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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Enam 5 Tablet is used to treat high blood pressure and heart failure. It contains Enalapril, which widens and relaxes the blood vessels and, therefore, help lower high blood pressure. In some cases, you may experience side effects such as headaches, ankle swelling, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ENALAPRIL-5MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Enam 5 Tablet

Enam 5 Tablet is used to treat high blood pressure and heart failure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Enam 5 Tablet lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Enam 5 Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure. 

In some cases, you may experience headaches, ankle swelling, slow heart rate, and nausea. Enam 5 Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery. Most of these side effects of Enam 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Even if your blood pressure becomes normal, you should not stop using Enam 5 Tablet ; doing so may worsen your condition. Let your doctor know if you have had or currently have any liver, kidney, or heart problems. During pregnancy and lactation, Enam 5 Tablet should be only taken after consulting your doctor. You should regularly monitor your blood pressure and heart rate.

Uses of Enam 5 Tablet

Treatment of High blood pressure, Prevention of Congestive heart failure.

Directions for Use

Swallow Enam 5 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Enam 5 Tablet is primarily used to treat hypertension or high blood pressure. In combination therapy, it is also prescribed with other drugs, like thiazide diuretics (water pills). Besides, Enam 5 Tablet prevents congestive heart failure in combination with diuretics (water pills) and cardiac glycosides like digitalis. In these patients, Enam 5 Tablet improves heart complications, increases survival, and reduces hospitalization frequency.

How Enam 5 Tablet Works

Enam 5 Tablet lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Enam 5 Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enam 5 Tablet

  • Cough
  • Dizziness
  • Vision blurred
  • Weakness
  • Nausea (feeling sick)

What if I have taken an overdose of Enam 5 Tablet

Do not take more than the prescribed dose of Enam 5 Tablet as it may cause overdose. The symptoms of overdose include sleepiness, dizziness and pounding heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Enam 5 Tablet should not be given to the people allergic to Enam 5 Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, tell your doctor if you have low blood pressure (hypotension),  heart disease, liver disease, kidney disease, or are currently on dialysis. Enam 5 Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The level of raised bilirubin has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye etc.) should take the Enam 5 Tablet with caution. Do not take Enam 5 Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor that, you are using Enam 5 Tablet before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery.

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
EnalaprilOlmesartan medoxomil
Severe

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Enam 5 Tablet 15's:
Using aliskiren together with Enam 5 Tablet 15's may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enam 5 Tablet 15's with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
EnalaprilOlmesartan medoxomil
Severe
How does the drug interact with Enam 5 Tablet 15's:
Coadministration of Olmesartan medoxomil with Enam 5 Tablet 15's can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking olmesartan medoxomil together with Enam 5 Tablet 15's may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilLomitapide
Severe
How does the drug interact with Enam 5 Tablet 15's:
Combining lipitapide with other drugs that can damage the liver, including Enam 5 Tablet 15's, increases the risk of liver issues.

How to manage the interaction:
Although taking Enam 5 Tablet 15's and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - joint pain, swelling, skin rash, itching, abdominal pain, or dark urine - immediately contact your doctor. Do not stop using any medications without a doctor's advice.
EnalaprilPotassium chloride
Severe
How does the drug interact with Enam 5 Tablet 15's:
Taking Enam 5 Tablet 15's with potassium chloride increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 5 Tablet 15's together with Potassium chloride may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilAllopurinol
Severe
How does the drug interact with Enam 5 Tablet 15's:
Co-administration of Allopurinol with Enam 5 Tablet 15's increase the risk of severe allergic reactions and infections.

How to manage the interaction:
There may be a possibility of interaction between Allopurinol and Enam 5 Tablet 15's, but it can be taken if prescribed by a doctor. If you experience swelling, itching, rashes, fever, muscle pain, weakness, chills, sore throat, or fatigue, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Enam 5 Tablet 15's:
Taking potassium citrate with Enam 5 Tablet 15's may increase potassium levels in the blood, leading to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Enam 5 Tablet 15's with Potassium citrate can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without a doctor's advice.
EnalaprilTrimethoprim
Severe
How does the drug interact with Enam 5 Tablet 15's:
Enam 5 Tablet 15's combined with Trimethoprim can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enam 5 Tablet 15's together with Trimethoprim may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium chloride
Severe
How does the drug interact with Enam 5 Tablet 15's:
Co-administration of Potassium chloride with Enam 5 Tablet 15's may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Enam 5 Tablet 15's with Potassium chloride can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
EnalaprilValsartan
Severe
How does the drug interact with Enam 5 Tablet 15's:
Combine use of Enam 5 Tablet 15's and Valsartan can increase the effect of Valsartan.

How to manage the interaction:
Although taking Enam 5 Tablet 15's together with Valsartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
EnalaprilTelmisartan
Severe
How does the drug interact with Enam 5 Tablet 15's:
Co-administration of Enam 5 Tablet 15's with Telmisartan can increase the risk of kidney failure, low blood pressure, and high potassium levels.

