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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Eligard 45 mg Injection is used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. It contains Leuprolide which works by inhibiting the synthesis of testosterone in men and oestrogen in women. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LEUPROLIDE-45MG

Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Eligard 45 mg Injection

Eligard 45 mg Injection belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Eligard 45 mg Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Take Eligard 45 mg Injection as prescribed by your doctor. Your doctor will decide the dosage depending on your medical condition. The common side effects of Eligard 45 mg Injection include hot flashes, decreased sexual interest, shrinking of the testicles, breast tenderness or swelling, dizziness, headache, nausea, vomiting, diarrhoea, upset stomach and injection site pain reaction. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

To treat your condition effectually continue taking Eligard 45 mg Injection for as long as your doctor has prescribed. Do not stop Eligard 45 mg Injection midway.  Avoid taking Eligard 45 mg Injection if you are pregnant or breastfeeding because this Eligard 45 mg Injection can cause harmful effects on the unborn baby. Both women and men using this Eligard 45 mg Injection should use birth control to avoid pregnancy. Eligard 45 mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Eligard 45 mg Injection is not recommended for children below two years of age. Eligard 45 mg Injection may make you feel dizzy, hence drive when you are alert only.

Uses of Eligard 45 mg Injection

Treatment of Prostate cancer, Breast cancer, Endometriosis, Precocious puberty.

Directions for Use

Eligard 45 mg Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Eligard 45 mg Injection contains Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. Eligard 45 mg Injection is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, Eligard 45 mg Injection works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. Eligard 45 mg Injection reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis and breast cancer.

How Eligard 45 mg Injection Works

Eligard 45 mg Injection contains Leuprolide that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. It works by inhibiting the synthesis of the natural male hormone, testosterone in men and oestrogen in women. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis and breast cancer in women.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eligard 45 mg Injection

  • Weight changes
  • Hot flushes
  • Muscle weakness
  • Bone Pain
  • Loss of interest in sexual intercourse
  • Inability to have an erection
  • Tiredness
  • Difficulty sleeping
  • Headaches
  • Breast tenderness
  • Changes in breast size
  • Mood swings
  • Abdominal pain
  • Vomiting (feeling sick)
  • Acne
  • Vaginal Bleeding 
  • Spotting
  • Injection site reactions (skin hardening, redness, pain, abscesses, swelling, nodules, ulcers and skin damage)

What if I have taken an overdose of Eligard 45 mg Injection

Since this medication is given by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Eligard 45 mg Injection or any other medicines, please tell your doctor. Eligard 45 mg Injection can affect the unborn baby when used in pregnancy. Hence, Eligard 45 mg Injection is not indicated for use in pregnancy and breastfeeding women. If you are using Eligard 45 mg Injection, make sure to use reliable forms of contraception to prevent pregnancy during the course. Eligard 45 mg Injection may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Use the Eligard 45 mg Injection with caution in elderly patients and children. Eligard 45 mg Injection is not recommended for children younger than two years of age. Your symptoms may become temporarily worse when you first start taking Eligard 45 mg Injection. Inform your doctor if this continues for longer than 2 months. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting Eligard 45 mg Injection, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. Eligard 45 mg Injection may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking Eligard 45 mg Injection. Eligard 45 mg Injection can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
LeuprorelinVandetanib
Critical

Drug-Drug Interactions

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LeuprorelinCisapride
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking leuprolide with cisapride can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Eligard 45 mg Injection 1's with Cisapride is not recommended, it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinVandetanib
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking Eligard 45 mg Injection 1's with Vandetanib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Vandetanib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinCitalopram
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Coadministration of Eligard 45 mg Injection 1's and citalopram can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's and citalopram together can possibly result in an interaction; they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinIbutilide
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Using ibutilide together with leuprolide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Ibutilide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinDofetilide
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking leuprolide with dofetilide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Dofetilide together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LeuprorelinPimozide
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking Eligard 45 mg Injection 1's with Pimozide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinNilotinib
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Using nilotinib together with leuprolide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Nilotinib is not recommended, as it can result in an interaction. It can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LeuprorelinEliglustat
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking Leuprolide and Eliglustat together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Eliglustat together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LeuprorelinSaquinavir
Critical
How does the drug interact with Eligard 45 mg Injection 1's:
Taking leuprolide with Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Eligard 45 mg Injection 1's with Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LeuprorelinOsimertinib
Severe
How does the drug interact with Eligard 45 mg Injection 1's:
Taking Eligard 45 mg Injection 1's and osimertinib together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Eligard 45 mg Injection 1's and osimertinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. 
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Eligard 45 mg Injection to avoid unpleasant side-effects. Alcohol intake, along with Eligard 45 mg Injection, may cause increased drowsiness.

