worsen your health condition. Do not take live vaccines while being treated with ENBREL 25MG INJECTION to prevent any serious consequences. ENBREL 25MG INJECTION may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of stomach bleeding/ulcers. ENBREL 25MG INJECTION is not recommended for use in children below two years of age as safety and efficacy is not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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EtanerceptCapecitabine
Severe
EtanerceptVinblastine
Severe

Drug-Drug Interactions

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EtanerceptCapecitabine
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Co-administration of ENBREL 25MG INJECTION with Capecitabine may increase the risk or severity of infection may increase.

How to manage the interaction:
Co-administration of ENBREL 25MG INJECTION with Capecitabine can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptVinblastine
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Vinblastine, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of ENBREL 25MG INJECTION with Vinblastine can result in an interaction, but it can be taken if your doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptPomalidomide
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Pomalidomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Pomalidomide and ENBREL 25MG INJECTION, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptMethylprednisolone
Severe
How does the drug interact with ENBREL 25MG INJECTION:
The use of ENBREL 25MG INJECTION with Methylprednisolone can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between ENBREL 25MG INJECTION and Methylprednisolone, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
EtanerceptThalidomide
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Taking Thalidomide with ENBREL 25MG INJECTION may increase the risk of serious infection.

How to manage the interaction:
Although taking thalidomide and ENBREL 25MG INJECTION together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
EtanerceptValganciclovir
Severe
How does the drug interact with ENBREL 25MG INJECTION:
The combined use of ENBREL 25MG INJECTION and valganciclovir can increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Valganciclovir and ENBREL 25MG INJECTION, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
EtanerceptAntithymocyte Globulin
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Antithymocyte Globulin, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Antithymocyte Globulin and ENBREL 25MG INJECTION, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptZidovudine
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with zidovudine, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking ENBREL 25MG INJECTION with Zidovudine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptLevamisole
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Taking ENBREL 25MG INJECTION together with levamisole may increase the risk of serious infections.

How to manage the interaction:
Although using ENBREL 25MG INJECTION together with levamisole can result in an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort or burning during urination. Do not stop taking any medications without consulting a doctor.
EtanerceptCisplatin
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Cisplatin, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between ENBREL 25MG INJECTION and Cisplatin, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

ENBREL 25MG INJECTION Substitute

Substitutes safety advice
  • Intacept 25 Inj

    by AYUR

    4685.50per tablet
  • Etacept 25mg Injection 3ml

    by AYUR

    819.73per tablet
  • Rymti 25Mg/0.5Ml Inj

    4674.00per tablet
  • Etanerrel 25mg Injection

    4879.00per tablet
  • Etacept PFS 25 mg Injection 0.5 ml

    2870.00per tablet
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Alcohol

Unsafe

Avoid alcohol consumption as alcohol intake, along with ENBREL 25MG INJECTION, may cause increased dizziness and risk of stomach bleeding/ulcers.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant, or planning pregnancy inform your doctor before receiving ENBREL 25MG INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass in to breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving ENBREL 25MG INJECTION. Your doctor may suggest you to stop feeding while on treatment with this medicine

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Driving

Unsafe

ENBREL 25MG INJECTION may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness.

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Liver

Caution

ENBREL 25MG INJECTION should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment. However, ENBREL 25MG INJECTION is not recommended in patients with active liver diseases.

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Kidney

Caution

ENBREL 25MG INJECTION should be used with caution if you have kidney impairment. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

ENBREL 25MG INJECTION is not recommended in children below two years of age as the safety and efficacy is not established. In children above two years of age, it will be administered by the paediatrician.

FAQs

ENBREL 25MG INJECTION is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis and Plaque psoriasis.
ENBREL 25MG INJECTION consists of Etanercept, which belong to TNF (Tumor necrosis factor) inhibitor class of drug. It works by inhibiting the TNF-α and TNF-β binding to the cell surface and therby makes the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.
ENBREL 25MG INJECTION affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis, hepatitis B, or abnormal liver enzymes. ENBREL 25MG INJECTION can also increase the risk of developing cancers; hence, mentioning your doctor if you have a history of any cancer is essential.
Yes, ENBREL 25MG INJECTION is a disease-modifying anti-rheumatic drug (DMARD) that works by inhibiting tumour necrosis factor (TNF), a key protein involved in the inflammatory response. By blocking TNF, it helps reduce inflammation, manage symptoms of autoimmune diseases like rheumatoid arthritis, and slow disease progression.
ENBREL 25MG INJECTION is neither a steroid nor a monoclonal antibody. It is a biological medicine classified as a TNF inhibitor. It is a fusion protein that binds to tumour necrosis factor (TNF) and prevents it from causing inflammation in autoimmune conditions like rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis.
Yes, ENBREL 25MG INJECTION is safe as it is administered by the doctor or nurse in prescribed dose and duration. Ensure you do not skip scheduled appointments to maintain safety and monitor your progress effectively.
ENBREL 25MG INJECTION may cause weight gain if you use it for a longer duration. If you notice any weight changes, manage stress, exercise regularly, eat a nutritious-rich diet, take a fibre-rich diet, stay hydrated, and cut down on sugary foods and drinks.
ENBREL 25MG INJECTION may cause hair loss in some individuals. If you experience this symptom, manage stress, use gentle hair care practices, and eat nutritious rich food. However, if hair loss persists consult the doctor for further guidance.
ENBREL 25MG INJECTION typically starts to show some effects within one to two weeks. However, it may take 3 to 6 months for noticeable improvement.
The side effects of ENBREL 25MG INJECTION include tingling or numbness, shortness of breath, bleeding, dizziness, pale skin, bruising, vision problems, redness on the skin and arms, and injection site reactions. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802 / 1901, Plot No. C-70, G-Block,Bandra Kurla Complex, Bandra (East),Mumbai,Maharashtra,INDIA,400051.
Other Info - ENB0001

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