How to manage the interaction:
Although there is a possible interaction between Enam 5 Tablet 15's and Telmisartan, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience nausea, vomiting, weakness, tingling of the hands and feet, or feelings of heaviness in the legs, so it's important to seek medical help. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming a high-potassium diet while taking Enam 5 Tablet 15's can cause hyperkalemia (elevated blood potassium levels). Hyperkalemia may lead to dizziness, lightheadedness, fainting, or a rapid heartbeat. Avoid the consumption of potassium-rich foods.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two serving for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Enam 5 Tablet Substitute

Substitutes safety advice
  • Envas Tablet 15's

    3.72per tablet
  • Enapril 5 Tablet 15's

    3.72per tablet
  • Nuril-5 Tablet 10's

    3.69per tablet
  • Enace 5 Tablet 15's

    3.72per tablet
  • Dilvas 5 Tablet 10's

    3.69per tablet
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Alcohol

Unsafe

Enam 5 Tablet may enhance the hypotensive (low blood pressure) effect of this drug. For better advise, you should consult your doctor whether you can take Enam 5 Tablet with alcohol.

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Pregnancy

Unsafe

The use of Enam 5 Tablet or any ACE inhibitors is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Enam 5 Tablet .

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Breast Feeding

Caution

Use of Enam 5 Tablet is not recommended during breastfeeding stage.

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Driving

Unsafe

Drive with caution, Enam 5 Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) have been observed while taking Enam 5 Tablet , so it has to be taken with caution. Especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Enam 5 Tablet to be taken with caution, especially in case of severe kidney disease. Dose may have to be adjusted by your doctor. Enam 5 Tablet should be given with precaution in hemodialysis condtion.

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Children

Caution

Enam 5 Tablet is not recommended for children. The safety and effectivenss of Enam 5 Tablet has not been established in children due to limited testing of this drug on children by competent authorities across the world. If necessary, your doctor will decide whether to give Enam 5 Tablet or not.

FAQs

Enam 5 Tablet is used to treat high blood pressure and heart failure.
Enam 5 Tablet is an angiotensin-converting enzyme (ACE) inhibitor. It works by inhibiting a chemical in the body that causes blood vessels to constrict. As a result, enalapril relaxes the blood vessels. This decreases blood pressure while increasing the delivery of blood and oxygen to the heart.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up any time. If you have any discomfort, please consult your doctor immediately.
Before surgery, you should inform your doctor that you are taking Enam 5 Tablet as it can reduce your blood pressure when used along with anaesthesia which is given before a major operation.
If you forget to take Enam 5 Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
Enam 5 Tablet may cause side effects such as nausea, weakness, cough, dizziness and blurred vision. If these side effects persist or worsen, please consult your doctor.
No, Enam 5 Tablet does not cause excessive urination. Normal kidney function may not be affected by Enam 5 Tablet . However, when Enam 5 Tablet is given with a diuretic (water pill, a medicine that increases the urine output), kidney damage may occur. In this case, either the diuretic should be stopped or its dose should be lowered. If you have severe heart failure or your kidneys are already affected then there is a risk of kidney failure. However, kidney damage can be reversed by timely and appropriate treatment.
Rarely, Enam 5 Tablet may cause yellowing of skin and eyes, an increase in liver enzymes and loss of appetite. Additionally, it might cause significant liver damage and even death. Therefore, if you experience any such symptoms, contact your doctor immediately.
You should be cautious when taking Enam 5 Tablet with hydrochlorothiazide, as it can further lower your blood pressure. You may also develop kidney failure symptoms, such as a reduced amount of urine, swelling of your legs, ankles, and feet from water retention. While others may experience unexplained shortness of breath, persistent nausea, excessive drowsiness or fatigue, pain, confusion, or pressure in your chest and seizures (fits). These symptoms typically occur if there is considerable water or salt loss prior to starting Enam 5 Tablet . Therefore, if you experience any of these symptoms, contact your doctor who will either advise you to stop taking hydrochlorothiazide or lower the dose. The doctor may also recommend you Enam 5 Tablet in very low doses when used in combination with hydrochlorothiazide.
You are recommended to avoid taking ibuprofen with Enam 5 Tablet as there is a risk of kidney damage and may reduce the effectiveness of Enam 5 Tablet . However, please consult your doctor before taking Enam 5 Tablet with other medicines.
Enam 5 Tablet starts working within few hours. However, it may take few weeks to see its full effects. After taking Enam 5 Tablet for high blood pressure, you may not notice any difference until you get your blood pressure checked. It may take few weeks to months before you start feeling better, if you are taking Enam 5 Tablet for heart failure.
You should take Enam 5 Tablet for as long as it is advised by your doctor. You might need to take it lifelong, until and unless any serious side effect starts bothering and stops you from taking it. However, do not stop taking it without first consulting your doctor.
Yes, Enam 5 Tablet can be taken for long term as it is generally well tolerated by most people. However, long-term usage of it can sometimes impair your kidneys functioning. Your doctor will recommend regular blood tests to check whether your kidneys are functioning properly or not.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - ENA0007

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