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Pregnancy

Unsafe

Eligard 45 mg Injection is a pregnancy category X drug. Eligard 45 mg Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective method of contraception while taking fluorouracil and for at least 6 months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Eligard 45 mg Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Eligard 45 mg Injection causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Eligard 45 mg Injection.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Eligard 45 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Eligard 45 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Caution

Eligard 45 mg Injection is not recommended in children younger than two years of age.

FAQs

Eligard 45 mg Injection is used to treat prostate cancer in men, breast cancer & endometriosis in women and precocious puberty (early puberty) in children.
Eligard 45 mg Injection contains Leuprolide, a synthetic hormone that helps reduce the testosterone and oestrogen hormones in men and women, respectively. This process of lowering hormone levels can decrease cancer cell's growth in prostate cancer in men and shrinks endometriosis in women.
Yes, Eligard 45 mg Injection commonly affects the hair by making them thin which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen lowering effect of Eligard 45 mg Injection. These effects are not long-lasting and may return after some time. If it matters to you then inform your doctor for further advice.
Eligard 45 mg Injection may cause impotence and affect fertility in men. It is advised to speak to your doctor if you plan to have a family in the future before starting Eligard 45 mg Injection.
Eligard 45 mg Injection should be used with caution in diabetic patients as it may increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Eligard 45 mg Injection and inform your doctor if you have diabetes before taking Eligard 45 mg Injection.
Eligard 45 mg Injection may worsen your mood disorders like depression. Hence it is advised to use Eligard 45 mg Injection only when you are free from any kind of mental problems. Please consult your doctor for more information.
Eligard 45 mg Injection is not recommended for patients suffering from heart rhythm problems such as arrhythmia (irregular heartbeat) as it may increase the risk of heart rhythm problems. Therefore, inform your doctor if you have any heart problems before taking Eligard 45 mg Injection.
Eligard 45 mg Injection may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Eligard 45 mg Injection.
Before starting treatment with Eligard 45 mg Injection, you should inform your doctor if you are allergic to any of its ingredients. Let your doctor know if you are pregnant or breastfeeding, as Eligard 45 mg Injection could harm the unborn baby. Eligard 45 mg Injection may also affect fertility in men, so discuss with your doctor if you plan to start a family in the future. Also, make sure to inform your doctor if you have a history of liver or kidney disease, heart disease, recent heart attack, depression, brain tumours, electrolyte imbalances, diabetes, seizures, weak bones, or high cholesterol levels.
No, Eligard 45 mg Injection does not need to be refrigerated. It should be stored at room temperature, away from direct sunlight.
Eligard 45 mg Injection is typically administered by a healthcare provider either under the skin (subcutaneously) or into a muscle (intramuscularly). Please do not self-administer Eligard 45 mg Injection.
No, Eligard 45 mg Injection is not a chemotherapy medicine. Eligard 45 mg Injection is a hormonal medicine that belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It is a synthetic hormone that acts similarly to the GnRH hormone produced by the hypothalamus in the brain.
Yes, Eligard 45 mg Injection can stop periods. It is used to treat endometriosis, a condition where tissue similar to the lining of the uterus (womb) grows outside the uterus and causes painful or irregular periods. Eligard 45 mg Injection works by suppressing the production of hormones that regulate the menstrual cycle, which can create a temporary menopause-like state, stopping periods for a while.
Yes, Eligard 45 mg Injection is a hormonal medicine that works by suppressing the production of reproductive hormones in females. Using Eligard 45 mg Injection during pregnancy is not recommended, as it may harm the developing foetus (newborn baby). Its use should be avoided during pregnancy unless prescribed by your doctor.
Taking Eligard 45 mg Injection may affect your bone health by lowering certain hormone levels (such as oestrogen or testosterone), which can lead to decreased bone mineral density over time. Please consult your doctor about the potential risks of using Eligard 45 mg Injection and ask about steps you can take to help protect your bones.
Eligard 45 mg Injection may increase blood sugar levels (hyperglycaemia) or make existing diabetes worse. It is important to monitor your blood sugar levels while using Eligard 45 mg Injection and consult your doctor if you have any concerns before or during treatment.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ELI0013

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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