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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Enapril-HT Tablet is used to treat hypertension (high blood pressure). It contains Enalapril and Hydrochlorothiazide, which decreases the constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Also, it removes excess water and certain salts such as sodium and potassium from the blood. This reduces the fluid volume circulating through blood vessels and lower high blood pressure. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Enapril-HT Tablet

Enapril-HT Tablet belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Enapril-HT Tablet is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take Enapril-HT Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of Enapril-HT Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Enapril-HT Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enapril-HT Tablet . Avoid potassium supplements with Enapril-HT Tablet as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enapril-HT Tablet .

Uses of Enapril-HT Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take Enapril-HT Tablet with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Enapril-HT Tablet is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

How Enapril-HT Tablet Works

Enapril-HT Tablet is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enapril-HT Tablet

  • Dizziness
  • Weakness
  • Blurred vision
  • Nausea
  • Headache
  • Orthostatic hypotension (low blood pressure when standing up from lying or sitting position)
  • High cholesterol or uric acid levels
  • Electrolyte imbalance
  • Diarrhoea
  • Chest pain
  • Fast heartbeat
  • Changes in taste
  • Stomach pain

What if I have taken an overdose of Enapril-HT Tablet

Do not take more than the prescribed dose of Enapril-HT Tablet as it may cause overdose. The symptoms of overdose include light-headedness, dizziness or fainting. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Enapril-HT Tablet or any other medicines, please tell your doctor. Enapril-HT Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enapril-HT Tablet . It is advised to complete the full course of medication and do not suddenly stop taking Enapril-HT Tablet as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with Enapril-HT Tablet as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking Enapril-HT Tablet . If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enapril-HT Tablet . 

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Enapril-HT Tablet:
Using aliskiren together with Enapril-HT Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enapril-HT Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Enapril-HT Tablet:
Taking Cisapride and Enapril-HT Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Enapril-HT Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Enapril-HT Tablet:
Taking Dofetilide and Enapril-HT Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Enapril-HT Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EnalaprilAmiloride
Severe
How does the drug interact with Enapril-HT Tablet:
Due to the additive effect, the coadministration of Enapril-HT Tablet and Amiloride (potassium-sparing diuretic) may increase blood potassium levels. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Allopurinol may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any signs and symptoms of hyperkalemia like, weakness, confusion, numbness or tingling, and uneven heartbeats, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
EnalaprilAmiloride
Severe
How does the drug interact with Enapril-HT Tablet:
Using Enapril-HT Tablet together with amiloride may increase the levels of potassium in your blood, especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking amiloride and Enapril-HT Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not discontinue any medications without a doctor's advice.
EnalaprilLeflunomide
Severe
How does the drug interact with Enapril-HT Tablet:
Combining Enapril-HT Tablet with Leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Enapril-HT Tablet and leflunomide, it can be taken if prescribed by a doctor. However, contact your doctor immediately if you experience joint pain or swelling, itching, fatigue, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to your doctor.
EnalaprilOlmesartan medoxomil
Severe
How does the drug interact with Enapril-HT Tablet:
Using Enapril-HT Tablet together with olmesartan medoxomil may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Co-administration of Enapril-HT Tablet with Olmesartan medoxomil may lead to interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
EnalaprilTelmisartan
Severe
How does the drug interact with Enapril-HT Tablet:
Coadministration of Enapril-HT Tablet with Telmisartan may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Enapril-HT Tablet together with Telmisartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, papayas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilFERRIC CARBOXYMALTOSE
Severe
How does the drug interact with Enapril-HT Tablet:
Taking Enapril-HT Tablet and Ferric Carboxymaltoside increases the side effects of Enapril-HT Tablet.

How to manage the interaction:
Although taking Enapril-HT Tablet with Ferric Carboxymaltose may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, headache, blurred vision, or chest pain, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
EnalaprilPotassium iodide
Severe
How does the drug interact with Enapril-HT Tablet:
Combining Potassium Iodide with Enapril-HT Tablet can increase the risk of hyperkalemia.

How to manage the interaction:
Co-administration of Enapril-HT Tablet with Potassium iodide can possibly result in an interaction, but it can be taken if your doctor has advised it. however contact a doctor if you experience nausea, vomiting, tingling in hands and feet, confusion, and irregular heart beat. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of potassium rich food while on the treatment with Enapril-HT Tablet can lead to weakness, confusion, numbness of tingling sensation in hands or legs, or slow or rapid heartbeat. Avoid or limit consumption of potassium rich food while on the treatment with Enapril-HT Tablet.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Enapril-HT Tablet Substitute

Substitutes safety advice
  • El-Ht Tablet 10's

    by Others

    5.36per tablet
  • Vasonorm H 10 mg/25 mg Tablet

    by Others

    2.68per tablet
  • Enzide 10 mg/25 mg Tablet

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    2.88per tablet
  • Enatol HT Tablet 10's

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    5.99per tablet
  • ENACE D 10MG TABLET 30S

    by Others

    12.03per tablet
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Alcohol

Unsafe

Avoid alcohol consumption with Enapril-HT Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

Please consult a doctor if you are pregnant. Enapril-HT Tablet is not recommended for pregnant women, especially in the second and third trimesters as it may cause birth defects or serious harm to the baby.

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Breast Feeding

Unsafe

Enapril-HT Tablet may be excreted in human milk. Therefore, Enapril-HT Tablet is not recommended for breastfeeding mothers as it may be unsafe for the baby. However, please consult a doctor.

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Driving

Caution

Enapril-HT Tablet may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Enapril-HT Tablet .

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Liver

Caution

Enapril-HT Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Enapril-HT Tablet if you have severe liver problems.

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Kidney

Caution

Enapril-HT Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Enapril-HT Tablet if you have severe kidney problems.

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Children

Unsafe

It is not recommended for children as the safety and effectiveness were not established.

FAQs

Enapril-HT Tablet is used to treat hypertension (high blood pressure).

Enapril-HT Tablet contains Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

You are not recommended to take furosemide with Enapril-HT Tablet as co-administration of these two medicines may increase the risk of low blood pressure. However, if you experience dizziness, reduced heart rate, headache or fainting, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

It is advised to inform your doctor if you have had skin cancer or develop an unexpected skin lesion as hydrochlorothiazide in Enapril-HT Tablet may increase the risk of certain types of skin and lip cancer especially when taken in high doses for a long period. Therefore, it is recommended to protect the skin from UV rays and sun exposure while taking Enapril-HT Tablet .

No, you are not recommended to take potassium supplements with Enapril-HT Tablet as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines with Enapril-HT Tablet .

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ENA0009

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